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Creator | Title | Description | Subject | Date |
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Couldwell, William T. | Intraoperative aneurysmal subarachnoid hemorrhage after rupture of a previously undiagnosed intracranial aneurysm during Chiari decompression: case report and literature review | Type 1 Chiari malformation occurs when caudal displacement of cerebellar tonsils below the level of foramen magnum obstructs the normal flow of cerebrospinal fluid (CSF) between the cranial and spinal spaces, a condition that often needs surgical decompression to restore normal CSF circulation. Abru... | | 2014-01-01 |
| 2 |
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Kestle, John R. W. | High incidence of tumor dissemination in myxopapillary ependymoma in pediatric patients | P Myxopapillary ependymomas (MPEs) have historically been thought to be benign tumors occurring most frequently in adults. Only 8 to 20% of these tumors occur in the first two decades of life, making this tumor a rarity in pediatric neurosurgery. Five patients with intraspinal MPEs were treated by t... | | 2005-01 |
| 3 |
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Kestle, John R. W. | High incidence of tumor dissemination in myxopapillary ependymoma in pediatric patients | P Myxopapillary ependymomas (MPEs) have historically been thought to be benign tumors occurring most frequently in adults. Only 8 to 20% of these tumors occur in the first two decades of life, making this tumor a rarity in pediatric neurosurgery. Five patients with intraspinal MPEs were treated by t... | Myxopapillary ependymoma; Tumor dissemination | 2005 |
| 4 |
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Swallow, Charles E.; Tsuruda, Jay S.; Digre, Kathleen B.; Glaser, Matthew J.; Davidson, H. Christian; Harnsberger, H. Ric | Terson syndrome: CT evaluation in 12 patients. | PURPOSE: Terson syndrome may be overlooked in the acute setting and often requires ophthalmologic intervention to prevent long-term visual loss. In this syndrome, vitreous or retinal hemorrhage results from an abrupt rise in intracranial pressure, leading to retinal venous hypertension and intraocul... | Retinal Hemorrhage; Visual Acuity; Vitreous Hemorrhage | 1998-04 |
| 5 |
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Schmidt, Meic H. | Castleman disease of the spine mimicking a nerve sheath tumor | Castleman disease is a rare lymphoproliferative disease of unknown cause. In most cases, afflicted patients present with a mediastinal mass although the disease may manifest in numerous other sites, including intracranially and rarely intraspinally. The authors report on the case of a 19-year-old wo... | Castleman disease; Nerve sheath tumor | 2007 |
| 6 |
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Kestle, John R. W. | Predicting slitlike ventricles in children on the basis of baseline characteristics at the time of shunt insertion | Object. Slit ventricle syndrome (SVS) is a delayed complication of shunt insertion and occurs only in children with slitlike ventricles after shunt placement. Although SVS appears to be related to early shunt placement, its predisposing factors are largely unknown. Methods. Baseline data in 737 chi... | Slitlike ventricles; Slit ventricle syndrome; Shunt insertion; Predictive factor; Ventriculoperitoneal shunt; Pediatric neurosurgery | 2007 |
| 7 |
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Kestle, John R. W. | Late rapid deterioration after endoscopic third ventriculostomy: additional cases and review of the literature | Object. Late rapid deterioration after endoscopic third ventriculostomy (ETV) is a rare complication. The authors previously reported three deaths from three centers. Three other deaths and a patient who experienced rapid deterioration have also been reported. Following the death at the University ... | Endoscopic third ventriculostomy; ETV; Pediatric neurosurgery; Adverse outcome | 2006 |
| 8 |
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Garber, Sarah | Spinal arteriovenous fistulas in children with hereditary hemorrhagic telangiectasia: report of 2 cases | Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant angiodysplasia with high penetrance and variable expression. The manifestations of HHT are often age related, and spinal arteriovenous fistula (AVF) may be the initial presentation of HHT in young children. Because spinal AVFs are... | | 2012-01-01 |
| 9 |
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Kestle, John R. W. | Change in ventricular size and effect of ventricular catheter placement in pediatric patients with shunted hydrocephalus | OBJECTIVE: The multicenter, randomized pediatric cerebrospinal fluid shunt valve design trial found no difference in the rate of shunt failure between a standard valve, a siphon-reducing valve (Delta; Medtronic PS Medical, Goleta, CA), and a flow-limiting valve (Orbis Sigma; Cordis, Miami, FL); ho... | Shunt failure; Valve design; Ventricular size; Ventricular catheter placement | 1999 |
| 10 |
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Couldwell, William T. | Inflammatory pseudotumor of the cavernous sinus and skull base | Inflammatory pseudotumor is a non-neoplastic process of unknown etiology characterized by a proliferation of connective tissue with an inflammatory infiltrate. Intracranial inflammatory pseudotumors classically involve the cavernous sinus but can also occur in the supratentorial or infratentorial c... | Intracranial neoplasm; Pseudotumor; Skull base | 2006 |
| 11 |
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Couldwell, William T.; Chin, Steven S. | Extranodal NK/T-cell lymphoma presenting as a pituitary mass | Extranodal NK/T-cell lymphomas are uncommon neoplasms that are highly aggressive and show a strong association with Epstein-Barr virus. They most commonly affect the nasal cavity and paranasal sinuses; manifestation as a primary pituitary tumor has never been described. The authors report a case of ... | | 2007-09 |
| 12 |
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Couldwell, William T. | Vagus nerve stimulation activates central nervous system structures in epileptic patients during PET H2(15)O blood flow imaging | OBJECTIVE: To determine the central areas of activation by vagal nerve stimulation (VNS) in epilepsy. VNS is a promising neurosurgical method for treating patients with partial and secondary generalized epilepsy. The anti-epileptic mechanism of action from VNS is not well understood. METHODS: We p... | Epilepsy; Positron emission tomography; Thalamus; Vagus nerve stimulation | 1996 |
| 13 |
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Couldwell, William T. | Assessment of long-term remission of acromegaly following surgery | Object. The criteria for remission of acromegaly following transsphenoidal adenoma resection are in evolution. In the present study the authors evaluate the utility of predicting long-term remission by reference to a single fasting growth hormone (GH) level on the 1st postoperative day. Methods. A ... | Acromegaly; Pituitary adenoma; Transsphenoidal surgery; Growth hormone; Insulin-like growth factor I | 2003-01-01 |
| 14 |
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Schmidt, Meic H. | Pigmented villonodular synovitis associated with pathological fracture of the odontoid and atlantoaxial instability | PPigmented villonodular synovitis (PVNS) is a proliferative disorder of the synovium with a predisposition for the appendicular skeleton. Rarely PVNS can arise from the spine, where this disorder usually presents with localized or radicular pain secondary to involvement of the posterior elements. Th... | Atlantoaxial instability; Pigmented villonodular synovitis; Odontoid | 2007 |
| 15 |
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Schmidt, Meic H.; Brockmeyer, Douglas Lee; Dailey, Andrew T. | Surgical management of aneurysmal bone cysts of the spine | Object. Aneurysmal bone cysts of the spine are benign, highly vascular osseous lesions of unknown origin that may present difficult diagnostic and therapeutic challenges. They are expansile lesions containing thin-walled, blood-filled cystic cavities that cause bone destruction and sometimes spinal ... | Aneurysmal bone cyst; Spine tumor; Spinal fusion; Embolization | 2003 |
| 16 |
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Couldwell, William T. | Metastatic melanoma to the pituitary gland | Metastasis to the pituitary gland is unusual, and occurs most often in patients with carcinomas of the breast or lung. Despite its propensity for spread to the brain, metastatic melanoma has rarely been described within the sella. Methods: We report two cases of malignant melanoma pathologically co... | | 2007 |
| 17 |
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Couldwell, William T.; Osborne, Anne G. | Hypertrophic olivary degeneration after surgical removal of cavernous malformations of the brain stem: report of four cases and review of the literature | Background: Hypertrophic olivary degeneration (HOD) is a pathological phenomenon that occurs after injury to the dentato-olivary pathway. Its hallmarks include hypertrophy of the olive with increased T2 signal intensity on magnetic resonance imaging, and often manifests with palatal tremor and osci... | Hypertrophic olivary degeneration; Surgery; Cavernous malformation; Brainstem | 2008 |
| 18 |
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Couldwell, William T. | Multifocal inflammatory leukoencephalopathy associated with levamisole and 5-fluorouracil: case report | LEVAMISOLE AND 5-FLUOROURACIL have now become the standard chemotherapeutic regimen for patients with Stage 111 colon carcinoma. A case of multifocal inflammatory leukoencephalopathy secondary to levamisole alone or combination of levamisole and 5-fluorouracil is reported. Magnetic resonance imaging... | Autopsy; Levamisole; Multifocal inflammatory leukoencephalopathy | 1994 |
| 19 |
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Couldwell, William T. | Hypericin: a potential antiglioma therapy | HYPERICIN, A POLYCYCLIC aromatic dione isolated from plants, is presently being clinically evaluated as an antiviral agent in the treatment of human immunodeficiency virus (HIV) infection. In addition, it is known to be a potent protein kinase C inhibitor. To evaluate its potential as an inhibitor o... | Hypericin; Protein kinase C; Glioma; Brain neoplasm | 1994 |
| 20 |
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Couldwell, William T.; Gillespie, David L.; Jensen, Randy L. | Novel model of intracranial meningioma in mice using luciferase-expressing meningioma cells | Object. Meningioma research has been hindered by the inability to sequentially measure intracranial tumor growth in a cost-effective, efficient manner. Recently, the luciferase gene has been transfected into cancer lines to obtain cells that express the luciferase enzyme, which oxidizes luciferin in... | | 2008-01-01 |
| 21 |
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Garber, Sarah | Neurosurgical complications of direct thrombin inhibitors - catastrophic hemorrhage after mild traumatic brain injury in a patient receiving dabigatran | Dabigatran etexilate is an oral anticoagulant that acts as a direct, competitive thrombin inhibitor. Large randomized clinical trials have shown higher doses of dabigatran (150 mg taken twice daily) to be superior to warfarin in terms of stroke and systemic embolism rates in patients with nonvalvula... | | 2012-01-01 |
| 22 |
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Couldwell, William T. | Resolution of an anterior-inferior cerebellar artery feeding aneurysm with the treatment of a transverse-sigmoid dural arteriovenous fistula | The authors describe a 27-year old man who developed an unruptured anterior-inferior cerebellar artery feeding aneurysm from a transverse-sigmoid dAVF and its subsequent resolution with the treatment of the dAVF. The patient, with a known history of left transverse and sigmoid sinus thrombosis, pres... | Aneurysms; Dural Arteriovenous Fistulas; Endovascular therapy; Surgery | 2007 |
| 23 |
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Kestle, John R. W. | Lack of benefit of endoscopic ventriculoperitoneal shunt insertion: a multicenter randomized trial | Object. Endoscopically assisted ventricular catheter placement has been reported to reduce shunt failure in uncontrolled series. The authors investigated the efficacy of this procedure in a prospective multicenter randomized trial. Methods. Children younger than 18 years old who were scheduled for t... | Ventriculoperitoneal shunt; Shunt insertion; Shunt failure | 2003 |
| 24 |
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Kestle, John R. W. | Determining the best cerebrospinal fluid shunt valve design: the pediatric valve design trial | Myriad cerebrospinal fluid shunt valve designs are available (17, IS). None has ever been shown to be superior to another, although claims by neurosurgeons and shunt manufacturers of the merits of particular designs are numerous. Such is the case with two recent shunt valve designs, the Orbis-Sigm... | Pediatric valve design; Shunt valves | 1996 |
| 25 |
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Kestle, John R. W.; Walker, Marion L. | Noncommunicating spinal extradural arachnoid cyst causing spinal cord compression in a child | Extradural arachnoid cysts in the spine are relatively uncommon causes of spinal cord compression in the pediatric population that are thought to arise from congenital defects in the dura mater. Most reports describe such cysts communicating with the intrathecal subarachnoid space through a small de... | | 2006 |
