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Creator | Title | Description | Subject | Date |
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Kestle, John R. W. | Predicting shunt failure on the basis of clinical symptoms and signs in children | Object. In evaluating pediatric patients for shunt malfunction, predictive values for symptoms and signs are important in deciding which patients should undergo an imaging study, whereas determining clinical findings that correlate with a low probability of shunt failure could simplify management. ... | Pediatric Shunt Design Trial; PSDT; Shunt failure; Shunt malfunction; Clinical signs | 2001 |
2 |
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Couldwell, William T. | Definition of the role of contemporary surgical management in cisternal and parenchymatous cysticercosis cerebri | With increasing immigration from endemic regions, the incidence of neurocysticercosis in North America is rising. This retrospective study was undertaken to examine the role of surgery in those cases presenting with large cystic parenchymal and cisternal lesions in the current era of anthelminthic a... | Brain cyst; Computed tomography; Neurocysticercosis; Magnetic resonance imaging; Praziquantel; Stereotaxis | 1991 |
3 |
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Couldwell, William T. | Initial experience related to the use of the Cosman-Roberts-Wells stereotactic instrument | Initial experience with a new arc-radius design of stereotactic frame that interfaced with the existing components of the Brown-Roberts-Wells instrument is reported. Over a 6-month period, 32 procedures were performed on 23 males and nine female patients (mean age 32 years); these included 27 ster... | Image-directed stereotaxis; Stereotactic instrument; Cosman-Roberts-Wells stereotaxy | 1990 |
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Couldwell, William T. | Management of cysticercosis cerebri | Infestation of the central nervous system (CNS) with the parasitic larval form of the cestode Taenia solium, Cysticercosis Cerebri represents an endemic problem in much of the underdeveloped world. In such areas, up to 4% of the population maybe affected by neurocysticercosis, and it accounts for u... | Taenia solium; Cysticercosis Cerebri; Parenchymal cyst; Basilar cisternal cyst; Intraventricular cyst | 1989 |
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Kestle, John R. W. | Ventriculoperitoneal shunts in children: indications, equipment and techniques | The decision to implant a ventriculoperitoneal shunt in a child with ventriculomegaly should not be taken lightly. Once a shunt has been implanted, it is very difficult to determine that it is no longer necessary, and therefore the initial decision is very important. Sometimes the need is obvious, s... | | 2008 |
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Kestle, John R. W. | Lack of benefit of endoscopic ventriculoperitoneal shunt insertion: a multicenter randomized trial | Object. Endoscopically assisted ventricular catheter placement has been reported to reduce shunt failure in uncontrolled series. The authors investigated the efficacy of this procedure in a prospective multicenter randomized trial. Methods. Children younger than 18 years old who were scheduled for t... | Ventriculoperitoneal shunt; Shunt insertion; Shunt failure | 2003 |
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Kestle, John R. W. | Significance of bacteriologically positive ventriculoperitoneal shunt components in the absence of other signs of shunt infection | The purpose of this study was to determine the significance of "asymptomatic bacteriological shunt contamination" (ABSC), defined as a positive bacteriological culture found on a ventricular shunt component in the absence of bacteria in the cerebrospinal fluid (CSF) culture and/or clinical evidence ... | Ventricular shunt; Shunt infection; Ventriculoperitoneal shunt; Asymptomatic bacteriological; Shunt contamination | 1996 |
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Couldwell, William T. | Experience with use of extended length peritoneal shunt catheters | The placement of a ventriculoperitoneal (VP) shunt is the current treatment of choice for diversion of cerebrospinal fluid associated with hydrocephalus. Although there are a host of reported potential abdominal complications related to the procedure, they are notably uncommon. The authors report t... | | 1996 |
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Kestle, John R. W. | Randomized trial of cerebrospinal fluid shunt valve design in pediatric hydrocephalus | OBJECTIVE: Forty percent of standard cerebrospinal fluid shunts implanted for the treatment of pediatric hydrocephalus fail within the first year. Two new shunt valves designed to limit excess flow, particularly in upright positions, were studied to compare treatment failure rates with those for st... | Shunt failure; Valve design; Orbis-Sigma valve; Delta valve | 1998 |
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Kestle, John R. W. | Late rapid deterioration after endoscopic third ventriculostomy: additional cases and review of the literature | Object. Late rapid deterioration after endoscopic third ventriculostomy (ETV) is a rare complication. The authors previously reported three deaths from three centers. Three other deaths and a patient who experienced rapid deterioration have also been reported. Following the death at the University ... | Endoscopic third ventriculostomy; ETV; Pediatric neurosurgery; Adverse outcome | 2006 |
11 |
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Couldwell, William T.; House, Paul A.; Salzman, Karen L.; Osborne, Anne G.; MacDonald, Joel D.; Jensen, Randy L. | Surgical considerations regarding giant dilations of the perivascular spaces | Object. Dilations of brain perivascular spaces (PVSs), also known as Virchow-Robin spaces, are routinely identified on magnetic resonance imaging studies of the brain and recognized as benign normal variants. Giant dilations occur only rarely and can be easily misdiagnosed as central nervous system ... | | 2004 |
12 |
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Couldwell, William T. | Immunology and immunotherapy of intrinsic glial tumors | Immunological aspects of glial neoplasms have been actively investigated for the past several years with particular focus on academic, diagnostic, and therapeutic objectives. As more knowledge is acquired about the cellular events relating to tumor behavior the more it appears that the immune system... | Immunology; Glial tumors | 1990 |
13 |
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Couldwell, William T. | Malignant glioma-derived soluble factors regulate proliferation of normal adult human astrocytes | Malignant gliomas are characteristically surrounded by marked gliosis. To assess whether glioma-derived products contribute to the proliferation of astrocytes, a feature of the gliosis response, we evaluated the influence of culture supernatants from malignant human glioma lines and tumor cyst fluid... | Astrocyte; Glioma; Gliosis; Proliferation; Soluble factors | 1992 |
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Kestle, John R. W.; Simon, Tamara Danielle | Infection rates following initial cerebrospinal fluid shunt placement across pediatric hospitals in the United States | Object. Reported rates of CSF shunt infection vary widely across studies. The study objective was to determine the CSF shunt infection rates after initial shunt placement at multiple US pediatric hospitals. The authors hypothesized that infection rates between hospitals would vary widely even after ... | Shunt placement; Pediatric neurosurgery | 2009 |
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Kestle, John R. W.; MacDonald, Joel D.; Schmidt, Richard H. | Marked reduction of cerebral vasospasm with lumbar drainage of cerebrospinal fluid after subarachnoid hemorrhage | Object. Cerebral vasospasm after subarachnoid hemorrhage (SAH) continues to be a major source of morbidity in patients despite significant clinical and basic science research. Efforts to prevent vasospasm by removing spasmogens from the subarachnoid space have produced mixed results. The authors hyp... | Cerebral vasospasm; Lumbar drainage | 2004 |
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Couldwell, William T. | Resident curriculum guidelines for neurosurgery | This curriculum was created to detail the body of knowledge that should be attained by an individual completing residency training in neurological surgery. The specific structure of resident education in neurological surgery is defined by the American Board of Neurological Surgery, and each program... | Residency training; Neurological surgery | 2000 |