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1 Garber, SarahNeurosurgical complications of direct thrombin inhibitors - catastrophic hemorrhage after mild traumatic brain injury in a patient receiving dabigatranDabigatran etexilate is an oral anticoagulant that acts as a direct, competitive thrombin inhibitor. Large randomized clinical trials have shown higher doses of dabigatran (150 mg taken twice daily) to be superior to warfarin in terms of stroke and systemic embolism rates in patients with nonvalvula...2012-01-01
2 Couldwell, William T.Response to Craniopharyngioma adherence to the hypothalamusTo The Editor: We have viewed with great interest the special supplement published by Neurosurgical Focus in January 2013 (Neurosurgical Focus, Video Atlas of Operative Surgery: Intraventricular Lesions: Microscopic and Endoscopic Approaches, Vol 34: January 2013) in which a compilation of videos de...2014-01-01
3 Couldwell, William T.Sellar and parasellar metastatic tumorsThe sellar and parasellar (SPS) region is a complex area rich in vital neurovascular structures a first manifestation of a systemic malignancy. Metastases to this region are rare; breast cancer is the most common source among those that metastasize to the SPS region. Ophthalmoplegia, headache, retro...2012-01-01
4 Jensen, Randy LynnTreatment-related brain tumor imaging changes: so-called "pseudoprogression" vs. tumor progression: Review and future research opportunitiesBackground: Glioblastoma multiforme (GBM) has a dismal prognosis despite aggressive therapy. Initial diagnosis and measurement of response to treatment is usually determined by measurement of gadolinium-enhanced tumor volume with magnetic resonance imaging (MRI). Unfortunately, many GBM treatment mo...2013-01-01
5 Couldwell, William T.Transnasal excerebration surgery in ancient Egypt: Historical vignetteAncient Egyptians were pioneers in many fields, including medicine and surgery. Our modern knowledge of anatomy, pathology, and surgical techniques stems from discoveries and observations made by Egyptian physicians and embalmers. In the realm of neurosurgery, ancient Egyptians were the first to elu...2012-01-01
6 Couldwell, William T.Transtemporal approach to the removal of a lateral pontine tumorThis video demonstrates a very useful trajectory to a pontine lesion. A 68-year-old man presented with tongue numbness and weakness. The approach used was a transtemporal presigmoid retrolabyrinthine approach to enable an orthogonal trajectory to the lateral pons. Following the transtemporal opening...2014-01-01
7 Couldwell, William T.Intracranial hypotension as a complication of lumbar puncture prior to elective aneurysm clippingBackground: Lumbar dural defects are an uncommon but important cause of persistent intracranial hypotension in the neurosurgical population. We present a case of intracranial hypotension after elective craniotomy due to a lumbar puncture performed 3 weeks earlier. Case Description: A 55‑year‑old...2014-01-01
8 Couldwell, William T.Intracranial hypotension in the setting of concurrent perineural cyst rupture and subarachnoid hemorrhageAlthough most patients with intracranial hypotension typically present with headaches, the rest of the clinical spectrum is characteristically non-specific and often quite variable. In a patient with concurrent pathologies that can produce a similar clinical picture, a high index of suspicion must b...2013-01-01
9 Couldwell, William T.Intraoperative aneurysmal subarachnoid hemorrhage after rupture of a previously undiagnosed intracranial aneurysm during Chiari decompression: case report and literature reviewType 1 Chiari malformation occurs when caudal displacement of cerebellar tonsils below the level of foramen magnum obstructs the normal flow of cerebrospinal fluid (CSF) between the cranial and spinal spaces, a condition that often needs surgical decompression to restore normal CSF circulation. Abru...2014-01-01
10 Couldwell, William T.Management of meningiomas involving the transverse or sigmoid sinusMeningiomas that invade the transverse or sigmoid sinuses are uncommon tumors that are challenging to treat surgically. Although the risk of recurrence is associated with the extent of resection, complete removal of meningiomas in these locations must be balanced with avoidance of venous outflow obs...2013-01-01
11 Couldwell, William T.Efficacy of clip-wrapping in treatment of complex pediatric aneurysmsPurpose: Pediatric aneurysms (PAs) are distinct from their adult counterparts with respect to typical location, aneurysm type, and known predisposing risk factors. Many strategies have been employed to treat PAs, but, although it has been used frequently in adults, clip-wrapping in pediatric patient...2012-01-01
12 Couldwell, William T.Giant pituitary tumor combined approachNishioka et al. have provided a review of 29 patients with large pituitary adenomas who underwent surgery through a simultaneous transsphenoidal and transcranial approach at their institution during a 7-year period. Large adenomas with hourglass constriction, complex lobulations, and asymmetric exte...2012-01-01
13 Dailey, Andrew T.Lateral mass screw fixation in the cervical spineTo The Editor: We read with interest the article by Kawabata et al.15 (Kawabata S, Watanabe K, Hosogane N, et al: Surgical correction of severe cervical kyphosis in patients with neurofibromatosis Type 1. Report of 3 cases. J Neurosurg Spine 18:274-279, March 2013). Reconstructive spinal surgery has...2014-01-01
14 Patel, Bhupendra C.Lateral orbital wall approach to the cavernous sinus: laboratory investigationObject. Lesions of the cavernous sinus remain a technical challenge. The most common surgical approaches involve some variation of the standard frontotemporal craniotomy. Here, the authors describe a surgical approach to access the cavernous sinus that involves the removal of the lateral orbital wal...2012-01-01
15 Schmidt, Meic H.Isolated intramedullary neurosarcoidosis of the thoracic spine: case report and review of the literatureSarcoidosis can involve the central nervous system in approximately 5-15% of cases. Any part of the nervous system can be involved, so presentation can be quite varied. Isolated disease of the spinal cord is even less common and reports are limited to single cases and small series. Although in the s...2012-01-01
16 Schmidt, Meic H.Is vertebral augmentation the right choice for cancer patients with painful vertebral compression fractures?Cancer-related fractures of the spine are different from osteoporotic ones, not only in pathogenesis but also in natural history and treatment. Higher class evidence now supports offering balloon kyphoplasty to a patient with cancer, provided that the pain is significant in intensity, has a position...2012-01-01
17 Dailey, Andrew T.; Brodke, Darrel S.Inter- and intraobserver reliability of computed tomography in assessment of thoracic pedicle screw placementStudy Design. Reliability study of computed tomography imaging in 12 cadaver specimens instrumented with titanium or stainless steel thoracic pedicle screws. Objective. To evaluate inter- and intraobserver reliability of computed tomography scan in determining the accuracy of thoracic pedicle sc...Thoracic pedicle screw; Placement; Assessment; Computed tomography2003
18 Dailey, Andrew T.Magnetic resonance neurography for cervical radiculopathy: a preliminary reportMAGNETIC RESONANCE NEUROGRAPHY was used to directly image cervical spinal nerves in patients with clinical and radiographic evidence of cervical radiculopathy. A magnetic resonance imaging phased-array coil system was used to obtain high-resolution coronal T1-weighted spin echo, coronal/axial T2-wei...1996
19 Couldwell, William T.Practicing neurosurgery in the United StatesCompared with other developed countries, the U.S. spends a high percentage of its gross domestic product on healthcare: 16 percent in 2005, up from 15 percent in 2004. This is far and away the greatest percentage of GDP spent on healthcare of any nation for which such data is collected. However,...2008-01-01
20 Dailey, Andrew T.Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 11: interbody techniques for lumbar fusionStandards. There is insufficient evidence to recommend a treatment standard. Guidelines. In the context of a single-level stand-alone ALIF or ALIF with posterior instrumentation, the addition of a PLF is not recommended as it increases operating room time and blood loss without influencing the like...Fusion; Lumbar spine; Degenerative disease; Lumbar fusion; Interbody techniques2005
21 Couldwell, William T.Radiographic features of tumefactive giant cavernous angiomasGiant cavernous angiomas (GCAs) are very rare, and imaging features of GCAs can be very different from those of typical cavernous angiomas (CAs), making them a diagnostic challenge. The purpose of the study was to evaluate the radiographic features of GCAs, with an emphasis on the differentiating fe...Cavernous angiomas; Cavernous malformations; Tumefactive2008
22 Couldwell, William T.Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifenPREVIOUS WORK HAS demonstrated the importance of the Protein Kinase C (PKC) signal transduction system in regulating the growth rate of malignant gliomas in vitro. Tamoxifen inhibits PKC in a minority of malignant gliomas within the micromolar concentration range in vitro, a property distinct from...Tamoxifen; Protein kinase C; Glioma; Brain neoplasm; Chemotherapy; Glioma1993
23 Dailey, Andrew T.Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 5: correlation between radiographic and functional outcomeStandards. There is insufficient evidence to recommend a treatment standard. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. It is recommended that when performing lumbar arthrodesis for degenerative lumbar disease, strategies to achieve successful radiogr...Lumbar fusion; Lumbar spine; Degenerative disease; Practice guidelines; Functional outcome; Radiographic outcome2005
24 Kestle, John R. W.Late rapid deterioration after endoscopic third ventriculostomy: additional cases and review of the literatureObject. Late rapid deterioration after endoscopic third ventriculostomy (ETV) is a rare complication. The authors previously reported three deaths from three centers. Three other deaths and a patient who experienced rapid deterioration have also been reported. Following the death at the University ...Endoscopic third ventriculostomy; ETV; Pediatric neurosurgery; Adverse outcome2006
25 Couldwell, William T.The frontotemporal (Pterional) approach: an historical perspectiveThe frontotemporal, so-called "pterional" approach has evolved with the contribution of many neurosurgeons over the past century. It has stood the test of time and been the most commonly used transcranial approach in neurosurgery. In its current form, drilling the sphenoid wing as far down as the su...2012-01-01
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