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1 Huang, Lin EricHIF-1? mediates tumor hypoxia to confer a perpetual mesenchymal phenotype for malignant progressionAlthough tumor progression involves genetic and epigenetic alterations to normal cellular biology, the underlying mechanisms of these changes remain obscure. Numerous studies have shown that hypoxia-inducible factor 1? (HIF-1?) is overexpressed in many human cancers and up-regulates a host of hypoxi...
2 Couldwell, William T.Sellar and parasellar metastatic tumorsThe sellar and parasellar (SPS) region is a complex area rich in vital neurovascular structures a first manifestation of a systemic malignancy. Metastases to this region are rare; breast cancer is the most common source among those that metastasize to the SPS region. Ophthalmoplegia, headache, retro...2012-01-01
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