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Creator | Title | Description | Subject | Date |
1 |
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Capecchi, Mario R. | Male fertility is dependent on dipeptidase activity of testis ACE. | Testis angiotensin-converting enzyme (ACE) is an isozyme exclusively expressed by developing sperm. This protein has only a single catalytic domain containing the HEXXH consensus-site motif typical of zinc metallopeptidases. The exact role of testis ACE is unknown, but male mice lacking the protein ... | Amino Acid Motifs; Blotting, Western; Catalytic Domain; Comparative Study; Isoenzymes; Protein Structure, Tertiary | 2005-11-11 |
2 |
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Gesteland, Raymond F.; Baranov, Pavel V.; Atkins, John F. | Expression levels influence ribosomal frameshifting at the tandem rare arginine codons AGG_AGG and AGA_AGA in Escherichia coli | ABSTRACT: The rare codons AGG and AGA comprise 2% and 4%, respectively, of the arginine codons of Escherichia coli K-12, and their cognate tRNAs are sparse. At tandem occurrences of either rare codon, the paucity of cognate aminoacyl tRNAs for the second codon of the pair facilitates peptidyl-tRNA... | Gene expression; Frameshifting; E. coli; Arginine codons | 2005 |
3 |
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Rogers, Alan R.; Jorde, Lynn B. | Origins and affinities of modern humans: a comparison of mitochondrial and nuclear genetic data | To test hypotheses about the origin of modern humans, we analyzed mtDNA sequences, 30 nuclear restriction-site polymorphisms (RSPs), and 30 tetranucleotide short tandem repeat (STR) polymorphisms in 243 Africans, Asians, and Europeans. An evolutionary tree based on mtDNA displays deep African branch... | Base Sequence; Variation (Genetics); Base Sequence | 1995 |
4 |
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Rogers, Alan R.; Harpending, Henry C. | Genetic structure of ancient human populations | Discusses mitochondrial DNA (mtDNA) sequences as important source of data about the history of human species. | Tree of descent; Mismatch distributions; Simulations; Findings; Intermatch distributions; Younger and older populations | 2001-09-15 |