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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Gesteland, Raymond F.; Atkins, John F.; Baranov, Pavel V. | Diverse bacterial genomes encode an operon of two genes, one of which is an unusual class-I release factor that potentially recognizes atypical mRNA signals other than normal stop codons | ABSTRACT: Background: While all codons that specify amino acids are universally recognized by tRNA molecules, codons signaling termination of translation are recognized by proteins known as class-I release factors (RF). In most eukaryotes and archaea a single RF accomplishes termination at all three... | Class-I release factors; RF1; RF2; Bacterial genomes | 2006 |
| 2 |
 | Gesteland, Raymond F.; Atkins, John F. | Evolutionary specialization of recoding: frameshifting in the expression of S. cerevisiae antizyme mRNA is via an atypical antizyme shift site but is still +1 | An autoregulatory translational shift to the +1 frame is required for the expression of ornithine decarboxylase antizyme from fungi to mammals. In most eukaryotes, including all vertebrates and a majority of the studied fungi/yeast, the site on antizyme mRNA where the shift occurs is UCC-UGA. The me... | Antizyme; ODC; Polyamines; Frameshifting | 2006 |
| 3 |
 | Hansen, Mark S.; Healy, Lindsey J.; Johnson, Christopher R.; Capecchi, Mario R.; Keller, Charles; Jones, Greg M. | Virtual histology of transgenic mouse embryos for high-throughput phenotyping. | A bold new effort to disrupt every gene in the mouse genome necessitates systematic, interdisciplinary approaches to analyzing patterning defects in the mouse embryo. We present a novel, rapid, and inexpensive method for obtaining high-resolution virtual histology for phenotypic assessment of mouse ... | Forkhead Transcription Factors; Paired Box Transcription Factors | 2006 |
| 4 |
 | Lopansri, Bert; Stoddard, Gregory J.; Hobbs, Maurine R.; Granger, Donald Lee | Elevated plasma phenylalanine in severe malaria and implications for pathophysiology of neurological complications. | Cerebral malaria is associated with decreased production of nitric oxide and decreased levels of its precursor, l-arginine. Abnormal amino acid metabolism may thus be an important factor in malaria pathogenesis. We sought to determine if other amino acid abnormalities are associated with disease sev... | Dystonia; Phenylalanine Hydroxylase; Tyrosine | 2006-06-01 |
| 5 |
 | Rogers, Alan R. | How much can fossils tell us about regional continuity? | Presents a study on the genetic contribution of earlier populations to later populations within regions called regional continuity. Testing for regional continuity with multiple characters; Replacement of archaic population by a population of modern humans. | Human genetics; Fossils; Regional continuity | 2006-06-05 |
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