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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |  | Capecchi, Mario R. | Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy. | Although the role of Hox genes in patterning the mammalian body plan has been studied extensively during embryonic and fetal development, relatively little is known concerning Hox gene function in adult animals. Analysis of mice with mutant Hoxa9, Hoxb9, and Hoxd9 genes shows that these paralogous g... | Embryonic and Fetal Development; Gene Expression Regulation, Developmental; Genotype; Mice, Knockout | 1999-01 |
| 2 |  | Capecchi, Mario R.; Bernstein, Kenneth E.; Thomas, Kirk R. | Targeting genes for self-excision in the germ line | A procedure is described that directs the self-induced deletion of DNA sequences as they pass through the male germ line of mice. The testes-specific promoter from the angiotensin-converting enzyme gene was used to drive expression of the Cre-recombinase gene. Cre was linked to the selectable marker... | Cre-recombinase; Hoxa3; Chimeric mice | 1999-06-15 |
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