Creator | Title | Description | Subject | Date | ||
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1 | Fan, Huijun | Examination of Y-Deterium isotope effects for the solvolysis of model isoprenoid compounds | Model isoprenoid compounds can undergo two distinct pathways, dissociative or associative nucleophilic substitution depending on the conditions used. The dissociative pathway consists of two steps, involving a carbocation intermediate where the formation of that carbocation is rate determining. The ... | Isopentenoids; Solvolysis; Deuterium - Isotopes | 2012-05 | |
2 | Odendahl, Nathan | Comparison of popular force fields for molecular modeling of proteins applied to ice binding of the tenebrio molitor antifreeze protein | Ice Binding Proteins (IBPs) are a class of proteins that affect the melting and freezing temperatures of ice. While substantial research has been conducted to understand the properties of IBPs, experimental and molecular dynamics simulations have not satisfactorily explained the mechanism of the i... | Antifreeze proteins - Research; Ice binding proteins; Tenebrio molitor; Antifreeze protein; Force fields | 2016-04 | |
3 | Franchina, Jordan Avery | Measurement of bond dissociation energies of transition metal molecules | Measuring thermochemical and kinetic properties of chemical systems has always; been a central theme of chemistry. Knowing these properties assists us in assessing; whether or not a chemical reaction is energetically feasible, efficient, and worthwhile.; Theoretical chemistry has now developed suffi... | Chemical systems; thermochemical; kinetic; modeling | 2018-04 | |
4 | Khuu, Scott | Identifying Retinoic Acid Dependent Mechanisms of Neural Crest Epithelial-Mesenchymal Transition | Cancer metastasis is one of the distinguishing traits that make the disease difficult to treat. The steps of tumor invasion are similar to a process called epithelial to mesenchymal transition (EMT). Retinoic acid (RA) is shown to inhibit EMT and may cause an increased transcription of the gene, ski... | 2017 | ||
5 | Kent, Alexandra | DNA split aptamers as a biosensing platform for the detection of small drug molecules | Prescription drug overdose and abuse is a leading cause of death in the United States. It is a serious issue and has become increasingly problematic as opioids are being prescribed with a higher frequency. For this reason, fast, accurate detection of small drug molecules is crucial. The current stan... | Drug testing; Biosensors; DNA split aptamers | ||
6 | Burga, Carlos Alberto | Binary superlattices of semiconductor nanocrystals : a path towards possible high-temperature superconductivity | This thesis provides a platform to experimentally test Dr. Daniel Mattis' theoretical work on the possible superconductive behavior of nanostructured intrinsic semiconductors1-2. The theoretical work hinged on the nano-scale architecture of semiconductors. Therefore, using various types of semicondu... | Semiconductor nanocrystals; Superconductivity; Superlattices as materials | 2013-05 | |
7 | Walker, Kortnie | Understanding and treating diabetic retinopathy | Diabetic retinopathy is a neurovascular disease of the retina and is the leading cause of blindness in the working-age population in the United States. Complications as a result of hyperglycemia and diabetes mellitus (DM) break down the blood-retina barrier (BRB) and retinal vasculature. Current tre... | Diabetic retinopathy | 2015-05 |