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| Creator | Title | Description | Subject | Date | ||
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Kendell, Isaac | Immunomodulation improves cancer cell clearance by T cells during multi-antigent T cell hybridizer therapy | Treatment of hematopoietic malignancies is challenging due to systemic side effects of current treatments and the possibility of relapse. Multi-antigen T cell hybridizer (MATCH) therapy is a novel treatment system composed of antibody fragments conjugated with morpholino oligonucleotides, which hybr... | 2024 | |
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Vetter, Mikey | Inhibition of FAK and AKT as potential therapies for melanoma brain metastasis | Brain metastasis is the leading cause of death in patients with advanced melanoma. Melanoma diagnoses nearly reached 100,000 in 2019, and melanoma patients make up 10% of all patients with brain metastasis [1]. The roles of the mitogen-activated protein kinase (MAPK) pathway and the phosphatidylinos... | vehicle control; previously | 2021 |
| 3 |
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Hyer, Christina Cottrell | Effect of M1 Matrix Protein on Hemagglutinin Expression and Influenza Virus-Like Particle Production in Trichoplusia NI | Virus-like particles (VLPs) are a new and effective flu vaccine approach. VLPs are non-infectious and can produce robust immune responses. Flu VLPs are typically created by co-expressing the flu hemagglutinin (HA) surface antigen and the matrix protein M1-which assists in viral and VLP budding-in cu... | 2017 | |
| 4 |
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Slominski, Emma N. | Comparison of transcranial MR-guided focused ultrasound phase correction simulations to clinically measured MRTI | Essential tremor and Parkinson's disease are neurological disorders causing involuntary shaking that affects an estimated 8 million people in the United States. Transcranial Magnetic Resonance-guided Focused Ultrasound (tcMRgFUS) is a noninvasive alternative method of treating tremors to the invasiv... | 2021 | |
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Armstrong, Blair P. | Lower critical solution temperature behavior of elastin-coiled-coil polymer, a potential platform for treatment of non-hodgkin's lymphoma | Non-Hodgkin's lymphoma takes the lives of 20,000 Americans each year. When traditional therapies fail, clinicians have turned to a drug, rituximab, for treatment. However, rituximab is now curative for less than 50% of patients and new treatments are needed. Drug-free macromolecular therapeutics (DF... | 2021 | |
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Frederiksen, Hunter | Pharmacokinetics of Locally Delivered Vancomycin as a Powder & in a Hydrogel | Orthopedic surgeons currently administer powder vancomycin directly over surgical sites in order to mitigate infections. Local antibiotic administration has been effective at reducing infections; however, there have been few preliminary studies investigating the pharmacokinetics of locally delivered... | 2018 |
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