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Creator | Title | Description | Subject | Date |
101 |
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Scamfer, Sierra | Studying pancreatic acinar cell differentiation through transcription factor reprogramming | Pancreatic ductal adenocarcinoma is a highly lethal human cancer that originates from acinar cells in the pancreas. Ptf1a is a transcription factor that plays an important role in the development of the pancreas and in the differentiation and maintenance of acinar cells. Ptf1a expression is lost dur... | | 2021 |
102 |
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Enriquez, Trisha Pauline Diaz | Substrate use within the drosophila melanogaster species subgroup | Effective sensory perception is a vital aspect of survival for living organisms such as Drosophila. More specifically, olfaction, or the sense of smell, is essential because the detection of odors allows it to find potential food, danger, or specifically, where to lay eggs. This review will examine ... | | 2021 |
103 |
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Watkins, Ryan Davis | Suppression of lymphangiogenesis using VEGF-C trap | The lymphatic system is responsible for controlling systemic fluid buildup. Lymphangiogenesis is a dynamic process involving sprouting, and maintaining new lymphatic vasculature. Vascular endothelial growth factor C (VEGF-C) is as a key growth factor that induces lymphangiogenesis by binding VEGF re... | Lymphatics - Growth; Vascular endothelial growth factors - Antagonists; Lymphangiogenesis; VEGF-C trap | 2014-05 |
104 |
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Rowe, Ana Bruns | The suppression of signal-switching defects in the Escherichia coli serine chemoreceptor | The model bacterium Escherichia coli contains a chemotaxis system that allows the cell to change its swimming behavior in response to its environment. As the cell swims, transmembrane chemoreceptors detect concentration changes in attractant and repellent compounds and transmit signals across the in... | | 2023 |
105 |
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Domagala, Drue | Synthesis of protacs to inhibit toll-like receptors | The immune system is the body's defense against pathogens. Since it has to be able to withstand the fast-evolving nature of microscopic invaders, the immune system has a variety of mechanisms to recognize and destroy them. One way that pathogens are recognized is through toll-like receptor (TLR) sig... | | 2022 |
106 |
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Judd, David Paul | Telomere proteins of Drosophila melanogaster: HipHop and MSK81 | DNA molecules encoding two proteins, HipHop and MSK81, were cloned into bacteria so as to make large amounts of these proteins that bind to telomeres of Drosophila (fruit fly) chromosomes. The goal was to determine whether known DNA binding motifs are present in HipHop and MSK81. Understanding how t... | Biology | 2012-05 |
107 |
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Roestenburg, Jessica | Testing the Perceptual Salience of Spectral Content in Zebra Finch Song | Birds actively adjust the resonance properties of the upper vocal tract during singing, which results in specific harmonic structures of song elements. To what degree upper vocal tract filtering is relevant for the perceptual salience of song is poorly understood. This research utilizes (1) a biolog... | | 2018 |
108 |
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Woodruff, Derek | Uncovering Synaptic Defects resulting from loss of the intellectual disability and autism-associated gene Kirrel3 | Neurodevelopmental disorders severely impact an individual's life. Surprisingly, the genetic and cellular cause of over half of intellectual disability cases and more than 80% of autism spectrum disorders remain undiscovered1,2. It is likely that mutations in molecules regulating synapse development... | | 2017 |
109 |
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Amaechi, Ayana | Understanding sex differences in early predictors of pathological aggression with a mouse model | Antisocial behavior (ASB) is characterized by aggression, violence, drug use, thrillseeking behavior, and delinquent behavior. While childhood and adolescent maltreatment contribute to the ontogeny of this condition, converging evidence suggests that genetic factors play an equally important role. T... | MAOA; pathological aggression; sex differences; stress; early development; animal models | 2021 |
110 |
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Lee, Zachary | Using Drosophila to investigate p53 life-or-death decisions | The p53 tumor suppressor is a central regulator of cellular responses to DNA damage. When DNA damage cannot be repaired most cells undergo p53-dependent cell death. Thisp55-mediated apoptosis is important to eliminate cells with damaged genomes and provides an important block to the development of c... | Biology | 2013-05 |
111 |
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Som, Sarita | Virus-like weapons used for competition in wild plant populations | Plant diseases caused by bacterial pathogens pose significant economic challenges globally, necessitating the exploration of alternative methods for controlling bacterial infections in plants. Tailocins, virus-like weapons produced by bacteria, have emerged as potent antibacterial agents and hold po... | | 2023 |
112 |
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Checketts, Cynthia | Why white mice? improving biological literacy through animal history | Throughout the undergraduate experience, biology students are introduced to hundreds of experiments, theories, and principles, many of which are rooted in animal experimentation. However, in required and information-heavy biology courses, the erasure of animals from the scientific story-which repres... | | 2021 |