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Creator | Title | Description | Subject | Date |
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Johnson, KariAnne Rencher | Identification of PASK substrates and/or interacting proteins | PAS kinase (PASK) is an evolutionary conserved serine/threonine kinase that appears to have a role in the regulation of cellular energy metabolism. It has previously been shown that mice lacking PASK (PASK"/_ mice) are resistant to the development of hepatic steatosis (lipid accumulation in the live... | Biology | 2012-05 |
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Judd, David Paul | Telomere proteins of Drosophila melanogaster: HipHop and MSK81 | DNA molecules encoding two proteins, HipHop and MSK81, were cloned into bacteria so as to make large amounts of these proteins that bind to telomeres of Drosophila (fruit fly) chromosomes. The goal was to determine whether known DNA binding motifs are present in HipHop and MSK81. Understanding how t... | Biology | 2012-05 |
3 |
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Lee, Zachary | Using Drosophila to investigate p53 life-or-death decisions | The p53 tumor suppressor is a central regulator of cellular responses to DNA damage. When DNA damage cannot be repaired most cells undergo p53-dependent cell death. Thisp55-mediated apoptosis is important to eliminate cells with damaged genomes and provides an important block to the development of c... | Biology | 2013-05 |