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CreatorTitleDescriptionSubjectDate
1 Baehr, WolfgangTissue-specific expression in transgenic mice directed by the 5'-flanking sequences of the human gene encoding interphotoreceptor retinoid-binding proteinInterphotoreceptor retinoid-binding protein (IRBP) is an extracellular protein that has been suggested to participate in the visual process as a carrier for visual retinoids. A chimeric gene composed of the human IRBP promoter fused to the bacterial reporter gene chloramphenicol acetyltransferase (C...Restriction Mapping; Nucleic Acid Hybridization; Mice; Gene Expression1990-05-25
2 Bastiani, MichaelLoss of axons in the cat optic nerve following fetal unilateral enucleation: an electron microscopic analysisBetween the 48th day of gestation (E-48) and maturity, the number of axons in the cat optic nerve is reduced by approximately 50%. On the basis of an electron microscopic assay, the axon population of the E-48 nerve was estimated to be 328,000. In contrast, estimates from two normal adults were 159,...Ganglion cell death; Retinofugal projection; Retinal ganglion cell axons1983
3 Jorgensen, ErikNeural plasticityNeural plasticity refers to functional changes in the nervous system and therefore encompasses a range of phenomena from changes at synapses observed on a microscopic scale to changes in behavior observed in the whole animal. These diverse phenomena are related since changes in synapses are believ...Synapses; Nervous System; Development1997
4 Jorgensen, ErikCaenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic developmentThe neurotransmitter GABA has been proposed to play a role during nervous system development. We show that the Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase (GAD), the GABA biosynthetic enzyme. unc-25 is expressed specifically in GABAergic neurons. Null mutations in unc-25...1999
5 Olivera, Baldomero M.Identification and characterization of a Ca2+-sensitive nonspecific cation channel underlying prolonged repetitive firing in Aplysia neuronsThe afterdischarge of Aplysia bag cell neurons has served as a model system for the study of phosphorylation-mediated changes in neuronal excitability. The nature of the depolarization generating the afterdischarge, however, has remained unclear. We now have found that venom from Conus textile trig...Ca21-activated nonspecific cation channel; Slow inward current; Ion channel modulation; Afterdischarge; Bursting; Aplysia bag cell neurons; Conus textile; Neurotoxins1996
6 Bastiani, MichaelPathfinding by neuronal growth cones in grasshopper embryos: II. Selective fasciculation onto specific axonal pathwaysIn the previous paper (Raper, J. A., M. Bastiani, and C. S. Goodman (1983) J. Neurosci. 3: 20-30) we showed that the growth cones of two sibling neurons, the G and C cells, follow the same route in the developing grasshopper neuropil until they reach a stereotypic choice point. Here their growth con...Neurons; Axons; Neuropil1983
7 Yamaguchi, AyakoCoding rate and duration of vocalizations of the frog , Xenopus laevisVocalizations involve complex rhythmic motor patterns, but the underlying temporal coding mechanisms in the nervous system are poorly understood. Using a recently developed whole-brain preparation from which "fictive" vocalizations are readily elicited in vitro, we investigated the cellular basis of...2012-08-29
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