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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
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Coley, Phyllis D. | New cytotoxic cinnamic acid derivatives from leaves of Bonamia trichantha | Bioassay-guided fractionation of the methanolic extract of the young leaves of Bonamia trichantha led to the isolation of four new cinnamic acid derivatives trichanthins A-D (l-4).Their structures were established by spectroscopic methods. All compounds were tested in cytotoxic assays against the MC... | Bonamia trichantha; Cinnamic acid; Caffeic acid ester; p-Coumaric acid ester: Farnesol; Z-(l l)-hexadecen-l-ol; Cytotoxicity | 2006 |
| 2 |
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Olivera, Baldomero M. | Pyridine nucleotide metabolism in Escherichia coli. II. Niacin starvation | The effect of niacin starvation has been studied in a niacin-requiring auxotroph of Escherichia coli. If a culture is totally deprived of niacin, cells continue to divide until the total pyridine nucleotide content has fallen from 1.9 X 10^6 to 1.2 X 10^5 molecules per cell. During starvation, the r... | Starvation; Nicotinic acid | 1973 |
| 3 |
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Olivera, Baldomero M.; Zhang, MinMin; Azam, Layla; Yoshikami, Doju; Bulaj, Grzegorz | Structure/function characterization of μ-Conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels | Peptide neurotoxins from cone snails continue to supply compounds with therapeutic potential. Although several analgesic conotoxins have already reached human clinical trials, a continuing need exists for the discovery and development of novel nonopioid analgesics, such as subtype-selective sodium c... | Conotoxins; 956;-Conotoxin KIIIA; Neuronal blocker; Neurotoxins; Sodium channel blockers | 2007 |
| 4 |
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Olivera, Baldomero M. | Stapling mimics noncovalent interactions of γ-carboxyglutamates in conantokins, peptidic antagonists of N-methyl-D-aspartic acid receptors | Background: Can dicarba bridges (stapling) replace noncovalent interactions that stabilize helical conformation of neuroactivepeptides? Results: A rational design, synthesis, structural, and functional characterization of stapled conG analogs that target NMDAreceptors is reported. Conclusion: Staple... | 2012-01-01 | |
| 5 |
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Yamaguchi, Ayako | Coding rate and duration of vocalizations of the frog , Xenopus laevis | Vocalizations involve complex rhythmic motor patterns, but the underlying temporal coding mechanisms in the nervous system are poorly understood. Using a recently developed whole-brain preparation from which "fictive" vocalizations are readily elicited in vitro, we investigated the cellular basis of... | 2012-08-29 | |
| 6 |
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Bohs, Lynn A. | Solanaceae: the potato family | Shrubs, herbs, woody vines, occasionally trees, glabrous or pubescent with simple, glandular, branched, or star-shaped hairs, sometimes with prickles. Lvs alternate or paired but not truly opposite, simple or lobed to pinnately compound; stipules absent. Infl composed of variously modified terminal... | Browallia; Brugmansia; Brunfelsia; Capsicum; Cestrum; Petunia; Physalis; Solandra; Solanum; Streptosolen | 2005 |
| 7 |
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Ehleringer, James R. | Plant adaptation in the Great Basin and Colorado Plateau | Adaptive features of plants of the Great Basin are reviewed. The combination of cold winters and an arid to semiarid precipitation regime results in the distinguishing features of the vegetation in the Great Basin and Colorado Plateau. The primary effects of these climatic features arise from how t... | Plant adaptation; Great Basin; Colorado Plateau; Cold deserts | 1992 |
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