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Creator | Title | Description | Subject | Date |
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Calder, Dallen | Adipocyte enhancer binding protein 1 (AEBP1) as a potential therapeutic target to combat cardiac fibrosis | Fibrosis is one of the major hallmarks of heart failure (HF) progression and is characterized by fibroblast activation and excess extracellular matrix (EMC) deposition. RNA sequencing of myocardial tissue acquired from HF patients showed a significant upregulation of adipocyte enhancer binding prote... | | 2022 |
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Som, Sarita | Virus-like weapons used for competition in wild plant populations | Plant diseases caused by bacterial pathogens pose significant economic challenges globally, necessitating the exploration of alternative methods for controlling bacterial infections in plants. Tailocins, virus-like weapons produced by bacteria, have emerged as potent antibacterial agents and hold po... | | 2023 |
3 |
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Gardner, Jenna | The Disparity Between Student Science Writing and Professional Sciencetific Writing | There exists a disparity between student scientific writing and professional scientific writing. The audience, format, and intention of student papers as presented in the science classroom is different from those in the scientific field where the goal is to fully convince an unfamiliar audience and ... | | 2017 |
4 |
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Kim, Bum Jun | Does ceramide contribute to vascular dysfunction in mice with type 1 diabetes? | Approximately 2 million individuals have type 1 diabetes (T1D) in the United States. Cardiovascular disease is 2-4-fold more prevalent in these patients but the mechanism(s) is unclear. Recently, we showed that the sphingolipid ceramide contributes to arterial dysfunction and hypertension in mice wi... | Ceramide - Research; Type 1 Diabetes; Mice as laboratory animals | 2012-05 |
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Nguyen, Nam | Roles of Transient Receptor Potenitial Ankyrin-1 and Vanilloid-3 in Endoplasmic Reticulum stress and Cytotoxicity in Lung Epithelial Cells | Air pollution is a growing global health issue with considerable local relevance. In particular, exposure to wood smoke particulate matter (WSPM) is associated with the development and exacerbation of chronic inflammatory conditions and irreversible damage of the airways and alveoli. However, exact ... | | 2020 |
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Watson, Andre | Patterns of parasitism in a common Utah Rodent | Male-biased parasitism, where males are more commonly infected with and have higher parasite loads, is common across vertebrate taxa. Several factors could be driving this pattern. The immunocompetence handicap hypothesis suggests that higher testosterone levels in males suppress immune function whi... | | 2022 |
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Jensen, Madeline | Changes in microbial diversity in storm-water green infrastructure | Increased urbanization has led to excess nutrients in urban ecosystems. Stormwater Green Infrastructure (SGI) is a method to capture these nutrients and prevent runoff. However, an increased understanding of ecosystem processes is needed to create more efficient SGIs. Past studies have shown that pl... | | 2022 |
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| Effects of Acute Hypoxia and High pCO2 on Total Protein Content and Metabolic Enzyme Activity in Rockfishes (Sebastes SPP.) | Climate change is altering ocean chemistry and wind-driven upwelling regimes. In the California Current System (CCS), these changes are exposing nearshore fishes to increasing levels of high pCO2 and hypoxia. These stressors co-occur during upwelling events, lasting hours to days, and both have the ... | | 2019 |
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Roestenburg, Jessica | Testing the Perceptual Salience of Spectral Content in Zebra Finch Song | Birds actively adjust the resonance properties of the upper vocal tract during singing, which results in specific harmonic structures of song elements. To what degree upper vocal tract filtering is relevant for the perceptual salience of song is poorly understood. This research utilizes (1) a biolog... | | 2018 |
10 |
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Wheeler, Maya | Role of WNT-Dependent Neurogenesis in Functional Recovery Following Spinal Cord Injury | In humans and other adult mammals, spinal cord injury leads to a permanent loss of motor and sensory function. The biggest obstacle to recovery is the inability of severed axons and neurons to regenerate. During embryogenesis, all vertebrates have a population of neural stem cells called radial glia... | | 2019 |
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Kannan, Sarmishta Diraviam | The Role that Lysosomes and Autophagy play in Alveolar soft parts Sarcoma, clear cell Sarcoma and Synovial Sarcoma | Sarcomas are cancer of the connective tissue and are very deadly group of cancers. Two of the sarcoma types, alveolar soft parts sarcoma (ASPS) and clear cell sarcoma (CCS) have a unique vacuolar morphology. This unique morphology is absent in synovial sarcoma (SS). We believe that the unusual morph... | | 2017 |
12 |
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Sperber, Alexander M. | A novel approach to differentiating cardiac fibroblasts from induced pluripotent stem cells | Heart disease remains the leading cause of death in the United States, and such disease is caused by electrical, chemical, or biomechanical imbalances in the heart. The two most abundant cells comprising the heart that are responsible for these functions are cardiomyocytes and cardiac fibroblasts. I... | | 2022 |
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Woodruff, Derek | Uncovering Synaptic Defects resulting from loss of the intellectual disability and autism-associated gene Kirrel3 | Neurodevelopmental disorders severely impact an individual's life. Surprisingly, the genetic and cellular cause of over half of intellectual disability cases and more than 80% of autism spectrum disorders remain undiscovered1,2. It is likely that mutations in molecules regulating synapse development... | | 2017 |
14 |
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Tennant, Karrin | Competitive nighttime stomatal response of Populus Trichocarpa during drought | Stomata are critical valves responsible for gas exchange on the leaf level. They control rates of transpiration and as such play a crucial role in terrestrial water cycling. When stomata open, water molecules in the intracellular leaf space are subject to evaporation, especially in dry conditions. T... | | 2021 |
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Lan, Yung-Chi | HYPO-osmolarity and glucose starvation localizes slm1 to mitochondria- A novel stress response pathway | Synthetic Lethal with Mss4 1 (Slm1) is a key protein found in the crossroad of the Membrane Compartment of Can1 (MCC) and the Membrane Compartment of TORC2 (MCT). The two compartments on the plasma membrane of budding yeast (Saccharomyces cerevisiae) are responsible for APC transporter regulation an... | | 2022 |
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Richards, Jackson | Chasing channels: Progress in calcium channel localization in the C. Elegans synapse | Calcium channels play a crucial role in neurotransmission by facilitating the flow of calcium ions necessary for synaptic vesicle fusion and neurotransmitter release. Different types of calcium channels participate in this process in the neurons of the nematode C. elegans. L- and N-type channels res... | Calcium channels; Synaptic vesicles; Caenorhabditis elegans | 2013-05 |
17 |
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Davis, Kacey A. | Expression and Purification of Augertoxins: Searching for Novel Protein Folds in Venomous Marine Snails | This study describes a method for bacterial expression and purification of previously uncharacterized proteins. The proteins chosen for this study come from auger snail toxins, which have evolved to help the snail hunt and kill their prey. Evolutionary pressure between predator and prey selects for ... | | 2018 |
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Auduong, Priscilla | Spinal muscular atrophy modeled in drosophila melanogaster | Spinal Muscular Atrophy (SMA) is the most commonly inherited cause of death in children (Park, Kariya, & Monani, 2010 for review). This disease is characterized by a loss of motor neurons which leads to muscle degeneration, paralysis, and eventual death by respiratory failure (Monani, 2005 for revie... | Spinal muscular atrophy - Research; Drosophila melanogaster - Researcher | 2012-05 |
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Skedros, Gregory Athanasios | Structural and material changes in the sheep radius from newborn to adult: Functional adaptation versus developmental constraint | Bones that exhibit marked changes in structural and material characteristics during ontogeny are potentially useful for studying the mechanisms that produce functional adaptations. The diaphyseal region of the sheep radius was examined because it is relatively simply loaded in cranial-caudal bending... | Functional adaptations - Sheep; Developmental constraint - Sheep; Ontogeny | 2015-08 |