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CreatorTitleDescriptionSubjectDate
1 Hughes, Kelly T.ATPase-Independent Type-III Protein Secretion in Salmonella entericaType-III protein secretion systems are utilized by gram-negative pathogens to secrete building blocks of the bacterial flagellum, virulence effectors from the cytoplasm into host cells, and structural subunits of the needle complex. The flagellar type-III secretion apparatus utilizes both the energy...2014-01-01
2 Olivera, Baldomero M.?O-Conotoxins inhibit NaV channels by interfering with their voltage sensors in domain-2The ?O-conotoxins MrVIA and MrVIB are 31-residue peptides from Conus marmoreus, belonging to the O-superfamily of conotoxins with three disulfide bridges. They have attracted attention because they are inhibitors of tetrodotoxin-insensitive voltage-gated sodium channels (NaV1.8) and could therefore ...2007
3 Olivera, Baldomero M.Conus venom peptides, receptor and ion channel targets, and drug design: 50 million years of neuropharmacologyThe predatory cone snails (Conus) are among the most successful living marine animals (~500 living species). Each Conus species is a specialist in neuropharmacology, and uses venom to capture prey, to escape from and defend against predators and possibly to deter competitors. An individual cone...Conotoxins1997
4 Coley, Phyllis D.; Kursar, Thomas A.Effects of weather on fungal abundance and richness among 25 communities in the Intermountain WestBecause moisture and temperature influence the growth of fungi, characterizing weather conditions favorable for fungi may be used to predict the abundance and richness of fungi in habitats with different climate conditions. To estimate habitat favorability to fungi, we examined the relationship of f...Intermountain West; Utah; Microclimate; Fungal prevalence2002
5 Blair, David F.Electron spin relaxation of CuA and cytochrome a in cytochrome c oxidase: comparison to heme, copper, and sulfur radical complexesThe method of continuous saturation has been used to measure the electron spin relaxation parameter T1T2 at temperatures between 10 and 50 K for a variety of S = % species including: CuA and cytochrome a of cytochrome c oxidase, the type1 copper in several blue copper proteins, the type 2 coppe...Electron spin relaxation; EPR signals; Sulfur radical complexes1984
6 Olivera, Baldomero M.; McIntosh, J. Michaelα-Conotoxins ImI and ImII: similar α7 nicotinic receptor antagonists act at different sitesA novel conotoxin, α-conotoxin ImII (α-CTx ImII), identified from Conus imperialis venom ducts, was chemically synthesized. A previously characterized C. imperialis conotoxin, α-conotoxin ImI (α-CTx ImI), is closely related; 9 of 12 amino acids are identical. Both α-CTx ImII and α-CTx ImI...Conotoxins; Conotoxin ImI; Conotoxin ImII2003
7 Goller, FranzProsthetic Avian vocal organ controlled by a freely behaving bird based on a low dimensional model of the biomechanical peripheryBecause of the parallels found with human language production and acquisition, birdsong is an ideal animal model to study general mechanisms underlying complex, learned motor behavior. The rich and diverse vocalizations of songbirds emerge as a result of the interaction between a pattern generator i...2012-01-01
8 Hughes, Kelly T.FliT selectively enhances proteolysis of FlhC Subunit in FlhD4C2 complex by an ATP-dependent protease, ClpXPWe previously reported that the ClpXP ATP-dependent pro-tease specifically recognizes and degrades the flagellar master transcriptional activator complex, FlhD 4C2, to negatively control flagellar biogenesis. The flagellum-related protein, FliT, isalso a negative regulator of flagellar regulon by in...2014-01-01
9 Olivera, Baldomero M.Block of Shaker K+ channels by ĸ-conotoxin PVIIA is state dependentĸ-conotoxin PVIIA is the first conotoxin known to interact with voltage-gated potassium channels by inhibiting Shaker-mediated currents. We studied the mechanism of inhibition and concluded that PVIIA blocks the ion pore with a 1:1 stoichiometry and that binding to open or closed channels is very d...Conotoxins; k-conotoxin PVIIA; Potassium channel blockers; Shaker K+ channels1999
10 Adler, Frederick R.Long-term models of oxidative stress and mitochondrial damage in insulin resistance progressionInsulin resistance, characterized by a reduced cellular response to insulin, is a major factor in type 2 diabetes pathogenesis, with a complex etiology consisting of a combination of environmental and genetic factors. Oxidative stress, which develops through an accumulation of toxic reactive oxygen ...2014-01-01
11 Olivera, Baldomero M.Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snailsBackground: Conotoxins can be utilized to investigate enzyme-assisted folding of disulfide-rich peptides. Results: Various ER-resident cone snail enzymes act in concert to accelerate the oxidative folding of conotoxins and modulate their conformation by reconfiguring disulfide connectivities. Conclu...2012-01-01
12 Ehleringer, James R.; Negus, Norman C.Red Butte Canyon Research Natural Area: history, flora, geology, climate, and ecologyRed Butte Canyon is a protected, near pristine canyon entering Salt Lake Valley, Utah. It contains a well-developed riparian zone and a perennial stream; hillside vegetation ranges from grasslands on the lower limits to Douglas-fir and aspen stands at the upper elevations. In this paper we describe ...Intermountain West; Grassland; Oak-maple; Plant adaptation; Red Butte Canyon Research Natural Area; Human impact1992
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