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CreatorTitleDescriptionSubjectDate
126 Capecchi, Mario R.Purification and characterization of mouse hypoxanthine-guanine phosphoribosyltransferase.Hypoxanthine-guanine phosphoribosyltransferase (HGPR transferase) (EC 2.4.2.8) has been purified approximately 4500-fold to apparent homogeneity from mouse liver. The procedure involves the use of affinity chromatography and was designed to be readily adaptable to small scale isolations. The enzyme ...Buffers; Centrifugation, Density Gradient; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel1975-01-31
127 Sekercioglu, CaganThe effects of climate change on tropical birdsBirds are among the most widely studied organisms on earth and represent an important indicator group for learning about the effects of climate change - particularly in regard to the effects of climate change on tropical ecosystems. In this review, we assess the potential impacts of climate change o...2010-01-01
128 Beckerle, Mary C.; Hoffman, Laura M.Targeted disruption of the murine zyxin geneZyxin is an evolutionarily conserved protein that is concentrated at sites of cell adhesion, where it associates with members of the Enabled (Ena)/vasodilator-stimulated phosphoprotein (VASP) family of cytoskeletal regulators and is postulated to play a role in cytoskeletal dynamics and signaling.Zyxin2003
129 Farmer, Colleen G.; Carrier, David R.Integration of ventilation and locomotion in archosaursMovements of the pelvis have recently been found to contribute to ventilation in both crocodilians and birds. Alligators have a kinetic pelvis in which the ischiopubic and ischiotruncus muscles rotate the pubic bones ventrally to increase abdominal volume and thereby facilitate inspiration. In birds...Archosaurs; Theropods; Integration; Ventilation; Pelvic aspiration; Cuirassal breathing2000
130 Beckerle, Mary C.Purification and characterization of zyxin, an 82,000-Dalton component of adherens junctionsWe describe here the purification and characterization of a recently identified adherens junction protein that has an apparent molecular mass of 82 kDa on sodium dodecyl sulfate-polyacrylamide gels (Beckerle, M. C. (1986) J. Cell Biol. 103, 1679-1687). The 82-kDa protein was isolated from avian smoo...Zyxin1992
131 Clayton, Dale H.Reciprocal natural selection on host-parasite phenotypesCoevolution is evolution in one species in response to selection imposed by a second species, followed by evolution in the second species in response to reciprocal selection imposed by the first species. Although reciprocal selection is a prerequisite of coevolution, it has seldom been documented in...Host-parasite phenotypes; Ectoparasites; Virulence; Fitness1999
132 Hughes, Kelly T.The effect of cell growth phase on the regulatory cross-talk between flagellar and Spi1 virulence gene expressionThe flagellar regulon controls Salmonella biofilm formation, virulence gene expression and the production of the major surface antigen present on the cell surface: flagellin. At the top of a flagellar regulatory hierarchy is the master operon, flhDC, which encodes the FlhD4C2 transcriptional complex...2014-01-01
133 Ehleringer, James R.Fuentes de aqua utilizadas por las plantas desérticas y su importancia en planes de manejo y restauración ecológicaEl agua es el factor más importante que afecta a la productividad primaria y la estructura de la vegetación en ecosistemas áridos. Dado que las especies de plantas pueden diferir en sus capacidades de utilizar distintas fuentes de agua, el conocimiento de estos aspectos es fundamental para los ...Fuentes de agua; Isótopos estables; 8-H; 5 l sO; Zonas áridas; Plantas desérticas; Relaciones hídricas; Restauración ecológica; Desierto de Atacama; Atacama Desert; Stable isotopes; Water sources; Arid regions; Ecological restoration; Water relations; Water supplies2000
134 Beckerle, Mary C.LIM proteins in actin cytoskeleton mechanoresponseThe actin cytoskeleton assembles into branched networks or bundles to generate mechanical force for critical cellular processes such as establishment of polarity, adhesion, and migration. Stress fibers are contractile, actomyosin structures that physically couple to the extracellular matrix through ...2014-01-01
135 Adler, Frederick R.Long-term models of oxidative stress and mitochondrial damage in insulin resistance progressionInsulin resistance, characterized by a reduced cellular response to insulin, is a major factor in type 2 diabetes pathogenesis, with a complex etiology consisting of a combination of environmental and genetic factors. Oxidative stress, which develops through an accumulation of toxic reactive oxygen ...2014-01-01
136 Hultine, KevinEcohydrological implications of woody plant encroachmentIncreases in the abundance or density of woody plants in historically semiarid and arid grassland ecosystems have important ecological, hydrological, and socioeconomic implications. Using a simplified water-balance model, we propose a framework for conceptualizing how woody plant encroachment is li...Carbon cycling; ecohydrology; evapotranspiration2005
137 Capecchi, Mario R.Hoxb8 is required for normal grooming behavior in mice.Repertoires of grooming behaviors critical to survival are exhibited by most animal species, including humans. Genes that influence this complex behavior are unknown. We report that mice with disruptions of Hoxb8 show, with 100% penetrance, excessive grooming leading to hair removal and lesions. Add...Aging; Alleles; Animals, Newborn; Behavior, Animal; Bone and Bones; Disease Models, Animal; Mice, Knockout Nerve Net2002-01-03
138 Dale, Colin; Babst, MarkusQuorum sensing primes the oxidative stress response in the insect endosymbiont, Sodalis glossinidiusSodalis glossinidius, a maternally transmitted bacterial endosymbiont of tsetse flies (Glossina spp.), uses an acylated homoserine lactone (AHL)-based quorum sensing system to modulate gene expression in accordance with bacterial cell density. The S. glossinidius quorum sensing system relies on the...Endosymbionts; Sodalis glossinidius; Quorum sensing; Oxidative stress response2008
139 Sperry, John S.Shoot dieback during prolonged drought in Ceanothus (Rhamnaceae) chaparral of California: a possible case of hydraulic failureProgressive diebacks of outer canopy branchlets of Ceanothus crassifolius were repeatedly observed after rainless periods up to 9 mo in duration in the Santa Monica Mountains of southern California. Mean xylem pressures of branchlets near the end of drought were as low as -11.2 MPa (N = 22) with a m...Water relations; xylem cavitation; water-stress-induced loss2002
140 Capecchi, Mario R.Hematopoietic origin of pathological grooming in Hoxb8 mutant miceMouse Hoxb8 mutants show unexpected behavior manifested by compulsive grooming and hair removal similar to humans with OCD-spectrum disorder trichotillomania. Since Hox gene disruption often has pleiotropic effects, the root cause of this behavioral deficit was unclear. Here we report that, in the b...2010
141 Bastiani, MichaelCell-cell interactions during the migration of an identified commissural growth cone in the embryonic grasshopperOne of the fascicles of the posterior commissure of the embryonic grasshopper is pioneered by an individually identifiable neuron named Q1. Q1 initially grows along a longitudinal pathway established by another pioneer neuron, MPl, and then crosses to the midline, where it meets and fasciculates wi...Commissure; Pathfinding; Filopodia1993
142 Capecchi, Mario R.Patterns of integration of DNA microinjected into cultured mammalian cells: evidence for homologous recombination between injected plasmid DNA molecules.We examined the fate of DNA microinjected into nuclei of cultured mammalian cells. The sequence composition and the physical form of the vector carrying the selectable gene affected the efficiency of DNA-mediated transformation. Introduction of sequences near the simian virus 40 origin of DNA replic...Base Sequence; Cell Line; Genes, Viral; Genetic Vectors; Mice; Microinjections1982-11
143 Sperry, John S.Size and function in conifer tracheids and angiosperm vesselsThe wide size range of conifer tracheids and angiosperm vessels has important consequences for function. In both conduit types, bigger is better for conducting efficiency. The gain in efficiency with size is maximized by the control of conduit shape, which balances end-wall and lumen resistances.Ecological wood anatomy; vascular structure and function; water transport2006
144 Davidson, Diane W.Species diversity and community organization in desert seed-eating antsPatterns of species diversity and community organization in desert seed-eating ants were studied in 10 habitats on a longitudinal gradient of increasing rainfall extending from southeastern California, through southern Arizona, and into southwestern New Mexico. Local communities of harvester ants...Ants; Arizona; California; Communities; Competition; Desert Granivores; Diversity; Insects; New Mexico; Novomessor; Pheidole; Pogonomyrmex; Resource allocation; Veromessor.1977
145 Davidson, Diane W.Comparative structure of harvester ant communities in arid Australia and North AmericaIn the Australian arid zone, the species richness of ants is greater and that of mammalian granivores is less than in North American deserts. This study aimed to determine if the structure of harvester ant communities differs from that seen in North American deserts, focussing on differences relate...Species; Rodents; Diversity1988
146 Capecchi, Mario R.Hoxa1 lineage-tracing indicates a direct role for Hoxa1 in development of the inner ear, the heart and the third rhombomereLoss of Hoxa1 function results in severe defects of the brainstem, inner ear and cranial ganglia in humans and mice as well as cardiovascular abnormalities in humans. Since Hoxa1 is expressed very transiently during an early embryonic stage, it has been difficult to determine whether Hoxa1 plays a d...Hoxa1; Inner ear; Third rhombomere; Hindbrain; Hoxa1-IRES-Cre mouse; Embryonic development; Lineage-tracing2010
147 Coley, Phyllis D.Herbivory and defensive characteristics of tree species in a lowland tropical forestRate of herbivory and defensive characteristics of young and mature leaves were measured for saplings of 46 canopy tree species in a lowland tropical rain forest (Barro Colorado Island, Panama). Grazing rates were determined in the field for sample periods in the early wet, late wet, and dry seasons...Fiber; Herbivory; Life history; Panama; Phenolics; Plant growth; Spatial distribution; Tannins; Temporal distribution; Treefall gaps; Tropical forest1983
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