UScholar Works
 
Filters: Department: "Biology" School Or College: "College of Science" Collection: "ir_uspace"
51 - 75 of 147
Number of results to display per page
CreatorTitleDescriptionSubjectDate
51 Ehleringer, James R.Water and nitrogen uptake patterns following moisture pulses in a cold desert communityVariation in the ability to utilize pulses of both water and nitrogen (N) is one possible mechanism allowing the coexistence of species in the cold desert community on the Colorado Plateau. We simulated 25-mm precipitation events and used stable isotope tracers (2H and 15N) to follow water and N upt...Colorado Plateau; Desert perennials; Nitrogen uptake patterns; Pulse utilization; Resource partitioning; Stable isotopes; Water uptake patterns2000
52 Gesteland, Raymond F.; Atkins, John F.; Wills, Norma M.rRNA-mRNA base pairing stimulates a programmed -1 ribosomal frameshiftBase pairing between the 3' end of 16S rRNA and mRNA is shown to be important for the programmed -1 frameshifting utilized in decoding the Escherichia coli dnaX gene. This pairing is the same as the Shine-Dalgarno pairing used by prokaryotic ribosomes in selection of translation initiators, but for ...Frameshifting; Escherichia coli; Binding Sites; Base Composition1994
53 Olivera, Baldomero M.; Bandyopadhyay, Pradip K.Molecular phylogeny of some Indo-Pacific genera in the subfamily Turrinae H. Adams and A. Adams, 1853 (1838) (Gastropoda: Neogastropoda)We have carried out a phylogenetic analysis of a group of Indo-Pacific species in the subfamily Turrinae (Swainson, 1840) using 128 mitoehondrial ribosomal RNA gene sequcnces Most of the species analyzed are convenlionally assigned to one of there Lophiotoma Casey, 1904. The inolecular anaysis revea...Turrinae; Indo-Pacific; Mitochondrial RNA; Molecular phylogeny2007
54 Jorgensen, ErikTrio's Rho-specific GEF domain is the missing Gaq effector in C. elegansThe Gaq pathway is essential for animal life and is a central pathway for driving locomotion, egg laying, and growth in Caenorhcibditis elegans, where it exerts its effects through EGL-8 (phospholipase CB [PLCB]) and at least one other effector. To find the missing effector, we performed forward ...2007-11-01
55 Jorgensen, ErikUNC-11, a Caenorhabditis elegans AP180 homologue, regulates the size and protein composition of synaptic vesiclesThe unc-11 gene of Caenorhabditis elegans encodes multiple isoforms of a protein homologous to the mammalian brain-specific clathrin-adaptor protein AP180. The UNC-11 protein is expressed at high levels in the nervous system and at lower levels in other tissues. In neurons, UNC-11 is enriched at pr...Caenorhabditis elegans; Synaptic vesicles; unc-11; Synaptobrevin; Endocytosis1999
56 Capecchi, Mario R.Illegitimate cre-dependent chromosome rearrangements in transgenic mouse spermatids.The bacteriophage P1 Cre/loxP system has become a powerful tool for in vivo manipulation of the genomes of transgenic mice. Although in vitro studies have shown that Cre can catalyze recombination between cryptic "pseudo-loxP" sites in mammalian genomes, to date there have been no reports of loxP-si...Chromatin; Female; Mice, Inbred C57BL; Phenotype2000-12-05
57 Olivera, Baldomero M.Poly(ADP-ribosylation) of DNA topoisomerase I: a nuclear response to DNA-strand interruptionsDNA in eukaryotic chromosomes is organized differently from prokaryotic DNA. It seems highly probable that mechanistic adjustments have been made in macromolecular DNA metabolism as a consequence of the chromatin structure of the eukaryotic chromosome (Igo-Kemenes et al. 1982)). This paper deals ...Poly(ADP-ribosylation); Poly(ADP-ribose) synthetase; DNA strand interruption1984
58 Adler, Frederick R.Departure time versus departure rate: how to forage optimally when you are stupidForagers unable to leave a patch at the optimal moment must act as constrained foragers. Extending the results of Houston and McNamara (1985), we compare a blundering forager that leaves patches at a constant rate with an unconstrained optimal forager that leaves patches at the optimal time.Blundering Foragers; Foraging; Marginal Value Theorem1999
59 Beckerle, Mary C.; Clark, Kathleen A.Conserved LIM protein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegansWe describe here the molecular and functional characterization of the Caenorhabditis elegans unc-97 gene, whose gene product constitutes a novel component of muscular adherens junctions. UNC-97 and homologues from several other species define the PINCH family, a family of LIM proteins whose modula...LIM domains; Caenorhabditis elegans; UNC-97; Adherens junction; Touch neuron; Muscle development1999
60 Olivera, Baldomero M.Novel Conus peptide ligand for K+ channelsVoltage-gated ion channels determine the membrane excitability of cells. Although many Conus peptides that interact with voltage-gated Na+ and Ca2+ channels have been characterized, relatively few have been identified that interact with K+ channels. We describe a novel Conus peptide that intera...Conus peptides; Conotoxins2003
61 Capecchi, Mario R.Housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland.Xanthine oxidoreductase (XOR) is the rate-limiting enzyme in purine catabolism occurring in most cell types. However, this housekeeping gene is expressed at very high levels in a number of mammalian tissues including the lactating mammary epithelium, suggesting additional roles for XOR in these tiss...Body Weight; Cell Differentiation; Cell Membrane; Epithelium2002-12-15
62 Jorgensen, ErikNeural plasticityNeural plasticity refers to functional changes in the nervous system and therefore encompasses a range of phenomena from changes at synapses observed on a microscopic scale to changes in behavior observed in the whole animal. These diverse phenomena are related since changes in synapses are believ...Synapses; Nervous System; Development1997
63 Jorgensen, ErikGenetic screens for synaptic function mutants in the nematode C. elegansThe synapse is the site of a remarkable conversion of electrical signals into chemical signals. This conversion takes place when a depolarizing impulse enters the axon terminal and opens voltage-sensitive calcium channels; calcium then flows into the cell and initiates the fusion of synaptic vesicle...Vesicle; Neurotransmission; Cell1996
64 Capecchi, Mario R.Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy.Although the role of Hox genes in patterning the mammalian body plan has been studied extensively during embryonic and fetal development, relatively little is known concerning Hox gene function in adult animals. Analysis of mice with mutant Hoxa9, Hoxb9, and Hoxd9 genes shows that these paralogous g...Embryonic and Fetal Development; Gene Expression Regulation, Developmental; Genotype; Mice, Knockout1999-01
65 Capecchi, Mario R.Selective degradation of abnormal proteins in mammalian tissue culture cells.The degradation rates of several missense mutants of hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) in mouse L cells are compared to those of the wild-type enzyme. Although the rates of total protein breakdown in the mutant cell lines are identical to that of the parental L cell line, ...Gene Expression Regulation; Mice, Transgenic; Microscopy, Fluorescence1974-12-01
66 Coley, Phyllis D.; Kursar, Thomas A.Effects of weather on fungal abundance and richness among 25 communities in the Intermountain WestBecause moisture and temperature influence the growth of fungi, characterizing weather conditions favorable for fungi may be used to predict the abundance and richness of fungi in habitats with different climate conditions. To estimate habitat favorability to fungi, we examined the relationship of f...Intermountain West; Utah; Microclimate; Fungal prevalence2002
67 Coley, Phyllis D.; Kursar, Thomas A.Using ecological criteria to design plant collection strategies for drug discoveryTropical forests are one of the most diverse and endangered habitats on earth. They have also been portrayed as a source of future pharmaceuticals, yet finding useful compounds can be both scientifically and politically challenging. Increasingly, over the past decade, the potential value of medicina...Drug discovery; Biodiversity2003
68 Hultine, Kevin; Bush, Sarah Elizabeth; Ehleringer, James R.Effect of gender on sap-flux-scaled transpiration in a dominant riparian tree species: Box elder (Acer negundo)Acer negundo is a dioecious riparian tree species with a spatial segregation of the sexes along soil moisture gradients. Females are typically more common in wet sites along streams (typically F/M = 1.6), whereas males are more common in drier sites away from streams (typically F/M = 0.6). Spatial s...Density; Ecosystem; Segregation2007
69 Capecchi, Mario R.Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation.hoxb-5 and hoxb-6 are adjacent genes in the mouse HoxB locus and are members of the homeotic transcription factor complex that governs establishment of the mammalian body plan. To determine the roles of these genes during development, we generated mice with a targeted disruption in each gene. Three ...Alleles; CCAAT-Enhancer-Binding Proteins; Cervical Vertebrae; DNA-Binding Proteins; Forelimb; Genetic Complementation Test1995-01-01
70 Ehleringer, James R.; Belnap, JayneSensitivity of the Colorado plateau to change: climate, ecosystems, and societyThe Colorado Plateau is located in the interior, dry end of two moisture trajectories coming from opposite directions, which have made this region a target for unusual climate fluctuations. A multidecadal drought event some 850 years ago may have eliminated maize cultivation by the first human settl...Colorado Plateau; Biological crust; Climate change; Megadrought; Ranching; Dry crop productivity; Extractive industries; Pueblo Indians; Fremont culture2008
71 Capecchi, Mario R.Hox11 paralogous genes are essential for metanephric kidney inductionThe mammalian Hox complex is divided into four linkage groups containing 13 sets of paralogous genes. These paralogous genes have retained functional redundancy during evolution. For this reason, loss of only one or two Hox genes within a paralogous group often results in incompletely penetrant phen...Metanephric; Six2; Wt12002-06-01
72 Jorgensen, ErikCaenorhabditis elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesiclesRab molecules regulate vesicular trafficking in many different exocytic and endocytic transport pathways in eukaryotic cells. In neurons, rab3 has been proposed to play a crucial role in regulating synaptic vesicle release. To elucidate the role of rab3 in synaptic transmission, we isolated and cha...1997
73 Gesteland, Raymond F.; Atkins, John F.Frameshifting in gene 10 of bacteriophage T7Gene 10 of bacteriophage T7, which encodes the most abundant capsid protein, has two products: a major product, 10A (36 kDa), and a minor product, 10B (41 kDa). 10B is produced by frameshifting into the -1 frame near the end of the 10A coding frame and is incorporated into the capsid. The frameshift...Frameshifting; Bacteriophage T7; RNA, Viral; Gene Expression1991
74 Jorgensen, ErikCaenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptorIonotropic GABA receptors generally require the products of three subunit genes. By contrast, the GABA receptor needed for locomotion in Caenorhabditis elegans requires only the unc-49 gene. We cloned unc-49 and demonstrated that it possesses an unusual overlapping gene structure.1999
75 Capecchi, Mario R.Generating mice with targeted mutations.Mutational analysis is one of the most informative approaches available for the study of complex biological processes. It has been particularly successful in the analysis of the biology of bacteria, yeast, the nematode worm Caenorhabditis elegans and the fruit fly Drosophila melanogaster. Extension ...Animals; Recombination, Genetic; Stem Cells2001-10-01
51 - 75 of 147