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1 Cieri, RobertNew insight into the evolution of the vertebrate respiratory system and the discovery of unidirectional airflow in iguana lungsThe generally accepted framework for the evolution of a key feature of the avian respiratory system, unidirectional airflow, is that it is an adaptation for efficiency of gas exchange and expanded aerobic capacities, and therefore it has historically been viewed as important to the ability of birds ...2014-11-17
2 Bohs, Lynn A.Phylogeny of the carolinense clade of solanum (Solanaceae) inferred from nuclear and plastid DNA sequencesThe large and economically important genus Solanum contains ca. 1,400 species distributed worldwide. One of the 12-14 major clades identified in the genus is the Leptostemonum clade, or the "spiny solanums." Previous molecular phylogenetic studies have identified 14 major clades in the spiny solanum...2014-01-01
3 Adler, Frederick R.Reply:We appreciate the comments of Drs. Craig and Simpson and Drs. Mullins and Schwartz, and the challenge they raise to make MALD more believable, comprehensible, and usable. Acetaminophen (APAP) toxicity is indeed a complex process involving multiple steps. Although the underlying mathematics is more i...2012-01-01
4 Capecchi, Mario R.Modeling alveolar soft part sarcomagenesis in the mouse: a role for lactate in the tumor microenvironmentAlveolar soft part sarcoma (ASPS), a deadly soft tissue malignancy with a predilection for adolescents and young adults, associates consistently with t(X;17) translocations that generate the fusion gene ASPSCR1-TFE3. We proved the oncogenic capacity of this fusion gene by driving sarcomagenesis in m...2014-01-01
5 Olivera, Baldomero M.Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snailsBackground: Conotoxins can be utilized to investigate enzyme-assisted folding of disulfide-rich peptides. Results: Various ER-resident cone snail enzymes act in concert to accelerate the oxidative folding of conotoxins and modulate their conformation by reconfiguring disulfide connectivities. Conclu...2012-01-01
6 Parkinson, John StansfieldMutational analysis of the P1 phosphorylation domain in E. coli CheA, the signaling kinase for chemotaxisThe histidine autokinase CheA functions as the central processing unit in the Escherichia coli chemotaxis signaling machinery. CheA receives autophosphorylation control inputs from chemoreceptors and in turn regulates the flux of signaling phosphates to the CheY and CheB response regulator proteins...2014-01-01
7 Jorgensen, ErikNano-fEM: Protein localization using photo-activated localization microscopy and electron microscopyMapping the distribution of proteins is essential for understanding the function of proteins in a cell. Fluorescence microscopy is extensively used for protein localization, but subcellular context is often absent in fluorescence images. Immuno-electron microscopy, on the other hand, can localize pr...2012-01-01
8 Capecchi, Mario R.Sepp1UF forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1Mouse selenoprotein P (Sepp1) consists of an N-terminal domain (residues 1-239) that contains 1 selenocysteine (U) as residue 40 in a proposed redox-active motif (-UYLC-) and a Cterminal domain (residues 240-361) that contains 9 selenocysteines. Sepp1 transports selenium from the liver to other tiss...2014-01-01
9 Farmer, Colleen G.Unidirectional pulmonary airflow patterns in the savannah monitor lizardThe unidirectional airflow patterns in the lungs of birds have long been considered a unique and specialized trait associated with the oxygen demands of flying, their endothermic metabolism1 and unusual pulmonary architecture2,3. However, the discovery of similar flow patterns in the lungs of crocod...2014-02-20
10 Bohs, Lynn A.Two new species from the brevantherum clade of solanum (solanaceae) from eastern BrazilTwo new species of Solanum (Solanaceae) from eastern Brazil are described. Solanum anisocladum Giacomin & Stehmann is similar to S. megalochiton Mart., but differs by the indument of the adaxial leaf surface, which is composed of long porrect-stellate and unbranched trichomes. It also has a more rob...2013-01-01
11 Jorgensen, ErikUNC-41/stonin functions with AP2 to recycle synaptic vesicles in Caenorhabditis elegansThe recycling of synaptic vesicles requires the recovery of vesicle proteins and membrane. Members of the stonin protein family (Drosophila Stoned B, mammalian stonin 2) have been shown to link the synaptic vesicle protein synaptotagmin to the endocytic machinery. Here we characterize the unc-41 gen...2012-01-01
12 Jorgensen, ErikInterferometric localization microscopyInterference of signal in Fourier space, emitted from single probes, is used to localize it by recording and computing the phase of the fringes. Such system has applications in super resolution localization microscopy.2014-01-01
13 Sekercioglu, CaganMapping functional traits: comparing bundance and presence-absence estimates at large spatial scalesEfforts to quantify the composition of biological communities increasingly focus on functional traits. The composition of communities in terms of traits can be summarized in several ways. Ecologists are beginning to map the geographic distribution of trait-based metrics from various sources of data,...2012-01-01
14 Beckerle, Mary C.Mathematical modeling of the dynamic mechanical behavior of neighboring sarcomeres in actin stress fibersActin stress fibers (SFs) in live cells consist of series of dynamic individual sarcomeric units. Within a group of consecutive SF sarcomeres, individual sarcomeres can spontaneously shorten or lengthen without changing the overall length of this group, but the underlying mechanism is unclear. We us...2014-01-01
15 Adler, Frederick R.Mathematical modeling of liver injury and dysfunction after acetaminophen overdose: early discrimination between survival and deathAcetaminophen is the leading cause of acute liver injury in the developed world. Timely administration of N-Acetylcysteine (N-Ac) prevents the progression of serious liver injury and disease, while failure to administer N-Ac within a critical time frame allows disease progression and in the most sev...2012-01-01
16 Hughes, Kelly T.The effects of codon context on in vivo translation speedWe developed a bacterial genetic system based on translation of the his operon leader peptide gene to determine the relative speed at which the ribosome reads single or multiple codons in vivo. Low frequency effects of so-called ‘‘silent'' codon changes and codon neighbor (context) effects could...2014-01-01
17 Parkinson, John StansfieldHAMP domain structural determinants for signalling and sensory adaptation in Tsr, the E. coli serine chemoreceptorMotile Escherichia coli cells track chemical gradients with high sensitivity over wide concentration ranges [recently reviewed in (Hazelbauer et al., 2008; Hazelbauer & Lai, 2010)]. Stimulus detection, amplification, and integration occur in an arrayed network of signaling complexes that contain tra...2014-01-01
18 Clayton, Dale H.How effective is preening against mobile ectoparasites? An experimental test with pigeons and hippoboscid fliesBirds combat ectoparasites with many defences but the first line of defence is grooming behaviour, which includes preening with the bill and scratching with the feet. Preening has been shown to be very effective against ectoparasites. However, most tests have been with feather lice, which are relati...2012-01-01
19 Sekercioglu, CaganIbis questThe day I arrived in Ethiopia, researcher Yilma Dellelegn Abebe of the Ethiopia Wildlife and Natural History Society (EWNHS) was just leaving the capital city, Addis Ababa, to search for three Northern Bald Ibises in a remote, roadless area of the country. These critically endangered birds had been ...2007-01-01
20 Sekercioglu, CaganKeystone species in seed dispersal networks are mainly determined by dietary specializationOne central issue in Ecology ecology has been the definition and identification of keystone species, i.e., species that are relatively more important than others for maintaining the structure of a community. Several keystone species concepts have been proposed, and network theory has been pointed o...2014-01-01
21 Sekercioglu, CaganLandscape constraints on functional diversity of birds and insects in tropical agroecosystemsIn this paper, we analyze databases on bird and insects to assess patterns of functional diversity in human-dominated landscapes in the tropics. Perspective from developed landscapes is essential for understanding remnant natural ecosystems, because most species experience their surroundings at spat...2008-01-01
22 Hughes, Kelly T.FliT selectively enhances proteolysis of FlhC Subunit in FlhD4C2 complex by an ATP-dependent protease, ClpXPWe previously reported that the ClpXP ATP-dependent pro-tease specifically recognizes and degrades the flagellar master transcriptional activator complex, FlhD 4C2, to negatively control flagellar biogenesis. The flagellum-related protein, FliT, isalso a negative regulator of flagellar regulon by in...2014-01-01
23 Sekercioglu, CaganForest fragmentation hits insectivorous birds hardHabitats around the world, especially in the tropics, are being fragmented at a rapid rate, causing a tremendous loss of biodiversity[1]. For example, 12% of the approximately 10,000 bird species are threatened with extinction in the next 10 to 100 years, and another 8% are near-threatened[2]. This ...2002-01-01
24 Bowling, David R.Impacts of anthropogenic emissions and cold air pools on urban to montane gradients of snowpack ion concentrations in the Wasatch Mountains, UtahUrban montane valleys are often characterized by periodic wintertime temperature inversions (cold air pools) that increase atmospheric particulate matter concentrations, potentially stimulating the deposition of major ions to these snow-covered ecosystems. We assessed spatial and temporal patterns o...2014-01-01
25 Sekercioglu, CaganImpacts of birdwatching on human and avian communitiesEcotourism can be a vehicle for community-based conservation if it is conducted with an emphasis on the well-being of local ecosystems and human communities. Birdwatchers form the largest group of ecotourists, and are, on average, well-educated, wealthy and committed. This makes them ideal ecotouris...2002-01-01
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