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Creator | Title | Description | Subject | Date |
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Dart, Emily | Diversity and metabolic potential of microbial communities in a site of continental serpentinization | The geochemical process of serpentinization releases energy and organic carbon: two of the basic requirements need ed to support life. Sites of active serpentinization in the deep subsurface provide the intriguing possibility of a non-photosynthetically -supported biosphere. However, serpentinizatio... | Microbial ecology - Research; Serpentine - Environmental aspects; Gros Morne National Park (N.L.); Syntrophomonadaceae; Serpentinizaiton; Tabeland Ophiolite | 2016-05 |
2 |
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Shimko, Tyler | Mapping suppressors of premature sperm activation in C. Elegans | The sperm of the roundworm Caenorhabditis elegans move by a crawling motion, in contrast to mammalian sperm, which exhibit a swimming motion. This method of locomotion makes the sperm of C. elegans an excellent model for examining cell motility. In order to become motile, the sperm must undergo the ... | Caenorhabditis elegans -- Spermatozoa; Sperm activation | 2015-05 |
3 |
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| Effects of Acute Hypoxia and High pCO2 on Total Protein Content and Metabolic Enzyme Activity in Rockfishes (Sebastes SPP.) | Climate change is altering ocean chemistry and wind-driven upwelling regimes. In the California Current System (CCS), these changes are exposing nearshore fishes to increasing levels of high pCO2 and hypoxia. These stressors co-occur during upwelling events, lasting hours to days, and both have the ... | | 2019 |
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Richards, Jackson | Chasing channels: Progress in calcium channel localization in the C. Elegans synapse | Calcium channels play a crucial role in neurotransmission by facilitating the flow of calcium ions necessary for synaptic vesicle fusion and neurotransmitter release. Different types of calcium channels participate in this process in the neurons of the nematode C. elegans. L- and N-type channels res... | Calcium channels; Synaptic vesicles; Caenorhabditis elegans | 2013-05 |
5 |
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Loret, Amy | Genetic Modifiers of Severity in Collagen VI-Related Muscular Dystrophy | Collagen VI-related muscular dystrophies (COL6-RD) display phenotypic heterogeneity that includes mild Bethlem myopathy (BM), intermediate (INT), and severe Ullrich congenital muscular dystrophy (UCMD) phenotypes. COL6-RD are characterized by mutations within the collagen VI genes (COL6A1, COL6A2, a... | | 2019 |
6 |
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Fackler, Anderson N. | Identification of Kin-20 and UNC-119 Knockout suppressors associated with neuronal development and maintenance in C. elegans | Neurons comprise the nervous system-the essential signaling and communication system for nearly all multicellular organisms. To coordinate cells across an entire organism, they must grow to be relatively long. Therefore, neurons extend axons from the cell body. Immature neurons extend growth cones a... | | 2018 |
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Barbeau, William | Characterization of a New Ribosome Associated Quality Control Pathway | Proteins are life's double edged sword. Proteins are essential macromolecules of life, and the tasks that some proteins accomplish are quite marvelous. At the same time, if proteins misfold they have the potential to kill the cell that harbors them. It is becoming increasingly clear that proteins ha... | Ribosomes - Research | 2016-12 |
8 |
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Auduong, Priscilla | Spinal muscular atrophy modeled in drosophila melanogaster | Spinal Muscular Atrophy (SMA) is the most commonly inherited cause of death in children (Park, Kariya, & Monani, 2010 for review). This disease is characterized by a loss of motor neurons which leads to muscle degeneration, paralysis, and eventual death by respiratory failure (Monani, 2005 for revie... | Spinal muscular atrophy - Research; Drosophila melanogaster - Researcher | 2012-05 |
9 |
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Estrada, Johanna | BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Philadelphia cromosome-positive leukemia | CML 1s caused by a random reciprocal translocation that joins the ABL1 gene on chromosome 9, with the BCR gene on chromosome 22. The result is the formation of the oncogenic BCR-ABL1 gene. This derivative chromosome is widely known as the Philadelphia Chromosome (Ph+), and it encodes a deregulated, ... | Leukemia -- Genetic aspects -- Research Leukemia -- Treatment -- Research | 2014-04 |
10 |
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Prestgard-Duke, Michael | Dynamin localization in Caenorhabditis Elegans | Dynamin is a 100-KDa GTPase that is essential for endocytosis. The classic model of endocytosis is a sequential mechanism: first, cell membrane is bent and internalized via the formation of a clathrin coat; next, dynamin facilitates GTP hydrolysis, resulting in membrane scission as the newly formed ... | Caenorhabditis elegans; Guanosine triphosphatase; Endocytosis | 2014-05 |
11 |
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Tazehabadi, Tara | Bioinformatics to detect functional interactions important for the DNA repair enzyme mutyh | DNA is the blueprint of all biological life as it provides the means necessary for sharing of genetic information. DNA is formed and stabilized by interactions between four unique bases, Adenine (A), Cytosine (C), Guanine (G), and Thymine (T) which come together in predetermined patterns to create a... | | 2022 |
12 |
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Guernsey, Michael | Mclr is not solely responsible for pigmentation variation among domestic pigeons | Feather pigmentation in the domesticated rock pigeon, Columba livia, is stunningly diverse. Plumage pigmentation in this, and other, columbid (pigeon and dove) species plays an important role in mate choice and thus is a driving factor in the process of sexual selection. To study the genetic basis o... | | 2012 |