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Filters: Department: "Biology" Date: "2010" Collection: ir_uspace
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CreatorTitleDescriptionSubjectDate
1 Adler, Frederick R.Alternating host cell tropism shapes the persistence, evolution and coexistence of Epstein-Barr virus infections in humanEpstein-Barr virus (EBV) infects and can persist in a majority of people worldwide. Within an infected host, EBV targets two major cell types, B cells and epithelial cells, and viruses emerging from one cell type preferentially infect the other. We use mathematical models to understand why EBV infec...2010
2 Olivera, Baldomero M.Biochemical characterization of ?M-RIIIJ, a Kv1.2 channel blocker: evaluation of cardioprotective effects of ?M-conotoxinsConus snail (Conus) venoms are a valuable source of pharmacologically active compounds; some of the peptide toxin families from the snail venoms are known to interact with potassium channels. We report the purification, synthesis, and characterization of ?M-conotoxin RIIIJ from the venom of a fish-...2010
3 Olivera, Baldomero M.Defining a clade by morphological, molecular, and toxinological criteria: distinctive forms related to Conus praecellens A. Adams, 1854 (Gastropoda: Conidae)We carried out a definition of the Conus praecellens A. Adams, 1854, species group using a combination of comparative morphological data, molecular phylogeny based on standard genetic markers, and toxinological markers. Prior to this work, Conus praecellens was generally postulated to belong to a cl...Turriconus; 12SrRNA sequences; Phylogenetic analysis; Conus praecellens; Exogenes2010
4 Shapiro, Michael D.Divergence, convergence, and the ancestry of feral populations in the domestic rock pigeonDomestic pigeons are spectacularly diverse and exhibit variation in more traits than any other bird species [1]. In The Origin of Species, Charles Darwin repeatedly calls attention to the striking variation among domestic pigeon breeds - generated by thousands of years of artificial selection on a s...2010
5 Ehleringer, James R.; Bush, Sarah ElizabethEcophysiology of riparian cottonwood and willow before, during, and after two years of soil water removalRiparian cottonwood/willow forest assemblages are highly valued in the southwestern United States for their wildlife habitat, biodiversity, and watershed protection. Yet these forests are under considerable threat from climate change impacts on water resources and land-use activities to support hum...Riparian cottonwood; Riparian willow; Soil water removal; Coyote willow; Drought recovery; Populus fremontii; Riparian ecology; Red Butte Canyon Research Natural Area; Salix exigua; Stem sap flux; Leaf carbon isotope ratios2010
6 Adler, Frederick R.Effects of intraspecific density-dependence on species richness and species abundance distributionsAbstract Species richness and patterns of abundance result from the interplay between niche differences, realized as intraspecific density-dependence (IDD), and so-called neutral processes that arise when species fitnesses are similar. This paper presents an extension of neutral models that incorpo...2010
7 Bohs, Lynn A.Eggplant origins: out of Africa, into the OrientThe eggplant (Solanum melongena L.), also known as aubergine or brinjal, has been cultivated for centuries in the Old World and is currently a crop species of global importance. Despite this, hypotheses of eggplant evolution have been fraught with controversy. Previous conclusions have relied solely...Eggplant origins; Crop domestication; Solanum melongena complex; Solanum incanum; DNA sequence; Africa; Asia2010
8 Capecchi, Mario R.Hematopoietic origin of pathological grooming in Hoxb8 mutant miceMouse Hoxb8 mutants show unexpected behavior manifested by compulsive grooming and hair removal similar to humans with OCD-spectrum disorder trichotillomania. Since Hox gene disruption often has pleiotropic effects, the root cause of this behavioral deficit was unclear. Here we report that, in the b...2010
9 Capecchi, Mario R.Hoxa1 lineage-tracing indicates a direct role for Hoxa1 in development of the inner ear, the heart and the third rhombomereLoss of Hoxa1 function results in severe defects of the brainstem, inner ear and cranial ganglia in humans and mice as well as cardiovascular abnormalities in humans. Since Hoxa1 is expressed very transiently during an early embryonic stage, it has been difficult to determine whether Hoxa1 plays a d...Hoxa1; Inner ear; Third rhombomere; Hindbrain; Hoxa1-IRES-Cre mouse; Embryonic development; Lineage-tracing2010
10 Olivera, Baldomero M.Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxinsPeptidylprolyl cis-trans isomerases (PPIases) are ubiquitous proteins that catalyze the cis-trans isomerization of prolines. A number of proteins, such as Drosophila rhodopsin and the human immunodeficiency viral protein HIV-1 Gag, have been identified as endogenous substrates for PPIases. However, ...2010
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