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Creator | Title | Description | Subject | Date |
| 1 |
 | Lam, LeAnn | Pre-clinical animal model for ovarian cancer using live imaging system | Development of a live imaging animal model for orthotopic ovarian cancers in order to better understand disease mechanisms and response to potential anticancer drug treatments. | Ovarian cancer; Cancer; Animal model; Live imaging; Cell culture; ACCESS | 2015-04-14 |
| 2 |
 | Macleod, Robert S. | Sensitivity and specificity of substrate mapping: An in silico framework for the evaluation of electroanatomical substrate mapping strategies | Background - Voltage mapping is an important tool for characterizing proarrhythmic electrophysiological substrate, yet it is subject to geometric factors that influence bipolar amplitudes and thus compromise performance. The aim of this study was to characterize the impact of catheter orientation on... | | 2014-01-01 |
| 3 |
 | Vardhan, Avantika | Characterizing growth patterns in longitudinal MRI using image contrast | Understanding the growth patterns of the early brain is crucial to the study of neuro-development. In the early stages of brain growth, a rapid sequence of biophysical and chemical processes take place. A crucial component of these processes, known as myelination, consists of the formation of a myel... | | 2014-01-01 |
| 4 |
 | Gerig, Guido | Neuro imaging research lab | | | 2012 |
| 5 |
 | Christensen, Douglas A. | Ultrasound beam simulations in inhomogeneous tissue geometries using the hybrid angular spectrum method | The angular spectrum method is a fast, accurate and computationally efficient method for modeling wave propagation. However, the traditional angular spectrum method assumes that the region of propagation has homogenous properties. In this paper, the angular spectrum method is extended to calculate u... | | 2012-01-01 |
| 6 |
 | Jenson, Justin Michael; Bock, Susan C. | Mitigating spinal cord injury | How would your life change if you became one of the 15,000 Americans to suffer a spinal cord injury this year? Trauma to the spinal cord causes immediate loss of function below the level of the injury. Then, in the hours and days after the accident, the body's secondary injury response may extend ... | Trapeze Interactive Poster | 2010-03-15 |
| 7 |
 | Collins, Zachary J.; Poelzing, Steven | Characterization of a four-camera ratiometric optical mapping system | Electrical activity precedes calcium mediated heart contractions. Optical mapping takes advantage of minimally invasive fluorescent molecular probes to image both electrical and calcium activity. These molecular probes allow for ratiometric imaging. We characterize a four camera system capable of... | Optical mapping; Ratiometric imaging; Di-4-ANEPPS; Indo-1; Trapeze Interactive Poster | 2010-03-15 |
| 8 |
 | Angelucci, Alessandra; Lund, Jennifer S. | Circuits for local and global signal integration in primary visual cortex | Contrast-dependent changes in spatial summation and contextual modulation of primary visual cortex (V1) neuron responses to stimulation of their receptive field reveal long-distance integration of visual signals within V1, well beyond the classical receptive field (cRF) of single neurons. To identif... | Primary Visual Cortex; Extrastriate Cortex; Feed-back Connections; Lateral Connections; SUrround Modulation; Macaque | 2002-10-01 |
| 9 |
 | Horch, Kenneth W. | Acoustic interneurons of fiddler and ghost crabs | The properties of acoustic interneurons in fiddler (Uca pugilalor and U. minax) and ghost (Ocvpade qucldrula) crabs are described, as revealed bv tests with pure tones. Three types of interneurons were present in all species: tonic, which fired for the duration of the stimulus; phasic, which fire... | Acoustic crabs; Neural recording; Vibration reception | 1976 |
| 10 |
 | Horch, Kenneth W. | Selective activation of muscle groups in the feline hindlimb thorough electrical microstimulation of the ventral lumbo-sacral spinal cord | Selective activation of muscle groups in the feline hindlimb by electrical stimulation of the ventral lumbo-sacral spinal cord was investigated. Spinal cord segments L5 to S1 were mapped using a penetrating tungsten needle electrode. Locations that produced isolated contraction of quadriceps, ti... | Functional electrical stimulation; Motor pools; Spinal chord stimulation | 2000 |
| 11 |
 | Christensen, Douglas A.; Herron, James N. | Rapid clinical diagnostics assays using injection-molded planar waveguides | The goal of our research program is to develop an evanescent wave immunoassay system that can be used in point-of-care and critical care settings. Several key attributes are required to accomplish this goal: (i) the assay system should be at least as sensitive as present day immunoassays; (ii) assay... | Planar waveguides; Creatine phosphokinase MB (CK-MB); Cardiac troponin I (cTnl); Diagnostics; Evanescence; Fluorescence; Human chorionic gonadotropin (hCG) | 1998 |
| 12 |
 | Normann, Richard A.; Campbell, Patrick K.; Jones, Kelly E.; Huber, Robert J.; Horch, Kenneth W. | Silicon-based, three-dimensional neural interface: manufacturing processes for an intracortical electrode array | A method has been developed for the manufacture of a "three-dimensional" electrode array geometry for chronic intracortical stimulation. This silicon based array consists of a 4.2 x 4.2 x 0.12 mm thick monocrystalline substrate, from which project 100 conductive, silicon needles sharpened to facilit... | Electric Stimulation; Electrodes, Implanted; Sensory Cortex; Intracortical Electrode Array | 1991 |
| 13 |
 | Horch, Kenneth W. | On the number and nature of regenerating myelinated axons after lesions of cutaneous nerves in the cat | 1. Electrophysiological and anatomical techniques were used to investigate normal and regenerating sural and posterior femoral cutaneous nerve fibres in the cat. 2. One and a half years after transection of these nerves it was found that the regenerating neurones supported multiple sprouts in the... | Nerve fibres; Transection; Nerve injury | 1981 |
| 14 |
 | Christensen, Douglas A. | Planar waveguide biosensors for nucleic acid hybridization reactions | Oligonucleotide probes derived from (1) the T3 RNA polymerase promoter sequence (T3) and (2) prostate-specific antigen messenger RNA (PSA) were prepared and labeled with a red-emitting fluorescent dye (Cy5). The complimentary oligonucleotides (anti T3 and anti PSA) were prepared and labeled with bio... | Planar waveguides; Evanescence; Fluorescence; Glandular kallikrein; MDx; Molecular diagnostics; Nucleic acid; PSA; Oligonucleotide probes | 2000 |
| 15 |
 | Baehr, Wolfgang; Prestwich, Glenn D. | Photoreceptor cGMP phosphodiesterase delta subunit (PDEdelta) functions as a prenyl-binding protein | Bovine PDEdelta was originally copurified with rod cGMP phosphodiesterase (PDE) and shown to interact with prenylated, carboxymethylated C-terminal Cys residues. Other studies showed that PDEdelta can interact with several small GTPases including Rab13, Ras, Rap, and Rho6, all of which are prenylate... | Fluorescence Resonance Energy Transfer; GTP Phosphohydrolases; Immunohistochemistry | 2004 |
| 16 |
 | Horch, Kenneth W.; Christensen, Douglas A. | Accelerated 4-year bachelors/masters degree program in biomedical engineering | In response to the need for providing advanced engineering education in a shorter time period than is currently possible by traditional curricula, we have created an Accelerated Dual Degree program in biomedical engineering. The purpose of this pilot program is to attract the brightest students, g... | Accelerated; Dual-degrees; Education | 2002 |
| 17 |
 | Christensen, Douglas A. | Bringing an integrative modeling experience to a freshman biomedical engineering course | As an integrating lab experience in our Fundamentals of Bioengineering freshman course, we have included a Major Project that ties together many of the principles of biomechanics and bioelectricity covered in the lecture. It uses the human systemic cardiovascular system as a model. During the first... | Matlab | 2004 |
| 18 |
 | Christensen, Douglas A. | Finite-difference time-domain modeling and experimental characterization of planar waveguide fluorescence sensors | The finite-difference time-domain method (FDTD) is a powerful numerical technique for solving Maxwell's equations in a discretized space and time grid. Its applications have up to now been in the analysis of electrically large structures in the microwave domain, and the scope of investigations has b... | Finite-difference time-domain method; Planar waveguide | 1992 |
| 19 |
 | Horch, Kenneth W. | Stability of chronic intrafascicular electrode recordings | We have implanted intrafascicular electrodes in peripheral nerves of cats and have recorded neural activity from a small population of nerve fibers for as long as six months, suggesting that these electrodes can be used on a chronic basis to acquire information about limb position, muscle force and ... | Intrafascicular electrodes; Electrode recordings | 1989 |
| 20 |
 | Gesteland, Raymond F. | Simian virus 40-specific polypeptides in Ad2+ND4- infected cells | A comparison of the proteins synthesized in human cells at late times after infection with adenovirus (Ad2) and with the adeno-simian virus 40 (SV40) hybrid viruses revealed polypeptides of 30,000 and 92,000 molecular weight specific for the hybrid viruses Ad2+ND1 and Ad2+ND4, respectively. Cell-fre... | Molecular Weight; Peptide Biosynthesis; RNA, Messenger; Viral Proteins | 1976 |
| 21 |
 | Christensen, Douglas A. | Dispersion effects in fiber optic interferometry | An extended analysis of the effects of uncompensated fiber dispersion on the fringe visibility of a fiber optic interferometer is developed, with particular emphasis on stellar interferometry. Both material and waveguide dispersion for single-mode, polarization-preserving fibers are considered. It... | Stellar interferometry; Fiber optics; Statistical optics | 1997 |
| 22 |
 | Christensen, Douglas A. | Laser diode coherence length variation with drive current: a tool for dispersion measurements | A visible light (670nm) laser diode was used as a variable coherence length source to measure dispersion characteristics in single-mode fibers. The diode's spectral width, measured against increasing drive current, was found to change from about 16 nanometers to less than 0.2 nanometer. The corresp... | Laser diode; Fiber interferometry | 1992 |
| 23 |
 | Gesteland, Raymond F. | Processing of adenovirus 2-induced proteins | Analysis of (35)S-methionine-labeled extracts of adenovirus 2-infected KB cells revealed 22 virus-induced polypeptide components. Most proteins of the virion were easily detected in extracts of whole cells labeled for short periods between 15 and 30 h after infection; however, several virion compone... | Adenoviridae; Viral Proteins; Protein Precursors; Methionine; Mouth Neoplasms | 1973 |
| 24 |
 | Horch, Kenneth W.; Lawrence, Steve M.; Dhillon, Gurpreet S. | Acute peripheral nerve recording characteristics of polymer-based longitudinal intrafascicular electrodes | We examined the recording characteristics of two different types of polymer-based longitudinal intrafascicular electrodes (LIFEs) in peripheral nerve: single-stranded (s-polyLIFEs) and multistranded (m-polyLIFEs). Recordings were also made from Pt-Ir wire-based electrodes (PtIrLIFEs) as a control. T... | Sciatic Nerve; Intrafascicular Electrodes, Peripheral Nerve Recording | 2004 |
| 25 |
 | Varner, Michael W.; Clark, Edward B.; Fernando, Kumari L.; Mathews, V. John | Robust estimation of fetal heart rate variability using Doppler ultrasound. | This paper presents a new measure of heart rate variability (HRV) that can be estimated using Doppler ultrasound techniques and is robust to variations in the angle of incidence of the ultrasound beam and the measurement noise. This measure employs the multiple signal characterization (MUSIC) algori... | Prenatal Ultrasonography; Fetal Heart Rate; Blood Flow Velocity; Algorithms | 2003-08 |
