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1 Gesteland, Raymond F.; Atkins, John F.; Wills, Norma M.rRNA-mRNA base pairing stimulates a programmed -1 ribosomal frameshiftBase pairing between the 3' end of 16S rRNA and mRNA is shown to be important for the programmed -1 frameshifting utilized in decoding the Escherichia coli dnaX gene. This pairing is the same as the Shine-Dalgarno pairing used by prokaryotic ribosomes in selection of translation initiators, but for ...Frameshifting; Escherichia coli; Binding Sites; Base Composition1994
2 Gesteland, Raymond F.; Atkins, John F.; Ingram, Jennifer A.; Kelly, Paul J.; Grentzmann, GuidoDual-luciferase reporter system for studying recoding signalsA new reporter system has been developed for measuring translation coupling efficiency of recoding mechanisms such as frameshifting or readthrough. A recoding test sequence is cloned in between the renilla and firefly luciferase reporter genes and the two luciferase activities are subsequently measu...Amino Acid Sequence; Genes, Reporter; HIV; Antizyme; Translation1998
3 Christensen, Douglas A.Introduction to biomedical engineering: biomechanics and bioelectricity - part IIntended as an introduction to the field of biomedical engineering, this book covers the topics of biomechanics (Part I) and bioelectricity (Part II). Each chapter emphasizes a fundamental principle or law, such as Darcy's Law, Poiseuille's Law, Hooke's Law, Starling's law, levers and work in the a...Biological membranes; Poiseuille's law; Hooke's law; Starling's law of the heart; Matlab2009
4 Christensen, Douglas A.Using the cardiovascular system to illustrate fundamental laws and principles in a freshman courseOur Fundamentals of Bioengineering I course is organized around key physical and engineering laws and principles. A semester-long Major Project is assigned which integrates many of these principles by modeling the human systemic cardiovascular system, using both Matlab computer analysis and assembly...Matlab2002
5 Normann, Richard A.; Kolb, Helga; Lasater, Eric M.Signal integration at the pedicle of turtle cone photoreceptors: an anatomical and electrophysiological studyThe morphology of the axon which connects the cell body and pedicle of turtle cone photoreceptors was studied by light and electron microscopy. The axon which contains numerous synaptic vesicles, some endoplasmic reticulum, and a few cisternae is basically filled with cytoplasm. The length of the ax...Cone Photoreceptor, Voltage Clamp; Isolated Cells; Input Resistance; Cell Body-Pedicle Coupling1989
6 Christensen, Douglas A.Introduction to biomedical engineering: biomechanics and bioelectricity - part IIIntended as an introduction to the field of biomedical engineering, this book covers the topics of biomechanics (Part I) and bioelectricity (Part II). Each chapter emphasizes a fundamental principle or law, such as Darcy's Law, Poiseuille's Law, Hooke's Law, Starling's Law, levers and work in the...Bioelectricity; Kirchhoff's voltage law; Kirchhoff's current law; Coulomb's law; Thevenin equivalent circuits; Nernst potential; Matlab2009
7 Normann, Richard A.Statistical encoding model for a primary motor cortical brain-computer interfaceA number of studies of the motor system suggest that the majority of primary motor cortical neurons represent simple movement-related kinematic and dynamic quantities in their time-varying activity patterns. An example of such an encoding relationship is the cosine tuning of firing rate with respect...Discrete Distribution; LN Model; Neural Decoding; Neuroprosthetics; Sequential Monte-Carlo Filter2005
8 Normann, Richard A.; Shoham, ShyEncoding mechanisms for sensory neurons studied with a multielectrode array in the cat dorsal root ganglionRecent advances in microelectrode array technology now permit a direct examination of the way populations of sensory neurons encode information about a limb's position in space. To address this issue, we recorded nerve impulses from about 100 single units simultaneously in the L6 and L7 dorsal root ...Sensory; Encoding; Multielectrode; Dorsal Root Ganglion; Cutaneour; Muscle2004
9 Normann, Richard A.; Branner, AlmutLong-term stimulation and recording with a penetrating microelectrode array in cat sciatic nerveWe studied the consequences of long-term implantation of a penetrating microelectrode array in peripheral nerve over the time course of 4-6 mo. Electrode arrays without lead wires were implanted to test the ability of different containment systems to protect the array and nerve during contractions o...Cats; Microelectrodes; Prosthesis Implantation; Sciatic Nerve2004
10 Horch, Kenneth W.Microfabricated cylindrical multielectrodes for neural stimulationThe effects of spinal cord injuries are likely to be ameliorated with the help of functional electrical stimulation of the spinal cord, a technique that may benefit from a new style of electrode: the cylindrical multielectrode. This paper describes the specifications for, fabrication techniques for...Cylindrical multielectrode; Depth electrodes; Impedance testing; Microelectromechanical systems (MEMS); Microstimulation; Impedance testing; Neural prosthesis2006-02
11 Horch, Kenneth W.; Tuckett, Robert P.; Burgess, Paul RichardNeural signal for skin indentation depth. I. Changing indentationsPsychophysical tests on human subjects showed that judgments of skin indentation depth made when the fingertip was indented at rates from 0.2 to 16 mm/set were quite insensitive to changes in indentation velocity. Similar results were obtained on the forearm at indentation velocities of 0.4 to 16...Skin; Indentation; Nerve impulses1983
12 Christensen, Douglas A.Effects of increased energy prices on U.S. agriculture: an econometric approachAlthough the contents of this manuscript remain the responsibility of the authors, we wish to thanks a group of reviewers for the time and conscientious effort they put forth to solidify this final draft. Andrew Morton, Brian Holding, Wesley Buchele, and Arnold Paulsen deserve much credit for their ...Energy prices1981
13 Horch, Kenneth W.Ontogeny of diving and feeding behavior in juvenile seaturtles: Leatherback Seaturtles (Dermochelys coriacea L) and Green Seaturtles (Chelonia mydas L) in the Florida CurrentWe compared activity, diving behavior and response to prey by Dermochelys coriacea and Chelonia mydas during their first 8-10 weeks of development.We reared juveniles in the laboratory and, at two-week intervals, released them in the ocean for a brief trial. Each turtle towed a device used to measur...Hatchlings; Posthatchling; Habitats2004
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