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Bender, Austin | The role of ornithine, polyamines, and amino acid accumulation in the growth of melanoma | A frequent adaptation in the development of melanoma is the downregulation of argininosuccinate synthetase 1 (ASS1), the rate limiting enzyme in the production of the amino acid arginine from citrulline and aspartate. It is known that ASS1 is required for cells to proliferate in the absence of argin... | 2024 | |
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Ward, Bridget E. | Functionalizing a hemagglutinin epitope tag for induced mitochondrial protein degradation in saccharomyces cerevisiae | Mitochondria are organelles known for their role in many critical cellular processes including the production of metabolic energy in eukaryotic cells. In order to produce this energy, mitochondria continually transport metabolites across the impermeable mitochondrial inner membrane. The transport of... | 2022 | |
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Enquist, Anneke | Discovery of platinum (II) and azulene derivative cocrystals with fluorinated cyanoaromatics | Pentacyano-trifluoromethyl benzene was synthesized using a novel technique. Before isolation, it was noted that plate like crystals had formed leading to study regarding the ability of acetic acid to co-crystallize with pentacyanotrifluoromethyl benzene. The crystal structure of acetic acid with pen... | 2024 |