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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Gerig, Guido | Early postnatal development of corpus callosum and corticospinal white matter assessed with quantitative tractography | BACKGROUND AND PURPOSE: The early postnatal period is perhaps the most dynamic phase of white matter development. We hypothesized that the early postnatal development of the corpus callosum and corticospinal tracts could be studied in unsedated healthy neonates by using novel approaches to diffusion... | 2007-01-01 | |
| 2 |
 | Gerig, Guido | Brain volumes in psychotic youth with schizophrenia and mood disorders | Background: We sought to test the hypothesis that deficits in grey matter volume are characteristic of psychotic youth with early-onset schizophrenia-spectrum disorders (EOSS) but not of psychotic youth with early-onset mood disorders (EOMD). Methods: We used magnetic resonance imaging to examine br... | 2010-01-01 | |
| 3 |
 | Gerig, Guido | Mixed-effects shape models for estimating longitudinal changes in anatomy | 2012-01-01 | ||
| 4 |
 | Gerig, Guido | Assessment of reliability of multi-site neuroimaging via traveling phantom study | This paper describes a framework for quantitative analysis of neuroimaging data of traveling human phantoms used for cross-site validation. We focus on the analysis of magnetic resonance image data including intra- and intersite comparison. Locations and magnitude of geometric deformation is studied... | 2008-01-01 | |
| 5 |
 | Gerig, Guido | Modeling 4D changes in pathological anatomy using domain adaptation: analysis of TBI imaging using a tumor database | Analysis of 4D medical images presenting pathology (i.e., lesions) is significantly challenging due to the presence of complex changes over time. Image analysis methods for 4D images with lesions need to account for changes in brain structures due to deformation, as well as the formation and deletio... | 2013-01-01 | |
| 6 |
 | Gerig, Guido | Prenatal mild ventriculomegaly predicts abnormal development of the neonatal brain | Background: Many psychiatric and neurodevelopmental disorders are associated with mild enlargement of the lateral ventricles thought to have origins in prenatal brain development. Little is known about development of the lateral ventricles and the relationship of prenatal lateral ventricle enlargeme... | 2008-01-01 | |
| 7 |
 | Gerig, Guido | Segmentation of serial MRI of TBI patients using personalized atlas construction and topological change estimation | Traumatic brain injury (TBI) due to falls, car accidents, and warfare affects millions of people annually. Determining personalized therapy and assessment of treatment efficacy can substantially benefit from longitudinal (4D) magnetic resonance imaging (MRI). In this paper, we propose a method for s... | 2012-01-01 | |
| 8 |
 | Gerig, Guido | Regional gray matter growth, sexual dimorphism, and cerebral asymmetry in the Neonatal Brain | Although there has been recent interest in the study of childhood and adolescent brain development, very little is known about normal brain development in the first few months of life. In older children, there are regional differences in cortical gray matter development, whereas cortical gray and wh... | 2007-01-01 | |
| 9 |
 | Gerig, Guido | Twin-singleton differences in neonatal brain structure | Twin studies suggest that global and regional brain volumes are highly heritable. However, estimates of heritability vary across development. Given that all twin studies are open to the potential criticism of non-generalizability due to differences in intrauterine environment between twins and singl... | 2011-01-01 | |
| 10 |
 | Gerig, Guido | Geodesic image regression with a sparse parameterization of diffeomorphisms | Image regression allows for time-discrete imaging data to be modeled continuously, and is a crucial tool for conducting statistical analysis on longitudinal images. Geodesic models are particularly well suited for statistical analysis, as image evolution is fully characterized by a baseline image an... | 2013-01-01 | |
| 11 |
 | Gerig, Guido | Tumor-induced structural radiometric asymmetry in brain images | This paper presents a general framework for analyzing structural and radiometric asymmetry in brain images. In a healthy brain, the left and right hemispheres are largely symmetric across the mid-sagittal plane. Brain tumors may belong to one or both of the following categories: mass-effect, in whic... | 2001-01-01 | |
| 12 |
 | Gerig, Guido | Modeling longitudinal MRI changes in populations using a localized, information-theoretic measure of contrast | Longitudinal MR imaging during early brain development provides important information about growth patterns and the development of neurological disorders. We propose a new framework for studying brain growth patterns within and across populations based on MRI contrast changes, measured at each time ... | 2013-01-01 | |
| 13 |
 | Gerig, Guido | Discordance of prenatal and neonatal brain development in twins | Background: Discordance of birth weight has been observed in twin pairs, though little is known about prenatal and early neonatal discordance of head and brain size, and the role that zygosity and chorionicity play in discordances of early brain development in twins. Aims: To compare prenatal and ne... | 2009-01-01 | |
| 14 |
 | Gerig, Guido | Analysis of diffusion tensor imaging for subjects with Down Syndrome | Authors: Neda Sadeghi1, Clement Vachet1, Marcel Prastawa1, Julie Korenberg1, Guido Gerig1 Institutions: 1University of Utah, Salt Lake City, UT Introduction: Down syndrome (DS) is the most common chromosome abnormality in humans. It is typically associated with delayed cognitive development and phys... | 2013-01-01 | |
| 15 |
 | Gerig, Guido | Topology preserving atlas construction from shape data without correspondence using sparse parameters | Statistical analysis of shapes, performed by constructing an atlas composed of an average model of shapes within a population and associated deformation maps, is a fundamental aspect of medical imaging studies. Usual methods for constructing a shape atlas require point correspondences across subject... | 2012-01-01 | |
| 16 |
 | Gerig, Guido | Statistical shape analysis of brain structures using spherical wavelets | We present a novel method of statistical surface-based morphometry based on the use of non-parametric permutation tests and a spherical wavelet (SWC) shape representation. As an application, we analyze two brain structures, the caudate nucleus and the hippocampus, and compare the results obtained to... | 2007-01-01 | |
| 17 |
 | Gerig, Guido | White matter microstructure and atypical visual orienting in 7 month-olds at risk for autism | Objective: The authors sought to determine whether specific patterns of oculo-motor functioning and visual orientingcharacterize 7-month-old infants who later meet criteria for an autism spectrum disorder (ASD) and to identify the neural correlates of these behaviors. Method:Data were collected from... | 2013-01-01 | |
| 18 |
 | Farrell, Timothy W. | Organizational culture associated with provider satisfaction | Background: Organizational culture is key to the successful implementation of major improvement strategies. Transformation to a patient-centered medical home (PCHM) is such an improvement strategy, requiring a shift from provider-centric care to team-based care. Because this shift may impact provide... | 2014-01-01 | |
| 19 |
 | Gerig, Guido | Statistical group differences in anatomical shape analysis using Hotelling T2 Metric | Shape analysis has become of increasing interest to the neuroimaging community due to its potential to precisely locate morphological changes between healthy and pathological structures. This manuscript presents a comprehensive set of tools for the computation of 3D structural statistical shape anal... | 2007-01-01 | |
| 20 |
 | Gerig, Guido | Changes of MR and DTI appearance in early human brain development | Understanding myelination in early brain development is of clinical importance, as many neurological disorders have their origin in early cerebral organization and maturation. The goal of this work is to study a large neonate database acquired with standard MR imagery to illuminate effects of early ... | 2010-01-01 | |
| 21 |
 | Gerig, Guido | Geodesic shape regression in the framework of currents | Shape regression is emerging as an important tool for the statistical analysis of time dependent shapes. In this paper, we develop a new generative model which describes shape change over time, by extending simple linear regression to the space of shapes represented as currents in the large deformat... | 2013-01-01 | |
| 22 |
 | Gerig, Guido | Quantifying regional growth patterns through longitudinal analysis of distances between multimodal MR intensity distributions | Quantitative analysis of early brain development through imaging is critical for identifying pathological development, which may in turn affect treatment procedures. We propose a framework for analyzing spatiotemporal patterns of brain maturation by quantifying intensity changes in longitudinal MR i... | 2012-01-01 | |
| 23 |
 | Gerig, Guido | Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline | Automated segmenting and labeling of individual brain anatomical regions, in MRI are challenging, due to the issue of individual structural variability. Although atlas-based segmentation has show its potential for both tissue and structure segmentation, due to the inherent natural variability as wel... | 2014-01-01 | |
| 24 |
 | Gerig, Guido | Correspondence evaluation in local shape analysis and structural subdivision | Regional volumetric and local shape analysis has become of increasing interest to the neuroimaging community due to the potential to locate morphological changes. In this paper we compare three common correspondence methods applied to two studies of hippocampal shape in schizophrenia: correspondence... | 2007-01-01 | |
| 25 |
 | Gerig, Guido | Statistical growth modeling of longitudinal DT-MRI for regional characterization of early brain development | A population growth model that represents the growth trajectories of individual subjects is critical to study and understand neurodevelopment. This paper presents a framework for jointly estimating and modeling individual and population growth trajectories, and determining significant regional diffe... | 2012-01-01 |