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| Creator | Title | Description | Subject | Date | ||
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Gerig, Guido | Changes of MR and DTI appearance in early human brain development | Understanding myelination in early brain development is of clinical importance, as many neurological disorders have their origin in early cerebral organization and maturation. The goal of this work is to study a large neonate database acquired with standard MR imagery to illuminate effects of early ... | 2010-01-01 | |
| 2 |
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Gerig, Guido | Early postnatal development of corpus callosum and corticospinal white matter assessed with quantitative tractography | BACKGROUND AND PURPOSE: The early postnatal period is perhaps the most dynamic phase of white matter development. We hypothesized that the early postnatal development of the corpus callosum and corticospinal tracts could be studied in unsedated healthy neonates by using novel approaches to diffusion... | 2007-01-01 | |
| 3 |
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Gerig, Guido | White matter microstructure and atypical visual orienting in 7 month-olds at risk for autism | Objective: The authors sought to determine whether specific patterns of oculo-motor functioning and visual orientingcharacterize 7-month-old infants who later meet criteria for an autism spectrum disorder (ASD) and to identify the neural correlates of these behaviors. Method:Data were collected from... | 2013-01-01 | |
| 4 |
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Gerig, Guido | Patient-tailored connectomics visualization for the assessment of white matter atrophy in traumatic brain injury | Available approaches to the investigation of traumatic brain injury (TBI) are frequently hampered, to some extent, by the unsatisfactory abilities of existing methodologies to efficiently define and represent affected structural connectivity and functional mechanisms underlying TI-related pathology.... | 2012-01-01 | |
| 5 |
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Gerig, Guido | Regional gray matter growth, sexual dimorphism, and cerebral asymmetry in the Neonatal Brain | Although there has been recent interest in the study of childhood and adolescent brain development, very little is known about normal brain development in the first few months of life. In older children, there are regional differences in cortical gray matter development, whereas cortical gray and wh... | 2007-01-01 | |
| 6 |
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Gerig, Guido | Functional connectivity MR imaging reveals cortical functional connectivity in the developing brain | BACKGROUND AND PURPOSE: Unlike conventional functional MR imaging where external sensory/cognitive paradigms are needed to specifically activate different regions of the brain, resting functional connectivity MR imaging acquires images in the absence of cognitive demands (a resting condition) and de... | 2008-01-01 | |
| 7 |
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Planelles, Vicente | An HIV-encoded antisense long non-coding RNA epigenetically regulates viral transcription | The abundance of long non-coding RNAs (lncRNAs) and their wide range of functional roles in human cells are fast becoming realized. Importantly, lncRNAs have been identified as epigenetic modulators and consequently play a pivotal role in the regulation of gene expression. A human immunodeficiency v... | 2014-01-01 | |
| 8 |
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Macleod, Robert S. | Identification and acute targeting of gaps in atrial ablation lesion sets using a real-time magnetic resonance imaging system | Background-Radiofrequency ablation is routinely used to treat cardiac arrhythmias, but gaps remain in ablation lesion sets because there is no direct visualization of ablation-related changes. In this study, we acutely identify and target gaps using a real-time magnetic resonance imaging (RT-MRI) sy... | 2012-01-01 | |
| 9 |
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Gerig, Guido | Brain volumes in psychotic youth with schizophrenia and mood disorders | Background: We sought to test the hypothesis that deficits in grey matter volume are characteristic of psychotic youth with early-onset schizophrenia-spectrum disorders (EOSS) but not of psychotic youth with early-onset mood disorders (EOMD). Methods: We used magnetic resonance imaging to examine br... | 2010-01-01 | |
| 10 |
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Gerig, Guido | A structural MRI study of human brain development from birth to two years | Brain development in the first 2 years after birth is extremely dynamic and likely plays an important role in neurodevelopmental disorders, including autism and schizophrenia. Knowledge regarding this period is currently quite limited. We studied structural brain development in healthy subjects from... | 2008-01-01 | |
| 11 |
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Gerig, Guido | Teasing apart the heterogeneity of autism: Same behavior, different brains in toddlers with fragile X syndrome and autism | To examine brain volumes in substructures associated with the behavioral features of children with FXS compared to children with idiopathic autism and controls. A cross-sectional study of brain substructures was conducted at the first time-point as part of an ongoing longitudinal MRI study of brain ... | 2009-01-01 | |
| 12 |
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Gur, Yaniv | Assessment of white matter microstructure in stroke patients using NODDI | Diffusion weighted imaging (DWI) is widely used to study changes in white matter following stroke. In various studies employing diffusion tensor imaging (DTI) and high angular resolution diffusion imaging (HARDI) modalities, it has been shown that fractional anisotropy (FA), me... | 2014-01-01 | |
| 13 |
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Gerig, Guido | Reduced relationship to cortical white matter volume revealed by Tractography-based segmentation of the corpus callosum in young children with developmental delay | Objective: The corpus callosum is the primary anatomical substrate for inter-hemispheric communication, which is important for a range of adaptive and cognitive behaviors in early development. Previous studies that have measured the corpus callosum in developmental populations have been limited by t... | 2006-01-01 | |
| 14 |
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Macleod, Robert S. | Sensitivity of epicardial electrical markers to acute ischemia detection | Introduction: We hypothesize that electrocardiographic measurements from the intramyocardial space contain more sensitive markers of ischemia than those detectable on the epicardium. The goal of this study was to evaluate different electrical markers for their potential to detect the earliest phases... | 2014-01-01 | |
| 15 |
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Gerig, Guido | Multi-object analysis of volume, pose, and shape using statistical discrimination | One goal of statistical shape analysis is the discrimination between two populations of objects. Whereas traditional shape analysis was mostly concerned with single objects, analysis of multi-object complexes presents new challenges related to alignment and pose. In this paper, we present a methodol... | 2010-01-01 | |
| 16 |
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Gerig, Guido | Prenatal mild ventriculomegaly predicts abnormal development of the neonatal brain | Background: Many psychiatric and neurodevelopmental disorders are associated with mild enlargement of the lateral ventricles thought to have origins in prenatal brain development. Little is known about development of the lateral ventricles and the relationship of prenatal lateral ventricle enlargeme... | 2008-01-01 | |
| 17 |
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Gerig, Guido | Statistical shape analysis of brain structures using spherical wavelets | We present a novel method of statistical surface-based morphometry based on the use of non-parametric permutation tests and a spherical wavelet (SWC) shape representation. As an application, we analyze two brain structures, the caudate nucleus and the hippocampus, and compare the results obtained to... | 2007-01-01 | |
| 18 |
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Kendall, Katherine | Quality of life scores compared to objective measures of swallowing function after oropharyngeal chemoradiation | Objectives: To compare objective measures of swallowing function with patient reports of swallowing-related Quality of Life one year after treatment of oropharyngeal cancer with chemoradiation therapy. Study Design: Patients seen for follow-up at least one year after treatment of oropharyngeal carci... | 2014-01-01 | |
| 19 |
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Farrell, Timothy W. | Organizational culture associated with provider satisfaction | Background: Organizational culture is key to the successful implementation of major improvement strategies. Transformation to a patient-centered medical home (PCHM) is such an improvement strategy, requiring a shift from provider-centric care to team-based care. Because this shift may impact provide... | 2014-01-01 | |
| 20 |
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Gerig, Guido | Temporal and spatial development of axonal maturation and myelination of white matter in the developing brain | BACKGROUND AND PURPOSE-Diffusion tensor imaging (DTI) has been widely used to investigate the development of white matter (WM). However, information about this development in healthy children younger than 2 years of age is lacking, and most previous studies have only measured fractional anisotropy (... | 2009-01-01 | |
| 21 |
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Solomon, Douglas Kip | Bayesian evaluation of groundwater age distribution using radioactive tracers and anthropogenic chemicals | The development of a Bayesian modeling approach for estimation of the age distribution of groundwater using radioactive isotopes and anthropogenic chemicals is described. The model considers the uncertainties associated with the measured tracer concentrations as well as the parameters affecting the ... | 2012-01-01 |
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