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Creator | Title | Description | Subject | Date |
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Awate, Suyash Prakash | Multiatlas segmentation as nonparametric regression | This paper proposes a novel theoretical framework to model and analyze the statistical characteristics of a wide range of segmentation methods that incorporate a database of label maps or atlases; such methods are termed as label fusion or multiatlas segmentation.We model these multiatlas segmentati... | | 2014-01-01 |
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Gerig, Guido | Modeling 4D changes in pathological anatomy using domain adaptation: analysis of TBI imaging using a tumor database | Analysis of 4D medical images presenting pathology (i.e., lesions) is significantly challenging due to the presence of complex changes over time. Image analysis methods for 4D images with lesions need to account for changes in brain structures due to deformation, as well as the formation and deletio... | | 2013-01-01 |
3 |
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Gerig, Guido | Analysis of longitudinal shape variability via subject specific growth modeling | Statistical analysis of longitudinal imaging data is crucial for understanding normal anatomical development as well as disease progression. This fundamental task is challenging due to the difficulty in modeling longitudinal changes, such as growth, and comparing changes across different populations... | | 2012-01-01 |
4 |
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Gerig, Guido | Constrained data decomposition and regression for analyzing healthy aging from fiber tract diffusion properties | It has been shown that brain structures in normal aging undergo significant changes attributed to neurodevelopmental and neurodegeneration processes as a lifelong, dynamic process. Modeling changes in healthy aging will be necessary to explain differences to neurodegenerative patterns observed in m... | | 2009-01-01 |
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Gerig, Guido | Changes of MR and DTI appearance in early human brain development | Understanding myelination in early brain development is of clinical importance, as many neurological disorders have their origin in early cerebral organization and maturation. The goal of this work is to study a large neonate database acquired with standard MR imagery to illuminate effects of early ... | | 2010-01-01 |
6 |
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Gerig, Guido | Unbiased diffeomorphic atlas construction for computational anatomy | Construction of population atlases is a key issue in medical image analysis, and particularly in brain mapping. Large sets of images are mapped into a common coordinate system to study intra-population variability and inter-population differences, to provide voxel-wise mapping of functional sites, a... | | 2004-01-01 |
7 |
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Gerig, Guido | Measures for validation of DTI tractography | The evaluation of analysis methods for diffusion tensor imaging (DTI) remains challenging due to the lack of gold standards and validation frameworks. Significant work remains in developing metrics for comparing fiber bundles generated from streamline tractography. We propose a set of volumetric and... | | 2012-01-01 |
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Gerig, Guido | Group statistics of DTI fiber bundles using spatial functions of tensor measures | We present a framework for hypothesis testing of differences between groups of DTI ber tracts. An anatomical, tract-oriented coordinate system provides a basis for estimating the distribution of diffusion properties. The parametrization of sampled, smooth functions is normalized across a population ... | | 2008-01-01 |
9 |
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Gerig, Guido | A framework for longitudinal data analysis via shape regression | Traditional longitudinal analysis begins by extracting desired clinical measurements, such as volume or head circumference, from discrete imaging data. Typically, the continuous evolution of a scalar measurement is estimated by choosing a 1D regression model, such as kernel regression or fitting a p... | | 2012-01-01 |
10 |
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Gerig, Guido | Abnormal vessel tortuosity as a marker of treatment response of malignant gliomas: preliminary report | Despite multiple advances in medical imaging, noninvasive monitoring of therapeutic efficacy for malignant gliomas remains problematic. An underutilized observation is that malignancy induces characteristic abnormalities of vessel shape. These characteristic shape abnormalities affect both capillari... | | 2004-01-01 |
11 |
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Gerig, Guido | Toward a comprehensive framework for the spatiotemporal statistical analysis of longitudinal shape data | This paper proposes an original approach for the statistical analysis of longitudinal shape data. The proposed method allows the characterization of typical growth patterns and subject-specific shape changes in repeated time-series observations of several subjects. This can be seen as the extension ... | | 2013-01-01 |
12 |
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Gerig, Guido | Computational anatomy to assess longitudinal trajectory of brain growth | This paper addresses the challenging problem of statistics on images by describing average and variability. We describe computational anatomy tools for building 3-D and spatio-temporal 4-D atlases of volumetric image data. The method is based on the previously published concept of unbiased atlas bui... | | 2006-01-01 |
13 |
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Gerig, Guido | Multivariate Modeling of longitudinal MRI in early brain development with confidence measures | The human brain undergoes rapid organization and structuring early in life. Longitudinal imaging enables the study of these changes over a developmental period within individuals through estimation of population growth trajectory and its variability. In this paper, we focus on maturation of white an... | | 2013-01-01 |
14 |
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Gerig, Guido | Group mean differences of voxel and surface objects via nonlinear averaging | Building of atlases representing average and variability of a population of images or of segmented objects is a key topic in application areas like brain mapping, deformable object segmentation and object classification. Recent developments in image averaging, i.e. constructing an image which is cen... | | 2006-01-01 |
15 |
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Gerig, Guido | Closed and open source neuroimage analysis tools and libraries at UNC | The emergence of open-source libraries and development tools in the last decade has changed the process of academic software development in many ways. In medical image processing and visualization this change is especially evident, also because open source projects are actively furthered by grant fu... | | 2006-01-01 |
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Planelles, Vicente | An HIV-encoded antisense long non-coding RNA epigenetically regulates viral transcription | The abundance of long non-coding RNAs (lncRNAs) and their wide range of functional roles in human cells are fast becoming realized. Importantly, lncRNAs have been identified as epigenetic modulators and consequently play a pivotal role in the regulation of gene expression. A human immunodeficiency v... | | 2014-01-01 |
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Gerig, Guido | 4D active cut: an interactive tool for pathological anatomy modeling | 4D pathological anatomy modeling is key to understanding complex pathological brain images. It is a challenging problem due to the difficulties in detecting multiple appearing and disappearing lesions across time points and estimating dynamic changes and deformations between them. We propose a novel... | | 2014-01-01 |
18 |
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Gerig, Guido | Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline | Automated segmenting and labeling of individual brain anatomical regions, in MRI are challenging, due to the issue of individual structural variability. Although atlas-based segmentation has show its potential for both tissue and structure segmentation, due to the inherent natural variability as wel... | | 2014-01-01 |
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Gerig, Guido | Diffusion tensor imaging: application to the study of the developing brain | Objective: To provide an overview of diffusion tensor imaging (DTI) and its application to the study of white matter in the developing brain, in both healthy and clinical samples. Method: The development of DTI and its application to brain imaging of white matter tracts is discussed. 48 studies usi... | | 2007-01-01 |
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Harris, Michael D. | Correlations between the alpha angle and femoral head asphericity: Implications and recommendations for the diagnosis of cam femoroacetabular impingement | Objective: To determine the strength of common radiographic and radial CT views for measuring true femoral head asphericity. Patients and Methods: In 15 patients with cam femoroacetabular impingement (FAI) and 15 controls, alpha angles were measured by two observers using radial CT (0º, 30º, 60º,... | | 2014-01-01 |
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Gerig, Guido | Mixed-effects shape models for estimating longitudinal changes in anatomy | | | 2012-01-01 |
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Gerig, Guido | Cortical enhanced tissue segmentation of neonatal brain MR images acquired by a dedicated phased array coil | The acquisition of high quality MR images of neonatal brains is largely hampered by their characteristically small head size and low tissue contrast. As a result, subsequent image processing and analysis, especially for brain tissue segmentation, are often hindered. To overcome this problem, a dedic... | | 2009-01-01 |
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Gerig, Guido | Early postnatal development of corpus callosum and corticospinal white matter assessed with quantitative tractography | BACKGROUND AND PURPOSE: The early postnatal period is perhaps the most dynamic phase of white matter development. We hypothesized that the early postnatal development of the corpus callosum and corticospinal tracts could be studied in unsedated healthy neonates by using novel approaches to diffusion... | | 2007-01-01 |
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Seyedhosseini Tarzjani, Seyed Mojtaba | Image segmentation with cascaded hierarchical models and logistic disjunctive normal networks | Contextual information plays an important role in solving vision problems such as image segmentation. However, extracting contextual information and using it in an effective way remains a difficult problem. To address this challenge, we propose a multi-resolution contextual framework, called cascade... | | 2013-01-01 |
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Gerig, Guido | Brain volumes in psychotic youth with schizophrenia and mood disorders | Background: We sought to test the hypothesis that deficits in grey matter volume are characteristic of psychotic youth with early-onset schizophrenia-spectrum disorders (EOSS) but not of psychotic youth with early-onset mood disorders (EOMD). Methods: We used magnetic resonance imaging to examine br... | | 2010-01-01 |