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CreatorTitleDescriptionSubjectDate
1 Gerig, GuidoSpatiotemporal modeling of distribution-valued data applied to DTI tract evolution in infant neurodevelopmentThis paper proposes a novel method that extends spatiotemporal growth modeling to distribution-valued data. The method relaxes assumptions on the underlying noise models by considering the data to be represented by the complete probability distributions rather than a representative, single-valued su...2013-01-01
2 Anderson, Erik WesleyDiscovering and visualizing patterns in EEG dataBrain activity data is often collected through the use of electroen-cephalography (EEG). In this data acquisition modality, the electric fields generated by neurons are measured at the scalp. Although this technology is capable of measuring activity from a group of neurons, recent efforts provide ev...2013-01-01
3 Gerig, GuidoGeodesic regression of image and shape data for improved modeling of 4D trajectoriesA variety of regression schemes have been proposed on images or shapes, although available methods do not handle them jointly. In this paper, we present a framework for joint image and shape regression which incorporates images as well as anatomical shape information in a consistent manner. Evolutio...2014-01-01
4 Gerig, GuidoSpatio-temporal analysis of early brain developmentAnalysis of human brain development is a crucial step for improved understanding of neurodevelopmental disorders. We focus on normal brain development as is observed in the multimodal longitudinal MRI/DTI data of neonates to two years of age. We present a spatio-temporal analysis framework using Gom...2010-01-01
5 Gerig, GuidoMultivariate longitudinal statistics for neonatal-pediatric brain tissue developmentThe topic of studying the growth of human brain development has become of increasing interest in the neuroimaging community. Cross-sectional studies may allow comparisons between means of different age groups, but they do not provide a growth model that integrates the continuum of time, nor do they ...2008-01-01
6 Gerig, GuidoBuilding spatiotemporal anatomical models using joint 4-D segmentation, registration, and subject-specific atlas estimationLongitudinal analysis of anatomical changes is a vital component in many personalized-medicine applications for predicting disease onset, determining growth/atrophy patterns, evaluating disease progression, and monitoring recovery. Estimating anatomical changes in longitudinal studies, especially th...2012-01-01
7 Gerig, GuidoEstimation of smooth growth trajectories with controlled acceleration from time series shape dataLongitudinal shape analysis often relies on the estimation of a realistic continuous growth scenario from data sparsely distributed in time. In this paper, we propose a new type of growth model para-meterized by acceleration, whereas standard methods typically control the velocity. This mimics the b...2011-01-01
8 Gerig, GuidoParametric regression scheme for distributions: analysis of DTI fiber tract diffusion changes in early Brain DevelopmentTemporal modeling frameworks often operate on scalar variables by summarizing data at initial stages as statistical summaries of the underlying distributions. For instance, DTI analysis often employs summary statistics, like mean, for regions of interest and properties along fiber tracts for populat...2014-01-01
9 Gerig, GuidoMixed-effects shape models for estimating longitudinal changes in anatomy2012-01-01
10 Gerig, GuidoA joint framework for 4D segmentation and estimation of smooth temporal appearance changesMedical imaging studies increasingly use longitudinal images of individual subjects in order to follow-up changes due to development, degeneration, disease progression or efficacy of therapeutic intervention. Repeated image data of individuals are highly correlated, and the strong causality of infor...2014-01-01
11 Gerig, GuidoQuality control of diffusion weighted imagesDiffusion Tensor Imaging (DTI) has become an important MRI procedure to investigate the integrity of white matter in brain in vivo. DTI is estimated from a series of acquired Diffusion Weighted Imaging (DWI) volumes. DWI data suffers from inherent low SNR, overall long scanning time of multiple dire...2010-01-01
12 Gerig, GuidoA framework for longitudinal data analysis via shape regressionTraditional longitudinal analysis begins by extracting desired clinical measurements, such as volume or head circumference, from discrete imaging data. Typically, the continuous evolution of a scalar measurement is estimated by choosing a 1D regression model, such as kernel regression or fitting a p...2012-01-01
13 Gerig, GuidoConstrained data decomposition and regression for analyzing healthy aging from fiber tract diffusion propertiesIt has been shown that brain structures in normal aging undergo significant changes attributed to neurodevelopmental and neurodegeneration processes as a lifelong, dynamic process. Modeling changes in healthy aging will be necessary to explain differences to neurodegenerative patterns observed in m...2009-01-01
14 Gerig, GuidoStatistical growth modeling of longitudinal DT-MRI for regional characterization of early brain developmentA population growth model that represents the growth trajectories of individual subjects is critical to study and understand neurodevelopment. This paper presents a framework for jointly estimating and modeling individual and population growth trajectories, and determining significant regional diffe...2012-01-01
15 Meyer, Miriah DawnDesign activity framework for visualization designAn important aspect in visualization design is the connection between what a designer does and the decisions the designer makes. Existing design process models, however, do not explicitly link back to models for visualization design decisions. We bridge this gap by introducing the design activity fr...2014-01-01
16 Gerig, GuidoLongitudinal growth modeling of discrete-time functions with application to DTI tract evolution in early neurodevelopmentWe present a new framework for spatiotemporal analysis of parameterized functions attributed by properties of 4D longitudinal image data. Our driving application is the measurement of temporal change in white matter diffusivity of fiber tracts. A smooth temporal modeling of change from a discrete-ti...2012-01-01
17 Gerig, GuidoGeodesic image regression with a sparse parameterization of diffeomorphismsImage regression allows for time-discrete imaging data to be modeled continuously, and is a crucial tool for conducting statistical analysis on longitudinal images. Geodesic models are particularly well suited for statistical analysis, as image evolution is fully characterized by a baseline image an...2013-01-01
18 Gerig, GuidoA new framework for analyzing white matter maturation in early brain developmentThe trajectory of early brain development is marked by rapid growth presented by volume but also by tissue property changes. Capturing regional characteristics of axonal structuring and myelination via neuroimaging requires analysis of longitudinal image data with multiple modalities. Complementary ...2010-01-01
19 Gerig, GuidoAssessment of reliability of multi-site neuroimaging via traveling phantom studyThis paper describes a framework for quantitative analysis of neuroimaging data of traveling human phantoms used for cross-site validation. We focus on the analysis of magnetic resonance image data including intra- and intersite comparison. Locations and magnitude of geometric deformation is studied...2008-01-01
20 Gerig, GuidoAnalysis of longitudinal shape variability via subject specific growth modelingStatistical analysis of longitudinal imaging data is crucial for understanding normal anatomical development as well as disease progression. This fundamental task is challenging due to the difficulty in modeling longitudinal changes, such as growth, and comparing changes across different populations...2012-01-01
21 Gerig, GuidoGeodesic shape regression in the framework of currentsShape regression is emerging as an important tool for the statistical analysis of time dependent shapes. In this paper, we develop a new generative model which describes shape change over time, by extending simple linear regression to the space of shapes represented as currents in the large deformat...2013-01-01
22 Gerig, GuidoA preliminary study on the effect of motion correction on HARDI reconstructionPost-acquisition motion correction is widely performed in diffusion-weighted imaging (DWI) to guarantee voxel-wise correspondence between DWIs. Whereas this is primarily motivated to save as many scans as possible if corrupted by motion, users do not fully understand the consequences of different ty...2014-01-01
23 Gerig, GuidoBrain maturation of newborns and infantsRecently, imaging studies of early human development have received more attention, as improved modeling methods might lead to a clearer understanding of the origin, timing, and nature of differences in neurodevelopmental disorders. Non-invasivemagnetic resonance imaging (MRI) can provide three-dimen...2011-01-01
24 Gur, YanivAssessment of white matter microstructure in stroke patients using NODDIDiffusion weighted imaging (DWI) is widely used to study changes in white matter following stroke. In various studies employing diffusion tensor imaging (DTI) and high angular resolution diffusion imaging (HARDI) modalities, it has been shown that fractional anisotropy (FA), me...2014-01-01
25 Gerig, GuidoToward a comprehensive framework for the spatiotemporal statistical analysis of longitudinal shape dataThis paper proposes an original approach for the statistical analysis of longitudinal shape data. The proposed method allows the characterization of typical growth patterns and subject-specific shape changes in repeated time-series observations of several subjects. This can be seen as the extension ...2013-01-01
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