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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Wunderlich, Adam James | A nonparametric procedure for comparing the areas under correlated LROC curves | In contrast to the receiver operating characteristic (ROC) assessment paradigm, localization ROC (LROC) analysis provides a means to jointly assess the accuracy of localization and detection in an observer study. In a typical multireader, multicase (MRMC) evaluation, the data sets are paired so that... | 2012-01-01 | |
| 2 |
 | Gerig, Guido | A preliminary study on the effect of motion correction on HARDI reconstruction | Post-acquisition motion correction is widely performed in diffusion-weighted imaging (DWI) to guarantee voxel-wise correspondence between DWIs. Whereas this is primarily motivated to save as many scans as possible if corrupted by motion, users do not fully understand the consequences of different ty... | 2014-01-01 | |
| 3 |
 | Gerig, Guido | A structural MRI study of human brain development from birth to two years | Brain development in the first 2 years after birth is extremely dynamic and likely plays an important role in neurodevelopmental disorders, including autism and schizophrenia. Knowledge regarding this period is currently quite limited. We studied structural brain development in healthy subjects from... | 2008-01-01 | |
| 4 |
 | Seyedhosseini Tarzjani, Seyed Mojtaba | A workflow for the automatic segmentation of organelles in electron microscopy image stacks | Electron microscopy(EM) facilitates analysis of the form,distribution, and functional status of key organelle systems in various pathological processes,including those associated with neurodegenerative disease.Such EM data often provide important new in sights into the underlying disease mechanisms.... | 2014-01-01 | |
| 5 |
 | Gerig, Guido | Abnormal vessel tortuosity as a marker of treatment response of malignant gliomas: preliminary report | Despite multiple advances in medical imaging, noninvasive monitoring of therapeutic efficacy for malignant gliomas remains problematic. An underutilized observation is that malignancy induces characteristic abnormalities of vessel shape. These characteristic shape abnormalities affect both capillari... | 2004-01-01 | |
| 6 |
 | Maas, Steve | Accuracy and feasibility of dual fluoroscopy and model-based tracking to quantify in vivo hip kinematics during clinical exams | Accurate measurements of in-vivo hip kinematics may elucidate the mechanisms responsible for impaired function and chondrolabral damage in hips with femoroacetabular impingement (FAI). The objectives of this study were to quantify the accuracy and demonstrate the feasibility of using dual fluoroscop... | 2014-01-01 | |
| 7 |
 | Sanderson, Allen Reed | An alternative formulation of lyapunov exponents for computing lagrangian coherent structures | Lagrangian coherent structures are time-evolving surfaces that highlight areas in flow fields where neighboring advected particles diverge or converge. The detection and understanding of such structures is an important part of many applications such as in oceanography where there is a need to predic... | 2014-01-01 | |
| 8 |
 | Planelles, Vicente | An HIV-encoded antisense long non-coding RNA epigenetically regulates viral transcription | The abundance of long non-coding RNAs (lncRNAs) and their wide range of functional roles in human cells are fast becoming realized. Importantly, lncRNAs have been identified as epigenetic modulators and consequently play a pivotal role in the regulation of gene expression. A human immunodeficiency v... | 2014-01-01 | |
| 9 |
 | Gerig, Guido | Analysis of diffusion tensor imaging for subjects with Down Syndrome | Authors: Neda Sadeghi1, Clement Vachet1, Marcel Prastawa1, Julie Korenberg1, Guido Gerig1 Institutions: 1University of Utah, Salt Lake City, UT Introduction: Down syndrome (DS) is the most common chromosome abnormality in humans. It is typically associated with delayed cognitive development and phys... | 2013-01-01 | |
| 10 |
 | Gerig, Guido | Analysis of longitudinal shape variability via subject specific growth modeling | Statistical analysis of longitudinal imaging data is crucial for understanding normal anatomical development as well as disease progression. This fundamental task is challenging due to the difficulty in modeling longitudinal changes, such as growth, and comparing changes across different populations... | 2012-01-01 | |
| 11 |
 | Gerig, Guido | Analyzing imaging biomarkers for traumatic brain injury using 4D modeling of longitudinal MRI | Quantitative imaging biomarkers are important for assessment of impact, recovery and treatment efficacy in patients with traumatic brain injury (TBI). To our knowledge, the identification of such biomarkers characterizing disease progress and recovery has been insufficiently explored in TBI due to d... | 2013-01-01 | |
| 12 |
 | Gerig, Guido | Assessment of reliability of multi-site neuroimaging via traveling phantom study | This paper describes a framework for quantitative analysis of neuroimaging data of traveling human phantoms used for cross-site validation. We focus on the analysis of magnetic resonance image data including intra- and intersite comparison. Locations and magnitude of geometric deformation is studied... | 2008-01-01 | |
| 13 |
 | Gur, Yaniv | Assessment of white matter microstructure in stroke patients using NODDI | Diffusion weighted imaging (DWI) is widely used to study changes in white matter following stroke. In various studies employing diffusion tensor imaging (DTI) and high angular resolution diffusion imaging (HARDI) modalities, it has been shown that fractional anisotropy (FA), me... | 2014-01-01 | |
| 14 |
 | Gerig, Guido | Automatic corpus callosum segmentation using a deformable active Fourier contour model | The corpus callosum (CC) is a structure of interest in many neuroimaging studies of neuro-developmental pathology such as autism. It plays an integral role in relaying sensory, motor and cognitive information from homologous regions in both hemispheres. We have developed a framework that allows auto... | 2012-01-01 | |
| 15 |
 | Gerig, Guido | Brain maturation of newborns and infants | Recently, imaging studies of early human development have received more attention, as improved modeling methods might lead to a clearer understanding of the origin, timing, and nature of differences in neurodevelopmental disorders. Non-invasivemagnetic resonance imaging (MRI) can provide three-dimen... | 2011-01-01 | |
| 16 |
 | Gerig, Guido | Brain volumes in psychotic youth with schizophrenia and mood disorders | Background: We sought to test the hypothesis that deficits in grey matter volume are characteristic of psychotic youth with early-onset schizophrenia-spectrum disorders (EOSS) but not of psychotic youth with early-onset mood disorders (EOMD). Methods: We used magnetic resonance imaging to examine br... | 2010-01-01 | |
| 17 |
 | Gerig, Guido | Building spatiotemporal anatomical models using joint 4-D segmentation, registration, and subject-specific atlas estimation | Longitudinal analysis of anatomical changes is a vital component in many personalized-medicine applications for predicting disease onset, determining growth/atrophy patterns, evaluating disease progression, and monitoring recovery. Estimating anatomical changes in longitudinal studies, especially th... | 2012-01-01 | |
| 18 |
 | Gerig, Guido | Changes of MR and DTI appearance in early human brain development | Understanding myelination in early brain development is of clinical importance, as many neurological disorders have their origin in early cerebral organization and maturation. The goal of this work is to study a large neonate database acquired with standard MR imagery to illuminate effects of early ... | 2010-01-01 | |
| 19 |
 | Gerig, Guido | Characterizing growth patterns in longitudinal MRI using image contrast | Understanding the growth patterns of the early brain is crucial to the study of neuro-development. In the early stages of brain growth, a rapid sequence of biophysical and chemical processes take place. A crucial component of these processes, known as myelination, consists of the formation of a myel... | 2014-01-01 | |
| 20 |
 | Gerig, Guido | Closed and open source neuroimage analysis tools and libraries at UNC | The emergence of open-source libraries and development tools in the last decade has changed the process of academic software development in many ways. In medical image processing and visualization this change is especially evident, also because open source projects are actively furthered by grant fu... | 2006-01-01 | |
| 21 |
 | Gerig, Guido | Computational anatomy to assess longitudinal trajectory of brain growth | This paper addresses the challenging problem of statistics on images by describing average and variability. We describe computational anatomy tools for building 3-D and spatio-temporal 4-D atlases of volumetric image data. The method is based on the previously published concept of unbiased atlas bui... | 2006-01-01 | |
| 22 |
 | Gerig, Guido | Constrained data decomposition and regression for analyzing healthy aging from fiber tract diffusion properties | It has been shown that brain structures in normal aging undergo significant changes attributed to neurodevelopmental and neurodegeneration processes as a lifelong, dynamic process. Modeling changes in healthy aging will be necessary to explain differences to neurodegenerative patterns observed in m... | 2009-01-01 | |
| 23 |
 | Harris, Michael D. | Correlations between the alpha angle and femoral head asphericity: Implications and recommendations for the diagnosis of cam femoroacetabular impingement | Objective: To determine the strength of common radiographic and radial CT views for measuring true femoral head asphericity. Patients and Methods: In 15 patients with cam femoroacetabular impingement (FAI) and 15 controls, alpha angles were measured by two observers using radial CT (0º, 30º, 60º,... | 2014-01-01 | |
| 24 |
 | Gerig, Guido | Correspondence evaluation in local shape analysis and structural subdivision | Regional volumetric and local shape analysis has become of increasing interest to the neuroimaging community due to the potential to locate morphological changes. In this paper we compare three common correspondence methods applied to two studies of hippocampal shape in schizophrenia: correspondence... | 2007-01-01 | |
| 25 |
 | Gerig, Guido | Cortical enhanced tissue segmentation of neonatal brain MR images acquired by a dedicated phased array coil | The acquisition of high quality MR images of neonatal brains is largely hampered by their characteristically small head size and low tissue contrast. As a result, subsequent image processing and analysis, especially for brain tissue segmentation, are often hindered. To overcome this problem, a dedic... | 2009-01-01 |