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Symons, John David | Influence of folate on arterial permeability and stiffness in the absence or presence of hyperhomocysteinemia | Elevation of plasma total homocysteine (tHcy) is associated with an increased risk of cardiovascular disease, but the underlying mechanisms are not well understood.1 Worldwide, the most common cause of mild hyperhomocysteinemia (HHcy) is deficiency of folate.2,3 Some4-8 but not all9,10 studies sugg... | Cystathionine B-synthase; Carotid artery; Aorta; Cardiovascular risk factors; Folate; Hyperhomocysteinemia; Arterial permeability; Arterial stiffness | 2006 |
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Symons, John David; Jalili, Thunder; Litwin, Sheldon E. | Quercetin-supplemented diets lower blood pressure and attenuate cardiac hypertrophy in rats with aortic constriction | Quercetin (Q), a flavonoid found in berries and onions, can reduce blood pressure in hypertensive animals and inhibit signal transduction pathways in vitro that regulate cardiac hypertrophy. We hypothesized that quercetin could prevent cardiovascular complications in rats with abdominal aortic con... | | 2006 |