Filters: Date: "2004-02-13" Collection: ir_uspace
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Capecchi, Mario R. | Role of the N-terminal catalytic domain of angiotensin-converting enzyme investigated by targeted inactivation in mice | Angiotensin-converting enzyme (ACE) produces the vasoconstrictor angiotensin II. The ACE protein is composed of two homologous domains, each binding zinc and each independently catalytic. To assess the physiologic significance of the two ACE catalytic domains, we used gene targeting in mice to int... | 2004-02-13 |
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