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| Creator | Title | Description | Subject | Date | ||
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Baehr, Wolfgang | Annotation and analysis of 10,000 expressed sequence tags from 3 mouse eye cDNA libraries | BACKGROUND: As a biomarker of cellular activities, the transcriptome of a specific tissue or cell type during development and disease is of great biomedical interest. We have generated and analyzed 10,000 expressed sequence tags (ESTs) from three mouse eye tissue cDNA libraries: embryonic day 15.5 (... | Cluster Analysis; DNA, Complementary; Gene Expression Profiling | 2003 |
| 2 |
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Schmidt, Meic H.; Apfelbaum, Ronald I. | Cervical spinal metastasis: anterior reconstruction and stabilization techniques after tumor resection | Object. In a review of the literature, the authors provide an overview of various techniques that have evolved for reconstruction and stabilization after resection for metastatic disease in the subaxial cervical spine. Methods. Reconstruction and stabilization of the cervical spine after vertebral... | Cervical spine reconstruction; Metastasis; Spine tumor; Corpectomy; Stabilization technique; Vertebral body | 2003 |
| 3 |
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Schmidt, Meic H. | Diagnosis and management of sacral Tarlov cysts | Perineurial (Tarlov) cysts are meningeal dilations of the posterior spinal nerve root sheath that most often affect sacral roots and can cause a progressive painful radiculopathy. Tarlov cysts are most commonly diagnosed by lumbosacral magnetic resonance imaging and can often be demonstrated by com... | Tarlov cysts; Meningeal dilations; Spinal lesion; Outcome | 2003 |
| 4 |
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Schmidt, Meic H. | Diffuse large B-cell lymphoma presenting as a sacral tumor | Primary lymphomas of the sacrum are rare tumors, reported only in a few cases in the literature. The authors describe two patients with diffuse large B-cell lymphomas presenting as a sacral tumor. In the first case a 52-year-old man presented with progressive back pain, bilateral radicular pain, an... | B-cell lymphoma; Sacral tumor | 2003 |
| 5 |
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Baehr, Wolfgang; Zhang, Kang | Elovl4 mRNA distribution in the developing mouse retina and phylogenetic conservation of Elovl4 genes | PURPOSE: Stargardt-like macular dystrophy (STGD3) is an autosomal dominant form of early onset macular degeneration. The disease causing gene ELOVL4 encodes a protein that belongs to a family of proteins functioning in elongation of long chain fatty acids. The purpose of this study is to characteriz... | Amino Acid Sequence; Cloning, Molecular; Molecular Sequence Data | 2003 |
| 6 |
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Schmidt, Meic H. | Embolization of sacral tumors | The management of sacral tumors is challenging because of difficulties in accessing the lesion, the high rate of local recurrence, extensive vascularity causing significant intraoperative blood loss, resistance to radiation therapy, and risk of malignant transformation. Although surgery is the main ... | Sacral tumor | 2003 |
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Couldwell, William T.; Orlandi, Richard R.; Jensen, Randy L. | Endoscopic-assisted craniofacial resection of esthesioneuroblastoma: minimizing facial incisions | The surgical management of esthesioneuroblastomas has traditionally been craniofacial resection, which combines a bifrontal craniotomy with a transfacial approach. The latter usually involves a disfiguring facial incision, mid-facial degloving, lateral rhinotomy, and/or extensive facial osteotomies... | Esthesioneuroblastoma; Craniofacial resection; Endoscope; Craniofacial surgery; Minimally invasive | 2003 |
| 8 |
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Couldwell, William T.; Schmidt, Meic H.; MacDonald, Joel D.; Jensen, Randy L. | Hypophysial transposition (hypophysopexy) for radiosurgical treatment of pituitary tumors involving the cavernous sinus | Stereotactic radiosurgery (SRS) is performed with increasing frequency in the treatment of residual or recurrent pituitary adenomas. Its major associated risk in these cases of residual or recurrent pituitary tumor adjacent to normal functional pituitary gland is radiation exposure to the pituitary,... | Pituitary tumor; Cavernous sinus; Hypopituitarism; Stereotactic radiosurgery; Transsphenoidal surgery; Pituitary transposition | 2003 |
| 9 |
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Schmidt, Meic H.; MacDonald, Joel D.; Jensen, Randy L.; Couldwell, William T. | Hypophysial transposition (hypophysopexy) for radiosurgical treatment of pituitary tumors involving the cavernous sinus | Stereotactic radiosurgery (SRS) is performed with increasing frequency in the treatment of residual or recurrent pituitary adenomas. Its major associated risk in these cases of residual or recurrent pituitary tumor adjacent to normal functional pituitary gland is radiation exposure to the pituitary,... | Hypophysial transposition; Hypophysopexy; Pituitary tumors; Stereotactic radiosurgery; Pituitary transposition; Hypopituitarism | 2003 |
| 10 |
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Baehr, Wolfgang | Identification and light-dependent translocation of a cone-specific antigen, (Cone Arrestin) recognized by monoclonal antibody 7G6 | PURPOSE: To elucidate the antigen recognized by monoclonal antibody (mAb) 7G6, a widely used cone-specific marker. METHODS: 7G6 immunocytochemistry was performed on sections of human, primate, and bovine retina. The antigen was immunoprecipitated from human retinal lysates and purified with protein ... | Cones (Retina); Molecular Sequence Data; Phototransduction | 2003 |
| 11 |
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Hobbs, Maurine R.; Granger, Donald Lee | Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population | Polymorphisms in the inducible nitric oxide synthase gene (NOS2) promoter have been associated with clinical outcome from malaria. These include a CCTTT repeat (CCTTTn) 2.5 kilobases upstream from the NOS2 transcription start site, and two single nucleotide substitutions: G-->C at position -954 (G-9... | Papua New Guinea; Oceanic Ancestry Group; Repetitive Sequences, Nucleic Acid | 2003 |
| 12 |
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Dailey, Andrew T.; Brodke, Darrel S. | Inter- and intraobserver reliability of computed tomography in assessment of thoracic pedicle screw placement | Study Design. Reliability study of computed tomography imaging in 12 cadaver specimens instrumented with titanium or stainless steel thoracic pedicle screws. Objective. To evaluate inter- and intraobserver reliability of computed tomography scan in determining the accuracy of thoracic pedicle sc... | Thoracic pedicle screw; Placement; Assessment; Computed tomography | 2003 |
| 13 |
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Kestle, John R. W. | Lack of benefit of endoscopic ventriculoperitoneal shunt insertion: a multicenter randomized trial | Object. Endoscopically assisted ventricular catheter placement has been reported to reduce shunt failure in uncontrolled series. The authors investigated the efficacy of this procedure in a prospective multicenter randomized trial. Methods. Children younger than 18 years old who were scheduled for t... | Ventriculoperitoneal shunt; Shunt insertion; Shunt failure | 2003 |
| 14 |
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Baehr, Wolfgang | Light-dependent redistribution of visual arrestins and transducin subunits in mice with defective phototransduction | PURPOSE: The light-dependent redistribution of phototransduction components in photoreceptor cells plays a role in light adaptation. Upon illumination, rod and cone arrestins (Arr and cArr) translocate from the inner to the outer segments while transducin subunits (Talpha, Tbetagamma) translocate in... | Phototransduction; Protein Kinases; Rhodopsin Kinase | 2003 |
| 15 |
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Schmidt, Meic H. | Lumbosacral ependymomas: a review of the management of intradural and extradural tumors | Object. The goal of this study was to review the management of intra- and extradural ependymomas. Spinal ependymomas most commonly occur as intramedullary tumors throughout the spinal axis. In the lumbosacral region, ependymomas are most commonly associated with the conus medullaris and cauda equina... | Intradural ependymoma; Extradural ependymoma; Lumbosacral lesion | 2003 |
| 16 |
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Schmidt, Meic H.; Schmidt, Richard H. | Nerve sheath tumors involving the sacrum | Nerve sheath tumors that involve the sacrum are rare. Delayed presentation is common because of their slow-growing nature, the permissive surrounding anatomical environment, and nonspecific symptoms. Consequently, these tumors are usually of considerable size at the time of diagnosis. The authors di... | Nerve sheath tumor; Schwannoma | 2003 |
| 17 |
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Schmidt, Meic H. | Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project | In many new clinical trials of patients with malignant gliomas surgical intervention is incorporated as an integral part of tumor-directed interstitial therapies such as gene therapy, biodegradable wafer placement, and immunotherapy. Assessment of toxicity is a major component of evaluating these no... | Perioperative complications; Neurological outcomes; Glioma Outcome Project | 2003 |
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Couldwell, William T. | Pituitary apoplexy: diagnosis and management | Pituitary apoplexy, an uncommon complication of pituitary adenomas, was first decribed in 1898 when pearce Bailey reported hemorrhage into a pituitary adenoma in a 50 year old man with acromegaly. The patient presented with sudden onset of headache, nausea, vomiting, fever, oculomotor palsies, and v... | Pituitary Apoplexy; Pituitary adenoma; Transsphenoidal surgery | 2003 |
| 19 |
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Schmidt, Meic H. | Repeated operations for infiltrative low-grade gliomas without intervening therapy | Progression of infiltrative low-grade gliomas (LGGs) has been reported previously. The limitations of such studies include diverse histological grading systems, intervening therapy, and the lack of histological confirmation of malignant tumor progression. The aim of this study was to determine tumo... | Infiltrative low-grade gliomas; LGG; Tumor progression; Repeated operations; Tumor recurrence | 2003 |
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Schmidt, Meic H. | Spinal meningiomas: surgical management and outcome | Advances in imaging and surgical technique have improved the treatment of spinal meningiomas; these include magnetic resonance imaging, intraoperative ultrasonography, neuromonitoring, the operative microscope, and ultrasonic cavitation aspirators. This study is a retrospective review of all patient... | Spinal meningioma; Spinal tumor; Intradural; Extramedullary | 2003 |
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Larson, Scott A. | Strabismus surgery complications: prevention and management | Strabismus surgery is increasingly becoming a subspecialty domain, especially with cyclovertical muscles, restricted muscles, or reoperations. While is impossible to completely eliminate complications from strabimus surgery, it is possible to minimize their occurrence and significance by proper prev... | Malignant hyperthermia; Overcorrection; Strabismus; Surgery; Undercorrection | 2003 |
| 22 |
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Schmidt, Meic H.; Brockmeyer, Douglas Lee; Dailey, Andrew T. | Surgical management of aneurysmal bone cysts of the spine | Object. Aneurysmal bone cysts of the spine are benign, highly vascular osseous lesions of unknown origin that may present difficult diagnostic and therapeutic challenges. They are expansile lesions containing thin-walled, blood-filled cystic cavities that cause bone destruction and sometimes spinal ... | Aneurysmal bone cyst; Spine tumor; Spinal fusion; Embolization | 2003 |
| 23 |
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Kestle, John R. W. | Tracking resident work hours: available software is not yet ideal, but it's helpful | An ideal system would be completely passive and would allow more detailed tracking of activity inside the hospital. A new reality began July 1. We are all now responsible for tracking our residents' work hours and ensuring compliance with the new regulations mandated by the Accreditation Council fo... | Resident work hours; Tracking; TimeClock system | 2003 |
| 24 |
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Schmidt, Meic H.; Kestle, John R. W. | Treatment of metastatic spinal epidural disease: a review of the literature | Object. Spinal cord compression is one of the most dreaded complications of metastatic cancer. It can lead to a number of sequelae, including pain, spinal instability, neurological deficits, and a reduction in the patient's quality of life. Except in selected circumstances, treatment is palliative. ... | Spinal cord compression; Metastasis; Radiation therapy; Stereotactic radiosurgery | 2003 |
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Couldwell, William T. | Zones of approach for craniofacial resection: minimizing facial incisions for resection of anterior cranial base and paranasal sinus tumors | Anterior cranial base tumors are surgically resected with combined craniofacial approaches that frequently involve disfiguring facial incisions and facial osteotomies. The authors outline three operative zones of the anterior cranial base and paranasal sinuses in which tumors can be resected with th... | Anatomic study; Anterior cranial base; Cranial base surgery; Craniofacial surgery; Minimally invasive | 2003 |
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