Filters: Date: "2002" Department: "Ophthalmology" School Or College: "School of Medicine" Collection: ir_uspace
1 - 25 of 6
| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
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Baehr, Wolfgang | Cloning of frog rod photoreceptor cGMP phosphodiesterase subunits (P-alpha, P-beta, P-gamma) and identification of P-gamma) sites involved in the stimulation of cGMP binding to P-alpha and P-beta non-catalytic sites | Retinal cGMP phosphodiesterase (PDE6) is a key enzyme in vertebrate phototransduction. Rod PDE contains two homologous catalytic subunits (Pd two identical regulatory subunits (P). Biochemical studies have shown that amphibian P has high affinity, cGMP-specific, non-catalytic binding sites and that ... | Phototransduction; Retinal cGMP phosphodiesterase; Amphibian PDE | 2002 |
| 2 |
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Bernstein, Paul S.; Leppert, Mark F. | Genotype-phenotype analysis of ABCR variants in macular degeneration probands and siblings | PURPOSE: Single-copy variants of the autosomal recessive Stargardt disease (STGD1) gene ABCR (ABCA4) have been shown to confer enhanced susceptibility to age-related macular degeneration (AMD). To investigate the role of ABCR alleles in AMD further, genotype-phenotype analysis was performed on sibli... | DNA Mutational Analysis; Nuclear Family; Phenotype | 2002 |
| 3 |
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Olson, Randall J. | Microphaco update | Microphacoemulsification, or cataract surgery using ultrasound through two small stab incisions. Wound burn is now not a problem with AMO's Sovereign system plus Whitestar technology. | Microphacoemulsification; Wound Burn; Cataract Extraction | 2002 |
| 4 |
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Jones, Bryan W. | Molecular phenotyping of retinal ganglion cells | Classifying all of the ganglion cells in the mammalian retina has long been a goal of anatomists, physiologists, and cell biologists. The rabbit retinal ganglion cell layer was phenotyped using intrinsic small molecule signals (aspartate, glutamate, glycine, glutamine, GABA, and taurine) and glutama... | Aspartic Acid/metabolism; Image Cytometry/methods | 2002 |
| 5 |
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Bernstein, Paul S. | Transformations of selected carotenoids in plasma, liver, and ocular tissues of humans and in nonprimate animal models | PURPOSE: To determine the stereochemistry of carotenoids in human ocular tissues in comparison with plasma and liver and to elucidate the possible transformations of dietary (3R,3'R,6'R)-lutein and (3R,3'R)-zeaxanthin in the eye. Similarly, to characterize the carotenoid profiles in the eye tissues,... | Chromatography, High Pressure Liquid; Stereoisomerism; Xanthophylls | 2002 |
| 6 |
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Kriesel, John D.; Spruance, Spotswood L. | Treatment of herpes simplex labialis. | Recurrent herpes simplex labialis is associated with mild morbidity, but remains a significant problem for people with frequent and/or severe recurrences. Both topical and peroral episodic antiviral treatments of recurrences are modestly effective at reducing the duration of signs and symptoms. Rece... | Randomized Controlled Trials; Steroids; Drug Administration Routes | 2002 |
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