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Creator | Title | Description | Subject | Date |
126 |
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Jorgensen, Erik | Wormwholes: a commentary on K. F. Schaffner's "Genes, behavior, and developmental emergentism | Although Caenorhabditis elegans was chosen and modified to be an organism that would facilitate a reductionist program for neurogenetics, recent research has provided evidence for properties that are emergent from the neurons. While neurogenetic advances have been made using C elegans which may be u... | Organism; Neurons; Genotype | 1998 |
127 |
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Olivera, Baldomero M.; Hillyard, David R.; Gray, William Robert | ĸ-Conotoxin PVIIA is a peptide inhibiting the Shaker K+ channel | ĸ-Conotoxin PVIIA (k-PVIIA), a 27-amino acid toxin from Conus purpurascens venom that inhibits the Shaker potassium channel, was chemically synthesized in a biologically active form. The disulfide connectivity of the peptide was determined. ĸ-Conotoxin PVIIA has the following structure. | Conotoxins; k-Conotoxin PVIIA; Conus purpurascens | 1998 |
128 |
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Olivera, Baldomero M.; ; McIntosh, J. Michael | α-Conotoxin AuIB selective blocks α3ß4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release | Neuronal nicotinic acetylcholine receptors (nAChRs) with putative α3ß4-subunits have been implicated in the mediation of signaling in various systems, including ganglionic transmission peripherally and nicotine-evoked neurotransmitter release centrally. However, progress in the characterization of... | Conotoxins; a-Conotoxin AuIB; Norepinephrine release | 1998 |
129 |
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Olivera, Baldomero M.; Gray, William Robert; Hillyard, David R. | μ-Conotoxin PIIIA, a new peptide for discriminating among tetrodotoxin-sensitive Na channel subtypes | We report the characterization of a new sodium channel blocker, m-conotoxin PIIIA (m-PIIIA). The peptide has been synthesized chemically and its disulfide bridging pattern determined. | Conotoxins; m-Conotoxin PIIIA; Sodium channel blockers | 1998 |