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Creator | Title | Description | Subject | Date |
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| AAMC Award for Distinguished Research presentation for 1998 | This is a 3 minutes, 51 seconds video of the presentation of the American Association of Medical Colleges' Award for Distinguished Research to Mario Capecchi and Oliver Smithies for their independent work as pioneers in gene targeting. | Transgenic mice; Gene targeting; Genetic engineering; Mutagenesis; Capecchi, Mario R.; Science - Awards - United States; Smithies, Oliver; Awards presentations | 1998 |
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Ehleringer, James R. | Carbon isotope dynamics in Abies amabilis stands in the Cascades | Carbon isotope ratios (d13C) of canopy air and carbon isotope discrimination at the ecosystem level were studied in three montane Pacific silver fir (Abies amabilis (Dougl. ex Loud.) Dougl. ex J. Forbes) stands, an old-growth and two younger stands. Spatial and temporal variations of canopy CO2 con... | Carbon isotopes; Pacific silver fir; Carbon budget; Soil respiration; Cascade Mountains | 1998 |
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Ehleringer, James R. | Carbon isotope ratios of Atacama Desert plants reflect hyperaridity of region in northern Chile | Leaf carbon isotope ratios were measured on plants from the coastal portions of the Atacama Desert at Pan de Azucar and Paposo, Chile. Most species possessed C3 photosynthesis, although there were several CAM species, indications of some facultative CAM species, and only one C4 species. The carbon i... | Atacama Desert; Carbon isotope ratio; Intercellular carbon dioxide concentration; Hyperaridity | 1998 |
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Gesteland, Raymond F.; Atkins, John F.; Ingram, Jennifer A.; Kelly, Paul J.; Grentzmann, Guido | Dual-luciferase reporter system for studying recoding signals | A new reporter system has been developed for measuring translation coupling efficiency of recoding mechanisms such as frameshifting or readthrough. A recoding test sequence is cloned in between the renilla and firefly luciferase reporter genes and the two luciferase activities are subsequently measu... | Amino Acid Sequence; Genes, Reporter; HIV; Antizyme; Translation | 1998 |
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Davidson, Diane W. | Effects of trenching on growth and survival of planted Shorea parvifolia seedlings under pioneer stands in a logged-over forest | Effects of trenching on growth and survival of planted Shorea parvifolia seedlings under pioneer stands in a logged-over forest. We conducted an experiment to determine the value of trenching in reducing potentially negative effects of root competition on growth of Shorea parvifolia seedlings plant... | Shorea parvifolia; Trenching; Dipterocarp seedlings; Enrichment planting; Pioneer stands; Root competition; Soil compaction; Sabah | 1998 |
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Hughes, Kelly T. | Flagellar anti-σ factor FlgM actively dissociates Salmonella typhimurium σ28 RNA polymerase holoenzyme | The anti-σ factor FlgM of Salmonella typhimurium inhibits transcription of class 3 flagellar genes through a direct interaction with the flagellar-specific σ factor, σ28. FlgM is believed to prevent RNA polymerase (RNAP) holoenzyme formation by sequestering free σ28. We have analyzed FlgM-media... | sigma-factors; transcription; FlgM; Flagellum | 1998 |
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Capecchi, Mario R. | Gene targeting: an historical perspective | Our entry into what was going to become the field of gene targeting began in 1977. I was experimenting with the use of extremely small glass needles to inject DNA directly into the nuclei of living cells. The needles were controlled by hydraulically driven micro-manipulators and were directed into n... | Gene targeting -- History; Homologous recombination | 1998 |
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| Genetics in Utah : NPR talk of the nation, science Friday for May 15, 1998 | This is a 1 hour, 9 seconds audio transcript of National Public Radio's Science Friday that was taped at Westminster College of Salt Lake on 1998/05/15. The host, Ira Flatow, leads a panel composed of University of Utah scientists and researchers, Jeffrey Bodkin, Mario Capecchi, Ray Gesteland, Mark... | Genetic engineering; Molecular genetics; Capecchi, Mario R.; Homeobox genes; Science - Moral and ethical aspects; Human chromosome abnormalities - Diagnosis | 1998 |
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Beckerle, Mary C. | Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains | Drosophila Enabled (Ena) was initially identified as a dominant genetic suppressor of mutations in the Abelson tyrosine kinase and, more recently, as a member of the Ena/human vasodilator-stimulated phosphoprotein (VASP) family of proteins. We have used genetic, biochemical, and cell biological appr... | Drosophila Ena; VASP | 1998 |
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Davidson, Diane W. | Nonnative brome grasses in the new national monument | Included within the boundaries of the Grand-Staircase Escalante National Monument are a number of noxious weeds for which the BLM mandates control. In addition to listed weeds are nonnative brome grasses [Bromus tectorum and Bromus rubens), which can potentially convert native ecosystems to biologic... | Noxious weeds, Cheatgrass, | 1998 |
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Goller, Franz | Ontogeny of song lateralization in juvenile northern cardinals | In adult northern cardinals (Cardinatte cardinalis), the left and right sides of the syrinx cover different vocal registers such (hat fundamental frequencies below about 3.5 or 4 kHz are produced only by the left syrinx and higher frequencies are produced primarily by the light syrinx. | Motor control; FM sweep; Subsong | 1998 |
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Ehleringer, James R. | Responses of boreal conifers to climate fluctuations: indications from tree-ring widths and carbon isotope analyses | Spatial distribution and species composition of the boreal forest are expected to change under predicted climate change scenarios. Current research indicates that water limitations control the southern boundary of the central Canadian boreal forest and temperature limitations control the northern b... | Boreal forests; Carbon budget; Picea mariana; Pinus banksiana; Carbon isotopes | 1998 |
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Goller, Franz | Vibratory behavior of the sound generating structures of the bird syrinx | Recent endoscopic studies of the bird syrinx during phonation suggest that sound is generated by vibrating membrane folds or labia (Goller and Larsen, J. exp. Biol., 200, 2165-2176, 1997; Goller and Larsen, Proc. Natl. Acad. Sci., 4,14787-14791, 1997) and not by a whistle mechanism (Nottebohm, J. ... | Vocalization; Vibration detector; Whistle mechanism | 1998 |
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Jorgensen, Erik | Wormwholes: a commentary on K. F. Schaffner's "Genes, behavior, and developmental emergentism | Although Caenorhabditis elegans was chosen and modified to be an organism that would facilitate a reductionist program for neurogenetics, recent research has provided evidence for properties that are emergent from the neurons. While neurogenetic advances have been made using C elegans which may be u... | Organism; Neurons; Genotype | 1998 |
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Olivera, Baldomero M.; Hillyard, David R.; Gray, William Robert | ĸ-Conotoxin PVIIA is a peptide inhibiting the Shaker K+ channel | ĸ-Conotoxin PVIIA (k-PVIIA), a 27-amino acid toxin from Conus purpurascens venom that inhibits the Shaker potassium channel, was chemically synthesized in a biologically active form. The disulfide connectivity of the peptide was determined. ĸ-Conotoxin PVIIA has the following structure. | Conotoxins; k-Conotoxin PVIIA; Conus purpurascens | 1998 |
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Olivera, Baldomero M.; ; McIntosh, J. Michael | α-Conotoxin AuIB selective blocks α3ß4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release | Neuronal nicotinic acetylcholine receptors (nAChRs) with putative α3ß4-subunits have been implicated in the mediation of signaling in various systems, including ganglionic transmission peripherally and nicotine-evoked neurotransmitter release centrally. However, progress in the characterization of... | Conotoxins; a-Conotoxin AuIB; Norepinephrine release | 1998 |
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Olivera, Baldomero M.; Gray, William Robert; Hillyard, David R. | μ-Conotoxin PIIIA, a new peptide for discriminating among tetrodotoxin-sensitive Na channel subtypes | We report the characterization of a new sodium channel blocker, m-conotoxin PIIIA (m-PIIIA). The peptide has been synthesized chemically and its disulfide bridging pattern determined. | Conotoxins; m-Conotoxin PIIIA; Sodium channel blockers | 1998 |