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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
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Horch, Kenneth W. | Action potential classification with dual channel intrafascicular electrodes | Using recordings of peripheral nerve activity made with carbon fiber intrafascicular electrodes, we compared the performance of three different recording techniques (single channel, differential, and dual channel) and four different unit classification methods (linear discriminant analysis, temp... | Carbon fiber intrafascicular electrodes; Dual channel recording | 1994 |
| 2 |
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Gesteland, Raymond F.; Ives, Jeffrey T.; Stockham, Thomas G. | Automated film reader for DNA sequencing based on homomorphic deconvolution | An automated reader for electrophoresis based DNA sequencing methods is described that provides fast and accurate sequence determination. Digitized sequencing lanes are processed with homomorphic blind deconvolution in preparation for peak detection, interlane alignment, peak refinement and base cal... | Sequence Analysis; Electrophoresis; Automated Film Reader; Homomorphic Deconvolution | 1994 |
| 3 |
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Horch, Kenneth W. | Classification of action potentials in multi unit intrafascicular recordings using neural network pattern recognition techniques | Neural network pattern-recognition techniques were applied to the problem of identifying the sources of action potentials in multi-unit neural recordings made from intrafascicular electrodes implanted in cats. The network was a three-layer connectionist machine that used digitized action potenti... | Intrafascicular electrodes; Multi-unit neural activity; Artificial neural networks | 1994 |
| 4 |
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Horch, Kenneth W. | Control of ankle position using neural feedback | This paper describes a closed loop control system that uses afferent neural activity from muscle spindle fibers as feedback for controlling ankle position. The gastrocnemius muscle was stimulated through a dual channel intrafascicular electrode implanted in a fascicle of the tibial nerve. Dual cha... | Neuromuscular stimulation; Peripheral nerve; Joint angle | 1994 |
| 5 |
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Gesteland, Raymond F.; Weiss, Robert B. | Efficient shine- Dalgarno sequence but not translation is necessary for LacZ mRNA stability in Escherichia coli | The 5' ends of many bacterial transcripts are important in determining mRNA stability. A series of Shine-Dalgarno (SD) sequence changes showed that the complementarity of the SD sequence to the anti-SD sequence of 16S rRNA correlates with lacZ mRNA stability in Escherichia coli. Several initiation c... | Protein Biosynthesis; Ribosomes; Escherichia coli; Shine-Dalgarno Sequence | 1994 |
| 6 |
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Horch, Kenneth W. | Mechanical testing of metallic and polymeric intrafascicular electrodes | We are exploring alternatives to Pt/Ir wire for constructing ultra-flexible neural intrafascicular electrodes suitable for chronic implantation. In this study we measured the flexural properties of several kinds of fine metal wires and conducting polymer fibers. The fibers were made either of in... | Intrafascicular electrodes; Polymer fibers | 1994 |
| 7 |
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Gesteland, Raymond F.; Atkins, John F.; Wills, Norma M. | rRNA-mRNA base pairing stimulates a programmed -1 ribosomal frameshift | Base pairing between the 3' end of 16S rRNA and mRNA is shown to be important for the programmed -1 frameshifting utilized in decoding the Escherichia coli dnaX gene. This pairing is the same as the Shine-Dalgarno pairing used by prokaryotic ribosomes in selection of translation initiators, but for ... | Frameshifting; Escherichia coli; Binding Sites; Base Composition | 1994 |
| 8 |
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Horch, Kenneth W. | Tracking changes in action potential shapes in chronic multi-unit intrafascicular recordings using neural network pattern recognition techniques | A novel scheme is proposed to train an Artificial Neural Network (A") classifier, on a repeated basis, in order to track temporal changes in the shapes of the action potentials recorded through chronically implanted intrafascicular electrodes. This scheme uses classification results of the ANN Clas... | Intrafascicular electrodes; Artificial neural network | 1994 |
| 9 |
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Gesteland, Raymond F.; Atkins, John F.; Tuohy, Therese M. | Uninterrupted translation through putative 12-nucleotide coding gap in sequence of carA: business as usual | Previous work of others reported an untranslated stretch of 12 nucleotides in the 5' coding sequence of carA from Pseudomonas aeruginosa. However, N-terminal protein sequencing of carA-lacZ translational fusions shows that these 12 nucleotides are normally translated in a continuous triplet manner, ... | Base Sequence; Protein Biosynthesis; Sequence Deletion | 1994 |
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