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1 Ogburn, Joyce L.Acquiring minds want to know: a glimpse of paradigmsAcquiring Minds Want to Know column: "The concept of the paradigm, as generally cited in the literature, derives from the work of Thomas Kuhn in the 1960's. Kuhn, an historian of science, set out to explore how science, and scientists, actually worked. Kuhn found that scientific activity tends to be...Thomas Kuhn; Paradigms; Librarianship, trends; Librarianship, Philosophy; of1993-04
2 Thomas, Kirk R.; Capecchi, Mario R.Location of crossovers during gene targeting with insertion and replacement vectors.Gene targeting was used to introduce nonselectable genetic changes into chromosomal loci in mouse embryo-derived stem cells. The nonselectable markers were linked to a selectable marker in both insertion- and replacement-type vectors, and the transfer of the two elements to the Hprt locus was assaye...Genetic Vectors; Molecular Sequence Data; Restriction Mapping1993-04
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