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Creator | Title | Description | Subject | Date |
1 |
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Olivera, Baldomero M. | Calcium channel antagonists: ω-conotoxin defines a new high affinity site | The ω-conotoxins, a class of Ca2+ channel antagonists from fish-hunting marine snails, have recently been described (Olivera, B. M., McIntosh, J. M., Zeikus, R., Gray, W. R., Varga, J., Rivier, J., de Santos, V., and Cruz, L. J. (1985) Science, 230, 1338-1343). One of these peptide neurotoxins... | Conotoxins; Calcium channels; Synaptosomes; Neurotoxins | 1986 |
2 |
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Blair, David F. | Chemical and spectroscopic evidence for the formation of a ferryl Fea3 intermediate during turnover of cytochrome c oxidase | When partially reduced cytochrome c oxidase samples are reoxidized with dioxygen, an EPR-silent dioxygen intermediate, which is at the three-electron level of dioxygen reduction, is trapped at the dioxygen reduction site. The intermediate has novel spectral features at 580 and 537 nm. Combined op... | Cytochrome c oxidase; EPR; Fea3 intermediate; Reduction | 1986 |
3 |
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Bastiani, Michael | Guidance of neuronal growth cones in the grasshopper embryo. I. Recognition of a specific axonal pathway by the pCC neuron | The selective affinities that growth cones display for specific axonal surfaces give rise to stereotyped patterns of selective fasciculation. Previous studies on cell recognition by neuronal growth cones in the grasshopper embryo led to the proposal and initial experimental testing of the labeled-p... | Fascicle; Axon; Affinity | 1986 |
4 |
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Bastiani, Michael | Guidance of neuronal growth cones in the grasshopper embryo. II. Recognition of a specific axonal pathway by the aCC neuron | In the previous paper, we experimentally analyzed the selective affinity of the pCC growth cone for the MP1/dMP2 fascicle in the grasshopper embryo. Here we describe a similar experimental analysis demonstrating the selective affinity of the aCC growth cone for the U fascicle. These results support... | Axon; Cell; Fascicle | 1986 |
5 |
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Bastiani, Michael | Guidance of neuronal growth cones in the grasshopper embryo. III. Recognition of specific glial pathways | In the previous 2 papers, we focused on the selective affinities that growth cones display for specific axonal pathways. Little is known, however, about how this orthogonal scaffold of axonal pathways in the CNS is established in the first place, and what, if any, role glia might play in these even... | CNS; Nerve; Cells | 1986 |
6 |
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Bastiani, Michael | Guidance of neuronal growth cones in the grasshopper embryo. IV. Temporal delay experiments | In the previous 3 papers, we demonstrated that neuronal growth cones display selective affinities for both specific axonal and glial pathways in the grasshopper embryo; for example, the pCC growth cone selectively recognizes the MPl/dMP2 axons, while the aCC growth cone selectively recognizes the U... | Pathways; Neurons; Axons | 1986 |
7 |
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Capecchi, Mario R.; Thomas, Kirk R. | High frequency targeting of genes to specific sites in the mammalian genome | We corrected a defective gene residing in the chromosome of a mammalian cell by injecting into the nucleus copies of the same gene carrying a different mutation. We determined how the number, the arrangement, and the chromosomal position of the integrated gene, as well as the number of injected mo... | Homologous recombination; Mutant genes; Mammalian genome | 1986 |
8 |
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Seger, Jon | Ideas in ecology | The word "ecology" means different things to different people. For example, during the last 25 years or so the word has been used to label attitudes, life-styles, consumer goods, political parties, and college courses. In the 1960s one university renamed its "Home Economics" course "Home Ecology."... | Behavioral ecology; Population ecology | 1986 |
9 |
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Beckerle, Mary C. | Identification of a new protein localized at sites of cell-substrate adhesion | A new protein found at sites of cellsubstrate adhesion has been identified by analysis of a nonimmune rabbit serum. By indirect immunofluorescence this serum stains focal contacts (adhesion plaques) and the associated termini of actin filament bundles in cultured chicken cells. | Actin; Nonimmune rabbit serum; Polypeptide | 1986 |
10 |
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Jorgensen, Erik | Multiple transcripts from the Antennapedia gene of Drosophila melanogaster | The structures of four major transcripts from the homeotic gene Antennapedia of Drosophila melanogaster were determined. These transcripts constitute two RNA classes, each class initiating from a unique promoter but sharing 3' exons. Within the shared sequences is a major open reading frame encoding... | Mutations; Sequences ; RNA | 1986 |
11 |
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Clayton, Dale H. | Neotropical tineidae, II: biological notes and descriptions of two new moths phoretic on spiny pocket mice in Costa Rica (Lepidoptera: Tineoidea) | Two new species of tineid moths discovered riding on the backs of two species of spiny pocket mice (Heteromyidae) in Costa Rica are described. Amydria selvae, new species, was found on Heteromys desmarestianus Gray in the rainforest at Finca La Selva and Ptilopsaltis santarosae, new species, occurr... | Neotropical Tineidae; Phoretic moths; Amydria selvae; Heteromys desmarestianus; Ptilopsaltis santarosae; Liomys salvini; Mouse moths | 1986 |