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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
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O'Rourke, Dennis H. | Ascertainment bias for non-twin relatives in twin proband studies | When families are ascertained through affected twins, as for example when twin probands are selected from a registry and their non-twin relatives studied, a correction for ascertainment bias is needed. It is shown that probandwise counting (where relatives of doubly ascertained twin pairs are counte... | Genetic; Transmission; Models | 1982 |
| 2 |
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O'Rourke, Dennis H. | Refutation of the general single locus model for the etiology of schizophrenia | All published studies on the familial incidence of schizophrenia appropriate for testing the applicability of the general single-locus two-allele model are examined under the assumption of a unitary etiology for all schizophrenia. We show that the single major locus model is inadequate to predict th... | Genetics; Diseases in Twins; Chromosome Mapping | 1982 |
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