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Zhu, Judy | Analysis of the pH-dependent equilibrium relationship between the guanine oxidation products 5-guanidinohydantoin and iminoallantoin | Oxidation of 2'-deoxyguanosine (dG) results in the major two-electron product 8-oxo-7,8-dihydro-2'-deoxyguanosine (dOG) that can undergo further oxidation to other products. One such product is 5-guanidinohydantoin (dGh) that is highly mutagenic and has been found in vivo. The ring architecture of d... | Oxidation; guanine oxidation products; 5-guanidinohydantoin; iminoallantoin; equilibrium relationship | 2015-05 |
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