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Creator | Title | Description | Subject | Date |
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Warner, Homer R. | A Mathematical Approach to Medical Diagnosis: Application to Congenital Heart Disease | Biomedical Informatics | | 1992 |
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Caserta, Michael; Lund, Dale A. | Bereavement stress and coping among older adults: expectations versus the actual experience | This investigation compared the stress and coping levels of 108 older adults who recently lost their spouse with expectations of stress and coping reported by eighty-five matched nonbereaved controls. While the bereaved reported moderately high stress levels over two years, their stress scores were ... | Coping; Bereavement stress; Spousal bereavement | 1992 |
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Baehr, Wolfgang | Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter | We have previously shown that postnatal expression of the viral oncoprotein SV40 T antigen in rod photoreceptors (transgene MOT1), at a time when retinal cells have withdrawn from the mitotic cycle, leads to photoreceptor cell death (Al-Ubaidi et al., 1992. Proc. Natl. Acad. Sci. USA. 89:1194-1198).... | Simian virus 40; Retinol-Binding Proteins; Promoter Regions (Genetics) | 1992 |
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Kestle, John R. W. | Comparison between magnetic resonance imaging and computed tomography for stereotactic coordinate determination | The spatial accuracy of magnetic resonance imaging (MRI) has not been established for stereotactic surgery. Magnetic susceptibility artifacts may lead to anatomical distortion and inaccurate stereotactic MRI coordinates, especially when targets are in regions of the brain out of the center of the ma... | Computed tomography; Stereotactic coordinates; Stereotactic surgery | 1992 |
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Warner, Homer R. | Comparison of Different Information Content Models by Using Two Strategies: Development of the Best Information Algorithm for Iliad | Biomedical Informatics | | 1992 |
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Warner, Homer R. | Comparison of Different Information Content Models by Using Two Strategies: Development of the Best Information Algorithm for ILIAD | Biomedical Informatics | | 1992 |
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Capecchi, Mario R. | Creating mice with targeted disruptions in protooncogenes and homeobox genes, NIH Director's Lecture given May 21, 1992 | This is an audio transcript of a 1 hour, 2 minutes and 12 seconds lecture given at the National Institutes of Health by Mario Capecchi on 1992/05/21. Beginning with a short summary of the mechanics of gene transfer and the ability to create germline chimera with mutations that become hereditary wit... | Transgenic mice; Gene targeting; Genetic engineering; Molecular genetics; Mutagenesis; Homeobox genes; Histology - Pathological; Gene expression; Gene regulation; Genotype; Phenotype | 1992 |
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Gardner, Reed M. | Digital Electronic Communications Between ICU Ventilators and Computers and Printers | Biomedical Informatics | | 1992 |
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Warner, Homer R. | The ILIAD Program: An Expert Computer Diagnostic Program | Biomedical Informatics | | 1992 |
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Warner, Homer R. | ILIAD's Role in the Generalization of Learning Across a Medical Domain | Biomedical Informatics | | 1992 |
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Warner, Homer R. | ILIAD's Role in the Generaliztion of Learning Across a Medical Domain | Biomedical Informatics | | 1992 |
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Baehr, Wolfgang | In vitro isoprenylation and membrane association of mouse rod photoreceptor cGMP phosphodiesterase alpha and beta subunits expressed in bacteria | We investigated the specificity of CAAX box-related isoprenylation of rod photoreceptor cGMP phosphodiesterase (PDE) subunits expressed in bacteria and the consequences of this modification on rod disk membrane association. Full-length cDNA sequences of the alpha and beta subunits of mouse PDE, inse... | Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data | 1992 |
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Gardner, Reed M. | Integration of a Stand-Alone Expert System with a Hospital Information System | Biomedical Informatics | | 1992 |
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Couldwell, William T. | Malignant glioma-derived soluble factors regulate proliferation of normal adult human astrocytes | Malignant gliomas are characteristically surrounded by marked gliosis. To assess whether glioma-derived products contribute to the proliferation of astrocytes, a feature of the gliosis response, we evaluated the influence of culture supernatants from malignant human glioma lines and tumor cyst fluid... | Astrocyte; Glioma; Gliosis; Proliferation; Soluble factors | 1992 |
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Warner, Homer R. | Medical Informatics: Application of Computers to Medical Science | Biomedical Informatics | | 1992 |
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Normann, Richard A.; Horch, Kenneth W.; Cha, Kichul | Mobility performance with a pixelized vision system | A visual prosthesis, based on electrical stimulation of the visual cortex, has been suggested as a means for partially restoring functional vision in the blind. The prosthesis would create a pixelized visual sense consisting of punctate spots of light (phosphenes). The present study investigated the... | Visual Prosthesis; Mobility; Phosphene Simulator | 1992 |
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Florsheim, Paul W. | Mourning the loss of "self as father": a longitudinal study of fatherhood among the druze | IT is within the context of the parent-child relationship - through the processes of attachment, loss, separation and individuation - that we grow and develop interpersonally and intrapsychically (Bowlby 1969, 1980; Mahler et al. 1975; Pollock, 1989). Most developmentalists agree that changes in th... | | 1992 |
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Caserta, Michael; Lund, Dale A. | Older bereaved spouses' participation in self-help groups | This study reports on bereaved spouses' assessments of their participation in twenty-six self-help groups which consisted of eight weekly meetings (short-term; N = 82) or ten monthly meetings in addition to the weekly ones (long-term; N = 52). Regardless of the duration of the groups whether they w... | Older bereaved spouses | 1992 |
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Warner, Homer R. | Performance of a Diagnostic System (ILIAD) as a Tool for Qualilty Assurance | Biomedical Informatics | | 1992 |
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Baehr, Wolfgang | Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel | We have determined the primary structures of the human and mouse retinal rod cGMP-gated cation channel by analysis of cDNA clones and amplified DNA. The open reading frames predicted polypeptides of 690 and 683 residues exhibiting 88% sequence similarity. Sequence comparison indicated that the rod c... | Restriction Mapping; Sequence Homology, Nucleic Acid; Chromosomes, Human, Pair 4 | 1992 |
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Couldwell, William T. | Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II. Effects of glioma mitogens and modulators of protein kinase C | THE PROLIFERATION RATES of gliomas may be modulated by the protein kinase C (PKC) signal transduction system. The present study was undertaken to further examine the role of PKC system in growth regulation of gliomas in vitro by measurement of PKC activity over various phases of tumor growth and by ... | Protein kinase C; Brain neoplasms; Growth factor; Glioma; Phorbol ester | 1992 |
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Normann, Richard A.; Abbasi, Masoud; Johansson,Torbjorn | Silicon carbide enhanced thermomigration | The widespread acceptance of thermomigration technology to produce through-chip interconnects has been impaired by (i) a random walk of the Si-Al liquid eutectic inclusion as it traverses the wafer, and (ii) a ?surface barrier? which allows thermomigration of only relatively large inclusions. In ... | Silicon Dioxide; Thermometers; Transducers; Thermomigration Technology; Infrared Lamps | 1992 |
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Normann, Richard A.; Johansson,Torbjorn; Abbasi, Masoud; Huber, Robert J. | Three-dimensional architecture for a parallel processing photosensing array | A three-dimensional architecture for a photosensing array has been developed. This silicon based architecture consists of a 10 x 10 array of photosensors with 80 microns diameter, through chip interconnects to the back side of a 500 microns thick silicon wafer. Each photosensor consists of a 300 x 3... | Retina; Optics; Silicon; Photosensing | 1992 |