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 | Zurbuchen, Rudi | Macrocyclization of glucagon-like peptide (GLP-1) by thiol-ene reaction | Macrocyclization of peptides helps maintain a stable alpha helical structure using a conformational constraining staple. One such peptide, glucagon-like peptide-1 (GLP-1), is a 37 amino acid peptide agonist for the GLP-1 receptor and has the ability to lower blood glucose levels and is responsible ... | Peptide hormones - Receptors - Research; Ring formation (Chemistry) - Research; Macrocyndization; GLP-1; Swim kinematics; Pre-pulse inhibition | 2016-05 |