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Creator | Title | Description | Subject | Date |
126 |
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Astin, Holly M. | Modulating Intestinal Liver X Receptor Activity to Alter the Development of Atherosclerosis in Zebrafish | | | 2016 |
127 |
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Astin, M. Holly | Modulating Intestinal Liver X Receptor Activity to Alter the Development of Atherosclerosis in Zebrafish | The liver X receptors (LXRs) are important regulators of lipid and cholesterol metabolism and control diverse pathways in development, reproduction, metabolism, immunity and inflammation. Thus, LXRs have potential as therapeutic targets for diseases as diverse as lipid disorders, atherosclerosis... | Liver X receptors - Research; Zebrafish - genetics | 2016-08 |
128 |
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Rou, Janvida | Monte-Carlo simulation of stellar intensity interferometry | Stellar intensity interferometers will allow for achieving stellar imaging with a tenth of a milli-arcsecond resolution in the optical band by taking advantage of the large light collecting area and broad range of inter-telescope distances offered by future gamma-ray Air Cherenkov Telescope (ACT) ar... | Monte Carlo simulation | 2012-05 |
129 |
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Scholl, Wallis | Nanomite-Decorated Nanoparticles as Surface-Enhanced Spectroscopy Substrated | Surface-enhanced spectroscopy substrates utilize the localized surface plasmon resonance of nanoparticles for optical, photocatalysis, and biological and chemical sensing applications. Plasmonic anisotropic nanoparticles with sharp tips focus the electromagnetic field of the localized surface plasmo... | | 2020 |
130 |
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Bernardo, Madeline F. | The Neural Mechanisms of Sexual Transformation in Thalassoma Bifasciatum, the Bluehead Wrasse | Thalassoma bifasciatum, the bluehead wrasse, is a protogynous sequential hermaphrodite and a commonly used model for studying environmental sex determination and adult sexual plasticity. Terminal phase (TP) male bluehead wrasses demonstrate characteristic behaviors and coloration changes when courti... | | 2020 |
131 |
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Kroll, Tyler | Numerical floating-point code: precision-independence, base-independence, and other programming considerations | The knowledge and skills of the floating-point-literate mathematician are seldom lauded, though central to the art of translating the world of mathematics into the language of computers. This thesis highlights the importance of floatingpoint literacy through various high-utility techniques relevant ... | | 2020 |
132 |
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Halberg, Charles | On causality in machine learning | Although the studies of causal inference and machine learning arose independently, there are emerging intersections which are proving fruitful for both fields. One of the major modern challenges in AI is to develop robust, generalizable models which can perform across a number of different tasks wit... | | 2022 |
133 |
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Copinga, Aidan | Optimal transport and applications in partial differential equations | In the 18th century, Gaspard Monge created a mathematical framework to find the best way to describe the optimal way to rearrange the dirt dug out from the land into castle walls or other desired shapes. More recently, in the 20th century, Leonid Kantorovich explored infinite dimensional optimizatio... | | 2022 |
134 |
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Fullmer, Alexander T. | Optimization of gamma/hadron separation under variable source intensities and energy spectra | The High Altitude Water Cherenkov (HAWC) gamma-ray observatory consists of an array of water Cherenkov tanks that can detect extensive air showers (EAS) generated by astrophysical cosmic rays and gamma rays. One of the greatest challenges in using the HAWC observatory to search for astrophysical gam... | Gamma ra sources - Observations; Cosmic rays - Observations; Gamma ray astronomy - Research | 2014-05 |
135 |
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Cowley, Jacob | Optimization of total synthesis of indolizidine alkaloids VIA nickel catalyzed (4 + 2) cyclization utilizing silyl and stannyl alkynes | In order to expand the versatility of the synthetic route to naturally occurring indolizidine alkaloids previously developed in the Louie Group, a path was developed using a bicyclic azetidinone to produce indolizidine alkaloids such as (+)-seco-antofine. However, due to the asymmetric nature of the... | | 2021 |
136 |
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Alexander, Amanda | Parental conflict with adult children | Parental conflict with adult children is something that is well known anecdotally, but has rarely been studied in light of other, more serious conflicts between parents and their children. However, parental conflict with adult children (adult being defined as between the ages of 18 and 25) is someth... | Adult children - Family relationships; Adult children - Psychology | 2012-05 |
137 |
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Watson, Andre | Patterns of parasitism in a common Utah Rodent | Male-biased parasitism, where males are more commonly infected with and have higher parasite loads, is common across vertebrate taxa. Several factors could be driving this pattern. The immunocompetence handicap hypothesis suggests that higher testosterone levels in males suppress immune function whi... | | 2022 |
138 |
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Fox, Zach | The physical effects of solvent in molecule-based magnets | Molecule-based magnets are being studied in order to expand the utility of magnets in modern devices. Advantages of molecule-based magnets include less energy intensive synthesis and greater versatility through changes to organic components of the structure. This class of materials is studied to ena... | Magnets - Experiments | 2012-05 |
139 |
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Hales, Laurel | Physics show and tell and elementary science education | It is a well-known fact that American children are performing below their peers in international science and mathematics examinations, leading to what is commonly called the STEM education crisis. This project was created in an attempt to resolve this crisis by improving elementary school science ed... | Science - Study and teaching (Elementary) - United States | 2014-05 |
140 |
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Radhakrishnan, Parvathi | PI3K inhibitors as potential new therapy against breast cancer progression | Receptor tyrosine kinases (RTKs) and their pleiotropic effectors play key roles in metastasis. Met and Ron are RTKs that have been shown to contribute to tumor growth and metastasis in both animal models and in patients. Recently, an alternative Ron isoform known as "short-form" Ron (sfRon) was asso... | Breast - Cancer - Treatment - Research; Protein - tyrosine kinase - inhibitors - Therapeutic use; Enzyme inhibitors - Therapeutic use. - Research; Biology - Research | 2014-05 |
141 |
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Lee, Hani | Post-traumatic headache: an opportunity to develop new preclinical models for better understanding of pathology and treatment | Post-traumatic headache (PTH) is identified as one of the most frequent symptoms following traumatic brain injury (TBI) (Faux & Sheedy, 2008). Despite the high prevalence, there are currently no treatments which specifically target PTH. Instead of etiology-specific treatments, individuals suffering ... | | 2022 |
142 |
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Peterson, John | Potential Therapeutic Inhibition of Epigenetic Modulator LSDI in Glioblastoma Multiforme | Glioblastoma (GBM) is the most common primary brain tumor in adults, and while advances in surgery, radiation, and standard chemotherapies have improved survival in this disease marginally over the years, the outcomes for most patients remain disappointing (Bhat, 2013). Recent studies have identifie... | | |
143 |
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Trakhimets, Alesia | Pre-clinical trials of anti-neoplastic drugs using zebrafish with T-cell cancer | Note: To agree with NCBI nomenclature guidelines, human gene abbreviations are italicized and capitalized; human protein abbreviations are non-italicized and capitalized, and zebrafish gene abbreviations are italicized in lowercase. T lymphocytes, or T-cells, are blood cells that normally fight vira... | Antineoplastic agents - Testing; Zebra danio | 2013-04 |
144 |
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Christensen, Kiana | Quantifying Patterns of Squamate Dental Complexity | Squamate reptiles are ideal subjects for investigating relationships between diet and dentition patterns because they exhibit wide dietary diversity and taxonomic abundance. Most previous research is qualitative and limited to a basic assessment of the influence diet has on dentition (Hotton, 1955; ... | | 2020 |
145 |
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Tuft, Marie | Quantitative analysis of virus trafficking in a biological cell | Virus replication is a complex process that is important to understand. If a virus is to successfully infect a host cell it must travel from the cell wall to the nucleus by hijacking that cell's existing transport system of microtubules. This motion occurs as two iterated steps: passive diffusion th... | Viruses -- Reproduction -- Mathematical models; Virus trafficking | 2015-05 |
146 |
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Dutson, Matthew J. | Reconstruction of Cosmic Ray Geometry using Cherenkov backscattering | Fluorescence detectors are often used to examine the energy spectrum and arrival directions of ultra high energy cosmic rays. An accurate reconstruction of geometry is key when determining both energy and direction. In the past, it has been necessary to build multiple fluorescence detectors to take ... | | 2017 |
147 |
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Bingham, Kouver | Reflection groups and coxeter groups | In this paper we give a survey of the theory of Coxeter Groups and Reflection groups. This survey will give an undergraduate reader a full picture of Coxeter Group theory, and will lean slightly heavily on the side of showing examples, although the course of discussion will be based on theory. We'll... | Finite groups | 2014-07 |
148 |
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Ellis, James H. | Refractory status epilepticus and chronic kidney disease in a large pedigree due to a variant in the mitochondrial encoded trna phenylalanine (MT-TF) gene | Mitochondrial disorders present with a wide spectrum of neurological manifestations. Clinical syndromes are described largely by phenotypic indicators. Epilepsy is a common but not universal feature. Myoclonus epilepsy with ragged red fibers (MERRF) is a common clinical syndrome that presents with e... | | 2018 |
149 |
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Steiner, William | Regulation of protein complexes during hedgehog signal transduction | The Hedgehog (Hh) pathway is an evolutionarily conserved signaling pathway essential in embryonic development and tissue homeostasis. Several cancers can form as a result of Hh pathway dysfunction. The G protein-coupled receptor (GPCR) Smoothened (SMO) is activated upon binding of the secreted Hh pr... | | 2021 |
150 |
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Bader, Cecily | The Response of Arabidopsis Mutant BPS1-2 on Salt Media | How would our world change if salt tolerance could be engineered in plants? The Arabidopsis mutant bps1-2 has been shown to respond differently on salt media than a nonmutated plant would. In normal conditions, the bps1-2 mutant will arrest development in the root and shoot shortly after germination... | | 2017 |