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1 Hinchman, Colin4D flow characteristics of left atrial blood flow after atrial fibrillationAtrial fibrillation is the most prevalent cardiac arrhythmia and causes increased risk for stroke, yet accurate pathophysiological diagnosis remains a challenge. This study aimed to further investigate the physiologic biomarkers in the left atrium (LA) related to atrial fibrillation (AF) using 4D fl...2019
2 Temme, JackA closer look at aberrant muscle functionWhen a skeletal muscle is inhibited from operating at its full function it is called an aberrant muscle. Such inhibition tends to occur after joint trauma in order to protect the injured area from further aggravation. However, inhibition can linger after the injury is healed, which negatively impact...2021
3 German, MassiellA genetic analysis of VSX2 function in the mouse eyeVsx2 is a homeodomain-containing transcription factor essential for maintenance of neuroretinal identity and neurogenesis. Vsx2 is believed to function via mechanisms that are strictly cell-intrinsic. However, recent research reveals evidence for involvement of Vsx2-mediated cell non-autonomous mech...Neurogenesis - physiology2012-05
4 Sperber, Alexander M.A novel approach to differentiating cardiac fibroblasts from induced pluripotent stem cellsHeart disease remains the leading cause of death in the United States, and such disease is caused by electrical, chemical, or biomechanical imbalances in the heart. The two most abundant cells comprising the heart that are responsible for these functions are cardiomyocytes and cardiac fibroblasts. I...2022
5 Shapiro, DarienActivation of transient receptor potential ankyrin-1 by wood smoke particulate materialExposure to wood smoke particulate matter (WSPM) has been linked to exacerbation of pre-existing respiratory conditions such as asthma, development of chronic obstructive pulmonary disease (COPD), and premature deaths. While it is clear that WSPM exposure is hazardous to human health, the molecular ...Smoke; Physiological effect2012-05
6 Calder, DallenAdipocyte enhancer binding protein 1 (AEBP1) as a potential therapeutic target to combat cardiac fibrosisFibrosis is one of the major hallmarks of heart failure (HF) progression and is characterized by fibroblast activation and excess extracellular matrix (EMC) deposition. RNA sequencing of myocardial tissue acquired from HF patients showed a significant upregulation of adipocyte enhancer binding prote...2022
7 Isom, AnikaAmniotic fluid treatment of vocal fold injury in an in vivo rabbit modelHyaluronic acid (HA) injectables are a standard treatment for vocal fold injuries in both clinical and research settings. Results from these treatments are not permanent, however, and may vary in effectiveness. Because of this, there is a significant clinical interest in finding an alternative for H...Vocal folds; rheology; wound healing of vocal folds; hyaluronic acid; amniotic fluid; regenerative medicine2022
8 Luong, KatieAn examination of the relationship between positive covid-19 infection and vaccine hesitancy within the Utah recover study populationVaccine hesitancy is defined by the World Health Organization as a "delay in acceptance or refusal of vaccines despite availability of vaccination services," and is affected by a wide range of factors. Some of these factors identified in the literature include perceived safety and importance of vacc...COVID-19; health2023
9 Brown, AudreyAnalyzing response patterns of olfactory bulb glomeruli at low odorant concentration regimesSensory input to the olfactory system begins with the binding of an odorant molecule to an olfactory receptor (OR) contained on the surface of an olfactory sensory neuron (OSN). Olfactory bulb (OB) glomeruli receive information from OSNs containing the same OR type and are thought to help process se...2021
10 Kober, DerekAnthropogenic Climate Change and Pollen Trends: Analyzing genera-specific impacts and correlations with temperature and precipitation across the United States (1990-2018)Studies have shown that human-driven climate change is associated with both higher airborne pollen concentrations and extended allergy seasons. Research particularly indicates that the concentration of pollen is positively correlated to increasing temperatures. This study aims to analyze the pollen ...2023
11 Rohaj, AarushiApoptosis efficiency of the transfected elephant and human P35 vectors in P53 varying leiomyosarcoma cellsComparative Oncology is an approach that integrates and connects commonly occurring cancers seen in animals, into studies focused on cancer biology, prevention, and treatment in humans. Studies show that natural mechanisms can suppress cancer 1,000 times more adequately in certain animals than in hu...Doxorubicin; vectors2021
12 Mallender, ZacharyAssay of the dreem device on sleep metrics and an exploration of sleep staging in chronic short sleepers during time in bed extensionDespite clear and plentiful research that sleeping less than seven hours per night has a wide array of health consequences, a large portion of American adults report sleeping less than seven hours per night and thus receive chronic insufficient sleep. Many studies exploring the consequences of insuf...2022
13 Estrada, JohannaBCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Philadelphia cromosome-positive leukemiaCML 1s caused by a random reciprocal translocation that joins the ABL1 gene on chromosome 9, with the BCR gene on chromosome 22. The result is the formation of the oncogenic BCR-ABL1 gene. This derivative chromosome is widely known as the Philadelphia Chromosome (Ph+), and it encodes a deregulated, ...Leukemia -- Genetic aspects -- Research Leukemia -- Treatment -- Research2014-04
14 Ganesh, KajalBeyond the neural circuits: examining women's metal health in India alongside the complex manifestation of OCD and anxiety in miceMental health literacy (MHL) is a critical concept that refers to the recognition, mitigation, and prevention of mental health disorders. Increased MHL is achievable through funding research on the brain and mental health disorders, aiming to normalize patient struggles, provide clear explanations f...2024
15 Tazehabadi, TaraBioinformatics to detect functional interactions important for the DNA repair enzyme mutyhDNA is the blueprint of all biological life as it provides the means necessary for sharing of genetic information. DNA is formed and stabilized by interactions between four unique bases, Adenine (A), Cytosine (C), Guanine (G), and Thymine (T) which come together in predetermined patterns to create a...2022
16 Beseris, EthanBiological impact protection in human facial hairOur study investigated selective mechanisms that influenced the evolution of facial hair in human males (Homo sapiens). Beards are often perceived as an indicator of masculinity and social dominance in men, suggesting that they may play a role in male contest competition. Some authors propose that t...2018
17 Furrer, SummerCellular and subcellular localization patterns of hepatitis delta virus in sjogren's syndrome salivary gland tissuePrimary Sjogren's syndrome (pSS) is an autoimmune disorder, predominantly affecting women, that causes dry eyes, dry mouth, fatigue, and other extraglandular manifestations (Le Goff et al., 2017). It has been shown that chronic pathogen exposure can lead to development of autoimmune diseases such as...2022
18 Thomas, NikitaCellular ultrastructure of C. elegans nervous systemDetermining the ultrastructural organization of the nervous system is a key step in understanding how complex behavior is generated. For a nervous system to function, it must be wired accurately. A complete wiring diagram, referred to as a connectome, can be created by tracing neuronal profiles thro...Caenorhabditis elegans - Nervous system2013-05
19 Andersen, KaraCervical dorsal root ganglion imaging for studying neuronal nocicieptive ciruit changes in migranine modelsMigraine neuroscience is a field in its infancy, with migraine being a remarkably common yet poorly understood sensory circuit disorder. It is characterized by attacks of unilateral, throbbing craniofacial pain, with sensitivity to movement, visual, auditory, and other afferent inputs. Migraines can...2022
20 Larson, BrookeChacterization of signaling to the degradative pathways of the cellProtein degradation in cells is a complex network of pathways that are distinct from each other but highly interconnected. Understanding how proteins are degraded in cells is important for understanding and developing treatments for diseases such as lysosomal storage diseases and neurodegenerative d...2023
21 Jensen, MadelineChanges in microbial diversity in storm-water green infrastructureIncreased urbanization has led to excess nutrients in urban ecosystems. Stormwater Green Infrastructure (SGI) is a method to capture these nutrients and prevent runoff. However, an increased understanding of ecosystem processes is needed to create more efficient SGIs. Past studies have shown that pl...2022
22 Barbeau, WilliamCharacterization of a New Ribosome Associated Quality Control PathwayProteins are life's double edged sword. Proteins are essential macromolecules of life, and the tasks that some proteins accomplish are quite marvelous. At the same time, if proteins misfold they have the potential to kill the cell that harbors them. It is becoming increasingly clear that proteins ha...Ribosomes - Research2016-12
23 Bell, MarisaCharacterization of Polyphenols in I. UmbelliferaSecondary metabolites in plants, including polyphenolics, may be responsible, in part, for diversity in the tropics. Variation in chemical defense among species of trees encourages specificity in herbivorous insects. Due to the short lifespan of insects compared to trees, diversity in chemical defen...2018
24 Little, Nancy AnnCharacterizing and mapping l(3)7E103 a gene required for Drosophila dorsal closureDorsal closure in the fruit fly Drosophila melanogaster is a complex morphogenetic process dependent upon three embryonic tissues: the lateral epidermis, leading edge epidermis, and amnioserosa. Additionally, the Jun N-terminal Kinase (JNK) and Decapentaplegic (Dpp) signaling cascades are required f...Drosophila melanogaster - Genetics; Drosophila melanogaster - Embryology2013-05
25 Richards, JacksonChasing channels: Progress in calcium channel localization in the C. Elegans synapseCalcium channels play a crucial role in neurotransmission by facilitating the flow of calcium ions necessary for synaptic vesicle fusion and neurotransmitter release. Different types of calcium channels participate in this process in the neurons of the nematode C. elegans. L- and N-type channels res...Calcium channels; Synaptic vesicles; Caenorhabditis elegans2013-05
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