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Creator | Title | Description | Subject | Date |
| 26 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 7: intractable low-back pain without stenosis or spondylolisthesis | Standards. Lumbar fusion is recommended as a treatment for carefully selected patients with disabling lowback pain due to one- or two-level degenerative disease without stenosis or spondylolisthesis. Guidelines. There is insufficient evidence available to support a treatment guideline. Options. An... | Fusion; Lumbar spine; Degenerative disease; Low back pain | 2005 |
| 27 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 8: lumbar fusion for disc herniation and radiculopathy | Standards. There is insufficient evidence to recommend a treatment standard. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. 1) Lumbar spinal fusion is not recommended as routine treatment following primary disc excision in patients with a herniated lumbar... | Fusion; Lumbar spine; Degenerative disease; Lumbar fusion; Disc herniation; Radiculopathy | 2005 |
| 28 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 9: fusion in patients with stenosis and spondylolisthesis | Guidelines. The performance of a lumbar PLF is recommended for patients with lumbar stenosis and associated degenerative spondylolisthesis who require decompression. There is insufficient evidence to recommend a treatment guideline. Options. Pedicle screw fixation as an adjunct to lumbar PLF should ... | Fusion; Lumbar spine; Degenerative disease; Lumbar fusion | 2005 |
| 29 |
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Couldwell, William T. | Harvey cushing and oskar hirsch: early forefathers of modern transsphenoidal surgery | The transnasal transsphenoidal approach is the preferred route for removal of most lesions of the sella turcica. The concept of transnasal surgery traversing the sphenoid sinus to reach the sella has existed for nearly a century. A comprehensive historical overview of the evolution of transsphenoida... | | 2005 |
| 30 |
 |
Kestle, John R. W. | High incidence of tumor dissemination in myxopapillary ependymoma in pediatric patients | P Myxopapillary ependymomas (MPEs) have historically been thought to be benign tumors occurring most frequently in adults. Only 8 to 20% of these tumors occur in the first two decades of life, making this tumor a rarity in pediatric neurosurgery. Five patients with intraspinal MPEs were treated by t... | Myxopapillary ependymoma; Tumor dissemination | 2005 |
| 31 |
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Gardner, Reed M. | The International Partnership for Health Informatics Education: Lessons Learned from Six Years of Experience | Biomedical Informatics | | 2005 |
| 32 |
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Zhang, Kang | Loss of ER retention and sequestration of the wild-type ELOVL4 by Stargardt disease dominant negative mutants | PURPOSE: Mutations in ELOVL4, a member of the fatty acid elongase (ELO) family, are responsible for autosomal dominant Stargardt-like macular degeneration. The specific role of ELOVL4 in photoreceptors and the degenerative events induced by dominant ELOVL4 mutations are not well understood. As a fir... | Macular Degeneration; Transcription Factor CHOP; Molecular Chaperones | 2005 |
| 33 |
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Baehr, Wolfgang | Metabolism and transactivation activity of 13,14-dihydroretinoic acid | The metabolism of vitamin A is a highly regulated process that generates essential mediators involved in the development, cellular differentiation, immunity, and vision of vertebrates. Retinol saturase converts all-trans-retinol to all-trans-13,14-dihydroretinol (Moise, A. R., Kuksa, V., Imanishi, Y... | Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Retinoid X Receptors | 2005 |
| 34 |
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Kestle, John R. W. | Multicenter prospective cohort study of the Strata valve for the management of hydrocephalus in pediatric patients | Object. Previous reports suggest that adjustable valves may improve the survival of cerebrospinal fluid shunts or relieve shunt-related symptoms. To evaluate these claims, the authors conducted a prospective multicenter cohort study of children who underwent placement of Strata valves. Methods. Pat... | Ventriculoperitoneal shunt; Strata valve; Adjustable valves; Pediatric neurosurgery | 2005 |
| 35 |
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Baehr, Wolfgang | Novel GCAP1 missense mutation (L151F) in a large family with autosomal dominant cone-rod dystrophy (adCORD) | PURPOSE: To elucidate the phenotypic and biochemical characteristics of a novel mutation associated with autosomal dominant cone-rod dystrophy (adCORD). METHODS: Twenty-three family members of a CORD pedigree underwent clinical examinations, including visual acuity tests, standardized full-field ERG... | Polymorphism, Single-Stranded Conformational; Guanylate Cyclase-Activating Proteins; DNA Mutational Analysis | 2005 |
| 36 |
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Couldwell, William T. | Personal perspective: AANS Bulletin's momentum continues: new editor considers peer review, practice survey impact | With this issue, I assume the reins as editor of the AANS Bulletin. I am indebted to James Bean, MD, for his extraordinary efforts in this capacity, as witnessed by review of the recent issues published under his leadership. An important initiative put forth by Dr. Bean and the Bulletin Advisory Boa... | | 2005 |
| 37 |
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Baehr, Wolfgang | Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis | BACKGROUND: Leber congenital amaurosis (LCA), a heterogeneous early-onset retinal dystrophy, accounts for approximately 15% of inherited congenital blindness. One cause of LCA is loss of the enzyme lecithin:retinol acyl transferase (LRAT), which is required for regeneration of the visual photopigmen... | Disease Models, Animal; Genetic Vectors; Molecular Sequence Data | 2005 |
| 38 |
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Kestle, John R. W. | Potentially useful outcome measures for clinical research in pediatric neurosurgery | The choice of outcome (or outcomes) and their measurement are critical for a sound clinical trial. Surgeons have traditionally measured simple outcomes such as death, duration of survival, or tumor recurrence but have recently developed more sophisticated measures of the effect of an intervention. M... | Pediatric neurosurgery | 2005 |
| 39 |
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Couldwell, William T. | Rathke cleft cyst intracystic nodule: a characteristic magnetic resonance imaging finding | Object. The fluid content of Rathke cleft cysts (RCCs) displays variable appearances on magnetic resonance (MR) images and can appear indistinguishable from other intrasellar or suprasellar cystic lesions. Intracystic nodules associated with individual RCCs have been noted, but to date their signifi... | | 2005 |
| 40 |
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Baehr, Wolfgang | Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT) | Lecithin:retinol acyltransferase (LRAT) is believed to be the predominant if not the sole enzyme in the body responsible for the physiologic esterification of retinol. We have studied Lrat-deficient (Lrat-/-) mice to gain a better understanding of how these mice take up and store dietary retinoids a... | Chromatography, High Pressure Liquid; Mice, Transgenic; Tissue Distribution | 2005 |
| 41 |
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Baehr, Wolfgang | Role of photoreceptor-specific retinol dehyrogenase (prRDH) in the retinoid cycle in vivo | The retinoid cycle is a recycling system that replenishes the 11-cis-retinal chromophore of rhodopsin and cone pigments. Photoreceptor-specific retinol dehydrogenase (prRDH) catalyzes reduction of all-trans-retinal to all-trans-retinol and is thought to be a key enzyme in the retinoid cycle. We d... | Rhodopsin, Photoreceptors; prRDH (RDH8); All-trans-RDH; A2E; Retinoid cycle; Dark adaptation | 2005 |
| 42 |
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Normann, Richard A. | Statistical encoding model for a primary motor cortical brain-computer interface | A number of studies of the motor system suggest that the majority of primary motor cortical neurons represent simple movement-related kinematic and dynamic quantities in their time-varying activity patterns. An example of such an encoding relationship is the cosine tuning of firing rate with respect... | Discrete Distribution; LN Model; Neural Decoding; Neuroprosthetics; Sequential Monte-Carlo Filter | 2005 |
| 43 |
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Schmidt, Meic H. | Surgical technique and results of endoscopic anterior spinal canal decompression | Object. Decompression of the spinal canal in the management of thoracolumbar trauma is controversial, but many authors have advocated decompression in patients with severe canal compromise and neurological deficits. Anterior decompression, corpectomy, and fusion have been shown to be more reliable f... | Anterior approach; Anterior decompression; Spinal trauma; Endoscopy | 2005 |
| 44 |
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Schmidt, Meic H. | Thoracoscopic spine surgery for decompression and stabilization of the anterolateral thoracolumbar spine | The anterior thoracolumbar spine can be exposed via a variety of approaches. Historically, open anterolateral or posterolateral approaches have been used to gain access to the anterior thoracolumbar spinal column. Although the exposure is excellent, open approaches are associated with significant pa... | Endoscopic spinal surgery; Thoracic spine; Lumbar spine; Thoracoscopic spinal instrumentation | 2005 |
| 45 |
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Couldwell, William T. | Thrombosed basilar apex aneurysm presenting as a third ventricular mass and hydrocephalus | Aneurysms presenting as third ventricular masses are uncommon; most are giant aneurysms arising from the basilar apex. We present a case of a thrombosed basilar apex aneurysm presenting as a third ventricular mass and hydrocephalus in a 55-year-old man. The case is unique in the literature as the an... | Basilar apex aneurysm; Ventricular mass; Third ventriculostomy | 2005 |
| 46 |
 |
Schmidt, Meic H. | Titanium cage-assisted polymethylmethacrylate reconstruction for cervical spinal metastasis | Reconstruction and stabilization of the cervical spine after vertebrectomy is an important goal in the surgical management of spinal metastasis. The authors describe their reconstruction technique using a titanium cage-Silastic tube construct injected with polymethylmethacrylate (PMMA) augmented by... | Titanium cage; Cervical spine; Cervical spinal metastasis; Reconstruction; Vertebrectomy; PMMA reconstruction; Silastic tube | 2005 |
| 47 |
 |
Gesteland, Raymond F.; Baranov, Pavel V.; Atkins, John F.; Hammer, Andrew W. | Transcriptional slippage in bacteria: distribution in sequenced genomes and utilization in IS element gene expression | ABSTRACT: Background: Transcription slippage occurs on certain patterns of repeat mononucleotides, resulting in synthesis of a heterogeneous population of mRNAs. Individual mRNA molecules within this population differ in the number of nucleotides they contain that are not specified by the templat... | Transcription slippage; Bacterial genomes; IS element genes | 2005 |
