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Creator | Title | Description | Subject | Date |
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Schmidt, Meic H.; Apfelbaum, Ronald I. | Atlantoaxial transarticular screw fixation: a review of surgical indications, fusion rate, complications, and lessons learned in 191 adult patients | Object. In this, the first of two articles regarding C1-2 transarticular screw fixation, the authors assessed the rate of fusion, surgery-related complications, and lessons learned after C1-2 transarticular screw fixation in an adult patient series. Methods. The authors retrospectively reviewed 191 ... | Atlantoaxial junction; Craniocervical junction; Instability; Transarticular screw fixation; Fusion | 2005 |
| 2 |
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Baehr, Wolfgang; Katz, Bradley J.; Creel, Donnell J.; Zhang, Kang | Autosomal dominant cone dystrophy caused by a novel mutation in the GCAP1 gene (GUCA1A) | PURPOSE: To describe the clinical features and genetic analysis of a family with an autosomal dominant cone dystrophy (adCD). METHODS: Selected members of a family with an autosomal dominant cone dystrophy underwent ophthalmic evaluation. Blood samples were obtained, genomic DNA was isolated, and ge... | Mutation, Missense; DNA Mutational Analysis; Electroretinography | 2005 |
| 3 |
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Bernstein, Paul S.; Zabriskie, Norman A.; Zhang, Kang | CFH Y402H Confers similar risk of soft Drusen and both forms of advanced AMD | BACKGROUND: Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in the developed world. The two forms of advanced AMD, geographic atrophy and neovascular AMD, represent different pathological processes in the macula that lead to loss of central vision. S... | | 2005 |
| 4 |
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Kestle, John R. W.; Brockmeyer, Douglas Lee | Cranial base strategies for resection of craniopharyngioma in children | The optimal treatment of craniopharyngioma in children remains a challenge. The use of complete excision to minimize recurrence continues to be controversial because of the risk of postoperative morbidity and death. Advances in skull base approaches, modern microsurgical techniques, neuroimaging, an... | Craniopharyngioma; Surgical approach; Skull base surgery | 2005 |
| 5 |
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Couldwell, William T.; House, Paul A. | De novo fenestration of the optic nerve | Fenestration of the optic nerve or chiasm due to the presence of an aneurysmal dilation of the internal carotid artery (ICA) has been described previously. In three of five cases reviewed recently, the optic nerve was penetrated by an ICA?ophthalmic artery aneurysm.3 Penetration of the optic nerve w... | Fenestration; Aneurysm | 2005 |
| 6 |
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Baehr, Wolfgang | Evaluation of the 17 kda prenyl binding protein as a regulatory protein for phototransduction in retinal photoreceptors | The mammalian rod photoreceptor phosphodiesterase (PDE6) holoenzyme is isolated in both a membrane-associated and a soluble form. Membrane binding is a consequence of prenylation of PDE6 catalytic subunits, whereas soluble PDE6 is purified with a 17-kDa prenyl-binding protein (PDEdelta) tightly boun... | Amino Acid Sequence; Immunohistochemistry; Phosphoric Diester Hydrolases | 2005 |
| 7 |
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Gesteland, Raymond F.; Baranov, Pavel V.; Atkins, John F. | Expression levels influence ribosomal frameshifting at the tandem rare arginine codons AGG_AGG and AGA_AGA in Escherichia coli | ABSTRACT: The rare codons AGG and AGA comprise 2% and 4%, respectively, of the arginine codons of Escherichia coli K-12, and their cognate tRNAs are sparse. At tandem occurrences of either rare codon, the paucity of cognate aminoacyl tRNAs for the second codon of the pair facilitates peptidyl-tRNA... | Gene expression; Frameshifting; E. coli; Arginine codons | 2005 |
| 8 |
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Couldwell, William T. | False-negative magnetic resonance angiography with extracranial internal carotid artery stenosis: a report of two cases and review of the literature | Magnetic resonance angiography (MRA) is increasingly used as a noninvasive means to assess internal carotid artery (ICA) stenosis. When used alone, however, MRA may not be sufficiently accurate in certain settings to determine whether ICA disease meets surgical criteria. Although MRA has been recogn... | Internal carotid artery stenosis; Magnetic resonance angiography | 2005 |
| 9 |
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Couldwell, William T. | Far-lateral transcondylar approach: surgical technique and its application in neurenteric cysts of the cervicomedullary junction | Neurenteric cysts are rare benign lesions of the central nervous system that are lined by endodermal cell-derived epithelium. Although they occur mostly in the spine, they can occur intracranially, most often in the posterior fossa. Neurenteric cysts that are located in the anterior cervicomedullary... | | 2005 |
| 10 |
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Schmidt, Meic H. | Frameless stereotactic image-guided C1-C2 transarticular screw fixation for atlantoaxial instability: review of 20 patients | Atlantoaxial instability can result from trauma, rheumatoid arthritis, congenital malformation, or tumor invasion. The goal of treatment is stabilization of the C1-C2 complex to prevent neurologic and neurovascular compromise. First described in 1987 by Magerl and Seemann, C1-C2 transarticular screw... | Transarticular screws; Atlantoaxial instability; Frameless stereotaxy; Cervical spine; Surgical navigation; Trajectory planning | 2005 |
| 11 |
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Normann, Richard A. | Functional reorganization of primary visual cortex induced by electrical stimulation in the cat. | Compared to the high degree of plasticity observed in a juvenile, mature sensory cortices have long been held to be immutable but, recently, researchers have suggested some plasticity persists in the mature cortex. Cortical reorganization has particular saliency to the development of a cortically ba... | Cat; Electrophysiology; Phosphene; Plasticity; Receptive Field; Striate Cortex | 2005 |
| 12 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 10: fusion following decompression in patients with stenosis without spondylolisthesis | Standards. There is insufficient evidence to recommend a treatment standard. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. 1) In situ posterolateral lumbar fusion is not recommended as a treatment option in patients with lumbar stenosis in whom there is n... | Fusion; Lumbar spine; Degenerative disease; Lumbar fusion | 2005 |
| 13 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 11: interbody techniques for lumbar fusion | Standards. There is insufficient evidence to recommend a treatment standard. Guidelines. In the context of a single-level stand-alone ALIF or ALIF with posterior instrumentation, the addition of a PLF is not recommended as it increases operating room time and blood loss without influencing the like... | Fusion; Lumbar spine; Degenerative disease; Lumbar fusion; Interbody techniques | 2005 |
| 14 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 12: pedicle screw fixation as an adjunct to posterolateral fusion for low-back pain | Standard. There is insufficient evidence to recommend a treatment standard. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. 1) Pedicle screw fixation is recommended as a treatment option for patients with low-back pain treated with PLF who are at high risk... | Fusion procedures; Degenerative disease; Lumbar spine; Pedicle screw fixation; Posterolateral fusion; Low-back pain | 2005 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 13: injection therapies, low-back pain, and lumbar fusion | Standards. Facet injections are not recommended as long-term treatment for chronic low-back pain. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. The use of lumbar epidural injections or TPIs is not recommended as a treatment option for long-term relief of c... | Fusion procedures; Degenerative disease; Lumbar spine; Injection therapies; Low-back pain; Lumbar fusion | 2005 |
| 16 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 14: brace therapy as an adjunct to or substitute for lumbar fusion | Standards. There is insufficient evidence to recommend a treatment standard. Guidelines. The short-term use of a rigid lumbar support (1-3 weeks) is recommended as a treatment for low-back pain of relatively short duration (, 6 months). The use of a lumbar brace for patients with chronic low-back p... | Fusion procedures; Degenerative disease; Lumbar spine; Low-back pain; Lumbar fusion; Brace therapy | 2005 |
| 17 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 15: electrophysiological monitoring and lumbar fusion | Standards. There is insufficient evidence to recommend a treatment standard. Guidelines. Use of intraoperative SSEP or DSEP monitoring is recommended as an adjunct in those circumstances during instrumented lumbar spinal fusion procedures in which the surgeon desires immediate intraoperative inform... | Fusion procedures; Degenerative disease; Lumbar spine; Low-back pain; Lumbar fusion; Electrophysiological monitoring; EMG | 2005 |
| 18 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 16: bone graft extenders and substitutes | Standards. The use of autologous bone or rhBMP-2 bone graft substitute is recommended in the setting of an ALIF in conjunction with a threaded titanium cage. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. 1) Recombinant human BMP-2 in combination with HA ... | Lumbar fusion; Lumbar spine; Bone graft; Treatment outcome; Practice guidelines; Degenerative disease | 2005 |
| 19 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 17: bone growth stimulators and lumbar fusion | Treatment Standards. There is insufficient evidence to recommend a treatment standard. Treatment Guidelines. Either DCS or CCS is recommended as an adjunct to spinal fusion to increase fusion rates in patients who are at high risk for arthrodesis failure following lumbar PLF. Pulsed electromagnetic... | Fusion procedures; Degenerative disease; Lumbar spine; Lumbar fusion; Bone growth stimulators; Electrical stimulation devices | 2005 |
| 20 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 1: introduction and methodology | As scientific understanding of the pathophysiology of degenerative disease of the lumbar spine has increased, the possibilities for correcting the underlying problem and the resulting improvement in clinical function have expanded exponentially. Fueled by advances in material technology and surgica... | Lumbar fusion; Lumbar spine; Degenerative disease; Practice guidelines | 2005 |
| 21 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 2: assessment of functional outcome | Standards. It is recommended that functional outcome be measured in patients treated for low-back pain due to degenerative disease of the lumbar spine by using reliable, valid, and responsive scales. Examples of these scales in the low-back pain population include the following: The Spinal Stenosi... | Lumbar fusion; Lumbar spine; Degenerative disease; Practice guidelines; Treatment outcome; Functional outcome | 2005 |
| 22 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 3: assessment of economic outcome | Standards. There is insufficient evidence to recommend a standard for assessment of economic outcome following lumbar fusion for degenerative disease. Guidelines. There is insufficient evidence to recommend a guideline for assessment of economic outcome following lumbar fusion for degenerative dis... | Lumbar fusion; Lumbar spine; Degenerative disease; Practice guidelines; Treatment outcome; Economic outcome | 2005 |
| 23 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 4: radiographic assessment of fusion | Standards. Static lumbar radiographs are not recommended as a stand-alone means to assess fusion status following lumbar arthrodesis surgery. Guidelines. 1) Lateral flexion and extension radiography is recommended as an adjunct to determine the presence of lumbar fusion postoperatively. The lack ... | Lumbar fusion; Lumbar spine; Degenerative disease; Practice guidelines; Radiographic assessment | 2005 |
| 24 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 5: correlation between radiographic and functional outcome | Standards. There is insufficient evidence to recommend a treatment standard. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. It is recommended that when performing lumbar arthrodesis for degenerative lumbar disease, strategies to achieve successful radiogr... | Lumbar fusion; Lumbar spine; Degenerative disease; Practice guidelines; Functional outcome; Radiographic outcome | 2005 |
| 25 |
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Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 6: magnetic resonance imaging and discography for patient selection for lumbar fusion | Standards. There is insufficient evidence to recommend a treatment standard. Guidelines. 1) It is recommended that MR imaging be used as a diagnostic test instead of discography for the initial evaluation of patients with chronic low-back pain. 2) It is recommended that MR imaging-documented dis... | Lumbar fusion; Lumbar spine; Degenerative disease; Practice guidelines; Patient selection; Discography | 2005 |
