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Creator | Title | Description | Subject | Date |
| 126 |
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Baehr, Wolfgang | Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis | BACKGROUND: Leber congenital amaurosis (LCA), a heterogeneous early-onset retinal dystrophy, accounts for approximately 15% of inherited congenital blindness. One cause of LCA is loss of the enzyme lecithin:retinol acyl transferase (LRAT), which is required for regeneration of the visual photopigmen... | Disease Models, Animal; Genetic Vectors; Molecular Sequence Data | 2005 |
| 127 |
 |
Olivera, Baldomero M.; Yoshikami, Doju; Bulaj, Grzegorz | Post-translational amino acid isomerization: a functionally important D-amino acid in an excitatory peptide | The post-translational modification of an L- to a D-amino acid has been documented in relatively few gene products, mostly in small peptides under 10 amino acids in length. In this report, we demonstrate that a 46-amino acid polypeptide toxin has one D-phenylalanine at position 44, and that the ... | D-amino acid; Excitatory peptides; Conotoxins | 2005 |
| 128 |
 |
Kestle, John R. W. | Potentially useful outcome measures for clinical research in pediatric neurosurgery | The choice of outcome (or outcomes) and their measurement are critical for a sound clinical trial. Surgeons have traditionally measured simple outcomes such as death, duration of survival, or tumor recurrence but have recently developed more sophisticated measures of the effect of an intervention. M... | Pediatric neurosurgery | 2005 |
| 129 |
 |
Balasubramonian, Rajeev | Power-efficient approaches to reliability | Radiation-induced soft errors (transient faults) in computer systems have increased significantly over the last few years and are expected to increase even more as we move towards smaller transistor sizes and lower supply voltages. Fault detection and recovery can be achieved through redundancy. St... | Radiation-induced; Soft errors; Transient faults; Redundant thread; Trailing thread; Power consumption | 2005 |
| 130 |
 |
Fife, Paul C.; McMurtry, Patrick | Properties of the mean momentum balance in turbulent boundary layer, pipe and channel flows | The properties of the mean momentum balance in turbulent boundary layer, pipe and channel flows are explored both experimentally and theoretically. Available high-quality data reveal a dynamically relevant four-layer description that is a departure from the mean profile four-layer description tradit... | Turbulent channel flow; Pipe flow; Reynolds stress | 2005 |
| 131 |
 |
Boehme, Christoph; Friedrich, Frances | Pulsed EDMR study of charge trapping at Pb centers | Low temperature pulsed electrically detected magnetic resonance (pEDMR) measurements of charge trapping and recombination transitions involving Pb centers at the c-Si (111) /Si02 interface are presented. The results of these experiments show that when a conduction electron is trapped, it forms a str... | Charge trapping; Lande factor | 2005 |
| 132 |
 |
Couldwell, William T. | Rathke cleft cyst intracystic nodule: a characteristic magnetic resonance imaging finding | Object. The fluid content of Rathke cleft cysts (RCCs) displays variable appearances on magnetic resonance (MR) images and can appear indistinguishable from other intrasellar or suprasellar cystic lesions. Intracystic nodules associated with individual RCCs have been noted, but to date their signifi... | | 2005 |
| 133 |
 |
Adler, Frederick R. | Recent rapid increases in the right whale (Eubalaena australis) population off southern Brazil | Right whales (Eubalaena australis) that gather on a wintering ground off southern Brazil have been aerial surveyed and photographically identified since 1987. As of 2003 the Brazilian Right Whale Catalogue has 315 different individual whales of which 31 were resighted in other years (23 females, 3 y... | | 2005 |
| 134 |
 |
Zimmer, Zachary | Reciprocal effects of health and economic well-being among older adults in Taiwan and Beijing | The objectives of this study are threefold: 1) to examine whether socioeconomic status disparities in health are found in non-Western settings; 2) to assess whether socioeconomic status gradients in health endure into older ages; and 3) to evaluate the direction of causality between health and soci... | Well-being; Health | 2005 |
| 135 |
 |
Yu, Zhou | Regional disparities in homeownership trajectories: impacts of affordability, new construction, and immigration | In contrast to the 1980s, we find substantial increases in the homeownership rates of young adults in the 1990s. Focusing on the younger half of the baby boom generation, aged 35 to 44 in 2000, we explore the factors that caused steeper trajectories into homeownership in some ... | Demographics; Homeownership; Immigration | 2005 |
| 136 |
 |
Potts, Wayne K. | Relationship of virulence factor expression to evolved virulence in mouse-passaged Cryptococcus neoformans lines | Serial passage of Cryptococcus neoformans in mice increases virulence relative to the nonpassaged line. Postpassaged lines showed no difference in the expression of most known virulence factors, with the exception that the more virulent lines had smaller capsules in vitro. These data imply that othe... | Capsule; Death; Passage | 2005 |
| 137 |
 |
Caserta, Michael; Lund, Dale A.; Wright, Scott D. | Respite services: enhancing the quality of daily life for caregivers and persons with dementia | Many family caregivers are going far beyond their abilities and circumstances trying to be the best possible caregivers. This is a very commendable goal. Unfortunately, many of these caregivers are risking their own personal well-being and sometimes their family life in the process. Many caregivers... | | 2005 |
| 138 |
 |
Baehr, Wolfgang | Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT) | Lecithin:retinol acyltransferase (LRAT) is believed to be the predominant if not the sole enzyme in the body responsible for the physiologic esterification of retinol. We have studied Lrat-deficient (Lrat-/-) mice to gain a better understanding of how these mice take up and store dietary retinoids a... | Chromatography, High Pressure Liquid; Mice, Transgenic; Tissue Distribution | 2005 |
| 139 |
 |
Maloney, Thomas N. | Review: Race, liberalism, and economics | Choose any two of these three topics: race, liberalism, and economics. Now trace the connections between the two that you have chosen over the course of the nineteenth and twentieth centuries, incorporating both fundamental philosophical concepts and policy implications. Doing this could easily prod... | Racism; Classical liberalism; Paternalism | 2005 |
| 140 |
 |
Li, Minqi | Rise of China and the demise of the capitalist world-economy: exploring the historical possibilities in the 21st century | China's rising importance in the capitalist world economy raises questions of world-historic significance. How is China's internal social structure likely to evolve as China assumes different positions in the existing world system? Will China's current regime of accumulation survive the potential pr... | World economy; China; Economic development | 2005 |
| 141 |
 |
Baehr, Wolfgang | Role of photoreceptor-specific retinol dehyrogenase (prRDH) in the retinoid cycle in vivo | The retinoid cycle is a recycling system that replenishes the 11-cis-retinal chromophore of rhodopsin and cone pigments. Photoreceptor-specific retinol dehydrogenase (prRDH) catalyzes reduction of all-trans-retinal to all-trans-retinol and is thought to be a key enzyme in the retinoid cycle. We d... | Rhodopsin, Photoreceptors; prRDH (RDH8); All-trans-RDH; A2E; Retinoid cycle; Dark adaptation | 2005 |
| 142 |
 |
Freire, Juliana | Searching for hidden-web databases | Recently, there has been increased interest in the retrieval and integration of hidden-Web data with a view to leverage high-quality information available in online databases. Although previous works have addressed many aspects of the actual integration, including matching form schemata and automat... | Hidden-web databases; Web documents; Large scale information integration; Focused crawler; Form crawler | 2005 |
| 143 |
 |
Brunvand, Erik L. | Self-timed circuits using DCVSL semi-bundled delay wrappers | We present a technique for generating robust self-timed completion signals for general dynamic datapath circuits. The wrapper circuit is based on our previous domino semi-bundled delay (SBD) circuits, but uses DCVSL circuits in the wrapper for higher performance. We describe the basic SBD-DCVSL... | | 2005 |
| 144 |
 |
Miller, Jan D. | Significance of electrokinetic characterization for interpreting interfacial phenomena at planar, macroscopic interfaces | Streaming potential measurements provide valuable information for the validation and interpretation of interfacial phenomena that occur at flat macroscopic surfaces. Planar substrates have been extensively used for the interpretation of events, which occur at particulate surfaces; however, these fla... | Interfacial phenomena; Surface charge | 2005 |
| 145 |
 |
Williams, Clayton C. | Single-electron manipulation to and from a SiO2 surface by electrostatic force microscopy | Occupation of individual electron states near the surface of a SiO2 film is controlled by reversible single-electron tunneling to or from a metallic electrostatic force microscope probe. By switching the polarity of an applied dc bias between the probe and the sample to adjust the Fermi energy of ... | | 2005 |
| 146 |
 |
Bohs, Lynn A. | Solanaceae: the potato family | Shrubs, herbs, woody vines, occasionally trees, glabrous or pubescent with simple, glandular, branched, or star-shaped hairs, sometimes with prickles. Lvs alternate or paired but not truly opposite, simple or lobed to pinnately compound; stipules absent. Infl composed of variously modified terminal... | Browallia; Brugmansia; Brunfelsia; Capsicum; Cestrum; Petunia; Physalis; Solandra; Solanum; Streptosolen | 2005 |
| 147 |
 |
Smith, Philip J. | Soot in combustion simulations | Soot is the dominant source of radiative heat transfer from most practical flames. A review is presented of historical, empirical modelling approaches for estimating heat flux from fires and flames. These historical methods have drawn on empiricism to address the role of soot while seeking methods f... | Large eddy simulation; LES; Combustion simulation; Radiative heat transfer; Pool fires | 2005 |
| 148 |
 |
Eddings, Eric G.; Spinti, Jennifer C.; Smith, Philip J. | Soot volume fraction from extinction in JP-8 and heptane pool fires | Total extinction measurements from a multiple beam experiment using a 10mW laser diode are presented and compared to calculate soot volume fraction in heavily sooting pool fires from a 150 mm diameter pan of Jet Propulsion fuel 8 (JP-8) and heptane. Trends in attenuation are critiqued for the t... | Pool fires; Jet propulsion fuel | 2005 |
| 149 |
 |
Eddings, Eric G.; Smith, Philip J. | Soot volume fraction from extinction in JP-8 and heptane pool fires | Total extinction measurements from a multiple beam experiment using a 10mW laser diode are presented and compared to calculate soot volume fraction in heavily sooting pool fires from a 150 mm diameter pan of Jet Propulsion fuel 8 (JP-8) and heptane. Trends in attenuation are critiqued for the t... | Soot volume fraction; Heptane pool fires; JP-8 pool fires; Heavily sooting pool fires; Laser diagnostics | 2005 |
| 150 |
 |
Mallat, Chibli | Special Dossier on the Sabra and Shatila Case in Belgium | This dossier collects key legal documents in the Sharon affair. Being a legal dossier, the collection contains two sets of documents. The first set traces the evolution of Belgium's 1993/1999 universal jurisdiction law by making available in English, in several cases for the first time, translati... | | 2005 |
