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CreatorTitleDescriptionSubjectDate
401 Jorgensen, ErikMutations in β-spectrin disrupt axon outgrowth and sarcomere structureB-Spectrin is a major component of the membrane skeleton, a structure found at the plasma membrane of most animal cells. B-Spectrin and the membrane skeleton have been proposed to stabilize cell membranes, generate cell polarity, or localize specific membrane proteins. We demonstrate that the Caen...2000
402 Capecchi, Mario R.N-formylmethionyl-sRNA as the initiator of protein synthesis.A bizarre fast about Nterminal groups of bacterial proteins. Instead of a random mixture, that the great majority of N-terminal groups were either methionine or alanine. This finding suggested that methionine and alanine constituted start signals for the initiation of polypeptide chains. Alternative...Electrophoresis; Formates; In Vitro; Methionine1966-01-01
403 Jorgensen, ErikNano-fEM: Protein localization using photo-activated localization microscopy and electron microscopyMapping the distribution of proteins is essential for understanding the function of proteins in a cell. Fluorescence microscopy is extensively used for protein localization, but subcellular context is often absent in fluorescence images. Immuno-electron microscopy, on the other hand, can localize pr...2012-01-01
404 National Medals of Science and Technology Awards (2001) Ceremony and Banquet, held June 13, 2002This 51 minutes, 5 seconds video is divided into two parts: the first part is a film introducing the award winners and their achievements; the second is the presentation of the actual awards by George W. Bush, President of the United States. Medal winners were: Mario R. Capecchi for his pioneering...Molecular genetics; Gene targeting; Transgenic mice; Gene expression; Genetic engineering; Capecchi, Mario R.; Science - Awards - United States; Awards presentations2002
405 Seger, JonNatural history and evolution of paper-waspsPaper-wasps occupy a special place in the history of animal behavior. Temperate species o f Polistes are large, beautiful, intelligent, adaptable, easy to observe, and thoroughly committed to social life. They are also aptly named, being intensely political, in the limited sense that any nonhuman an...Individuals; Excellent; Phylogeny1997
406 Sekercioglu, CaganThe need to quantify ecosystem services provided by birdsWhat are birds worth-what is their actual dollar value to human society? To most of us in the ornithological community, birds are invaluable. But in these times we need more specific rationales to convince policy makers and business leaders to include bird conservation in land-use and development de...2011-01-01
407 Clayton, Dale H.Neotropical tineidae, II: biological notes and descriptions of two new moths phoretic on spiny pocket mice in Costa Rica (Lepidoptera: Tineoidea)Two new species of tineid moths discovered riding on the backs of two species of spiny pocket mice (Heteromyidae) in Costa Rica are described. Amydria selvae, new species, was found on Heteromys desmarestianus Gray in the rainforest at Finca La Selva and Ptilopsaltis santarosae, new species, occurr...Neotropical Tineidae; Phoretic moths; Amydria selvae; Heteromys desmarestianus; Ptilopsaltis santarosae; Liomys salvini; Mouse moths1986
408 Jorgensen, ErikNeural plasticityNeural plasticity refers to functional changes in the nervous system and therefore encompasses a range of phenomena from changes at synapses observed on a microscopic scale to changes in behavior observed in the whole animal. These diverse phenomena are related since changes in synapses are believ...Synapses; Nervous System; Development1997
409 Yamaguchi, AyakoNeurocircuitry underlying vocal production of the African clawed frog, Xenopus laevisThis poster describes how motor and premotor neurons are interconnected to each other using electrophysiological and pharmacological techniques.Vocalizations; Central pattern generator; Motor programs; Premotor neurons; Whole-cell patch-clamp recordings2014
410 Olivera, Baldomero M.; Gray, William Robert; McIntosh, J. MichaelNeuronal calcium channel inhibitors: synthesis of ω-conotoxin GVIA and effects on 45Ca-uptake by synaptosomesWe previously described a 27-amino acid peptide neurotoxin from the venom of Conus geographus, wconotoxin GVIA, which inhibits neuronal voltage-activated calcium channels. In this paper we describe the total synthesis of ω-conotoxin GVIA and demonstrate that it efficiently blocks voltage-activat...Neuronal calcium; Calcium channels; Channel inhibitors; [omega]-conotoxin GVIA1987
411 Coley, Phyllis D.New cytotoxic cinnamic acid derivatives from leaves of Bonamia trichanthaBioassay-guided fractionation of the methanolic extract of the young leaves of Bonamia trichantha led to the isolation of four new cinnamic acid derivatives trichanthins A-D (l-4).Their structures were established by spectroscopic methods. All compounds were tested in cytotoxic assays against the MC...Bonamia trichantha; Cinnamic acid; Caffeic acid ester; p-Coumaric acid ester: Farnesol; Z-(l l)-hexadecen-l-ol; Cytotoxicity2006
412 Olivera, Baldomero M.; McIntosh, J. Michael; Gray, William Robert; Hillyard, David R.New family of conotoxins that block voltage-gated sodium channelsConus peptides, including ω-conotoxins and α-conotoxins (targeting calcium channels and nicotinic acetylcholine receptors, respectively) have been useful ligands in neuroscience. In this report, we describe a new family of sodium channel ligands, the μO-conotoxins.Conotoxins; Sodium channel blockers1995
413 Olivera, Baldomero M.; Gray, William RobertNew family of Conus peptides targeted to the nicotinic acetylcholine receptorIn this work, a new family of Conus peptides, the αA-conotoxins, which target the nicotinic acetylcholine receptor, is defined. The first members of this family have been characterized from the eastern Pacific species, Conus purpurascens (the purple cone); three peptides that cause paralysis in fis...Conotoxins; Conus peptides; Conus purpurascens; Purple cone snail1995
414 Clayton, Dale H.New genus and three new species of chewing lice (Phthiraptera: Philopteridae) from Peruvian ovenbirds (Passeriformes: Furnariidae)The new genus Furnariphilus is described to include three new species from Peruvian hosts within the passerine family Furnariidae, subfamily Furnariinae: F. pagei, the type species of the genus, from Furnarius leucopus Swainson; F. griffithsi from Sclerurus mexicanus Sclater; and F. parkeri from Scl...Chewing lice; Peruvian ovenbirds; Phthiraptera; Furnariphilus; Ectoparasites; Peru; Furnarius leucopus; Sclerurus mexicanus; Sclerurus caudacutus1995
415 Cieri, RobertNew insight into the evolution of the vertebrate respiratory system and the discovery of unidirectional airflow in iguana lungsThe generally accepted framework for the evolution of a key feature of the avian respiratory system, unidirectional airflow, is that it is an adaptation for efficiency of gas exchange and expanded aerobic capacities, and therefore it has historically been viewed as important to the ability of birds ...2014-11-17
416 Farmer, Colleen G.New perspective on the origin of endothermyA new hypothesis for the origin of endothermy in birds is discussed. I suggest extensive parental care provided the initial impetus for the evolution of endothermy. Among extant animals one of the most important functions of an endothermic metabolism is the incubation of embryos. Furthermore, I prop...Endothermy; Parental care; Thermogenesis; Reproduction; Hormone; Aerobic capacity2001
417 Bohs, Lynn A.New species of Solanum and Capsicum (Solanaceae) from Bolivia, with clarification of nomenclature in some Bolivian SolanumBolivian floristic diversity is high, reflecting its great topographic and habitat diversity. Habitats in Bolivia range from seasonally flooded savannas to arid Chaco and high elevation deserts to hyper-humid montane and lowland rainforests.Capsicum; Solanum; Bolivia; Biodiversity2006
418 Bohs, Lynn A.New species of Solanum section Cyphomandropsis (Solanaceae) from BoliviaA new species of Solanum sect. Cyphomandropsis (Solanaceae), S. hibernum, is described from the western part of Dept. Santa Cruz, Bolivia. Its strongly discolorous leaves densely covered below with white dendritic hairs distinguish it from the other species in the section.Solanum hibernum; Cyphomandropsis1994
419 Olivera, Baldomero M.; Gray, William Robert; McIntosh, J. MichaelNew α-conotoxin which targets α3ß2 nicotinic acetylcholine receptorsWe have isolated a 16-amino acid peptide from the venom of the marine snail Conus magus which potently blocks nicotinic acetylcholine receptors (nAChRs) composed of α3ß2 subunits. This peptide, named a-conotoxin MII, was identified by electrophysiologically screening venom fractions against cl...Conotoxins; a-conotoxin MII; Conus magus1996
420 Olivera, Baldomero M.Nicotinic acetylcholine receptor ligand of unique specificity, α-conotoxin ImIWe report the isolation, characterization, and total synthesis of a small peptide ligand for nicotinic acetylcholine receptors (nAChRs). It is highly active against the neuromuscular receptor in frog but noitn mice. In contrast, it induces seizures when injected centrally in mice and rats, suggesti...Conotoxins; a-conotoxin ImI1994
421 Olivera, Baldomero M.; Ireland, Chris M.NMR structures of conotoxinsThis review discusses the methodology, structural details, and biological implications regarding NMR structures of conotoxins. NMR and molecular modeling techniques have improved to the point that three-dimensional structures of conotoxins can now be determined with a significant degree of confiden...Conotoxins1996
422 Clayton, Dale H.Nocturnal foraging of yellow-crowned night herons in the BahamasDetailed observations of nocturnal foraging of the Yellow-crowned Night Heron (Nycticorax violacevs) are not to be found in the literature, though this species commonly feeds at night (Kushlan 1978, Riegner 1982a). I observed several Yellow-crowned Night Herons foraging during November and December...Nocturnal foraging; Bahamas; Nycticorax violacevs1985
423 Goller, FranzNonlinear model predicts diverse respiratory patterns of birdsongA central aspect of the motor control of birdsong production is the capacity to generate diverse respiratory rhythms, which determine the coarse temporal pattern of song. The neural mechanisms that underlie this diversity of respiratory gestures and the resulting acoustic syllables are largely unkn...Sound; Syllables; Song2006
424 Davidson, Diane W.Nonnative brome grasses in the new national monumentIncluded within the boundaries of the Grand-Staircase Escalante National Monument are a number of noxious weeds for which the BLM mandates control. In addition to listed weeds are nonnative brome grasses [Bromus tectorum and Bromus rubens), which can potentially convert native ecosystems to biologic...Noxious weeds, Cheatgrass,1998
425 Thomas, Kirk R.; Capecchi, Mario R.Nonreciprocal exchanges of information between DNA duplexes coinjected into mammalian. cell nucleiWe have examined the mechanism of homologous recombination between plasmid molecules coinjected into cultured mammalian cells. Cell lines containing recombinant DNA molecules were obtained by selecting for the reconstruction of a functional Neor gene from two plasmids that bear different amber mutat...Animals; Cells, Cultured; DNA Restriction Enzymes; Kinetics1985-01
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