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| Creator | Title | Description | Subject | Date | ||
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Potts, Wayne K. | Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: can we trust congenic animals? | Congenic strains of mice are assumed to differ only at a single gene or region of the genome. These mice have great importance in evaluating the function of genes. However, their utility depends on the maintenance of this true congenic nature. Although, accumulating evidence suggests that congenic ... | Strains; Mutations; Pathogen | 2004 |
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Potts, Wayne K. | Major histocompatibility complex heterozygote superiority during coinfection | Genes of the major histocompatibility complex (MHC) play a critical role in immune recognition, and many alleles confer susceptibility to infectious and autoimmune diseases. How these deleterious alleles persist in populations is controversial. | Pathogen; MHC; Homozygotes | 2003 |
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