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Creator | Title | Description | Subject | Date |
| 76 |
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Gerig, Guido | Noise-induced bias in low-direction diffusion tensor MRI: replication of Monte-Carlo simulation with in-vivo scans | Clinical neuroimaging studies involving diffusion tensor MRI (DTI) require precise estimation of diffusion properties for statistical analysis. Tensor derived measures such as fractional anisotropy (FA) and trace are often analyzed for hypothesis testing. Given the limited scanning time typically av... | | 2007-01-01 |
| 77 |
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Gerig, Guido | Normative modeling of early brain maturation from longitudinal DTI reveals twin-singleton differences | Early brain development of white matter is characterized by rapid organization and structuring. Magnetic Resonance diffusion tensor imaging (MR-DTI) provides the possibility of capturing these changes non-invasively by following individuals longitudinally in order to better understand departures fro... | | 2014-01-01 |
| 78 |
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Wunderlich, Adam James | On efficient assessment of image-quality metrics based on linear model observers | This paper is motivated by the problem of image-quality assessment using model observers for the purpose of development and optimization of medical imaging systems. Specifically, we present a study regarding the estimation of the receiver operating characteristic (ROC) curve for the observer and ass... | | 2012-01-01 |
| 79 |
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Gerig, Guido | Parametric regression scheme for distributions: analysis of DTI fiber tract diffusion changes in early Brain Development | Temporal modeling frameworks often operate on scalar variables by summarizing data at initial stages as statistical summaries of the underlying distributions. For instance, DTI analysis often employs summary statistics, like mean, for regions of interest and properties along fiber tracts for populat... | | 2014-01-01 |
| 80 |
 |
Gerig, Guido | Patient-tailored connectomics visualization for the assessment of white matter atrophy in traumatic brain injury | Available approaches to the investigation of traumatic brain injury (TBI) are frequently hampered, to some extent, by the unsatisfactory abilities of existing methodologies to efficiently define and represent affected structural connectivity and functional mechanisms underlying TI-related pathology.... | | 2012-01-01 |
| 81 |
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Kuhlman, Brian | PHD Entrepreneur | The idea for this speech began when my friends and family started asking what I would do after graduating with my PhD in psychology. Folks tended to get a bit confused when I replied that my plan is to start a business. You don't need a PhD to do that! It's true. The path leading from PhD to Entrepr... | entrepreneur; PhD; doctoral; industry; academia | 2013-05-03 |
| 82 |
 |
Gerig, Guido | Population-based fitting of medial shape models with correspondence optimization | A crucial problem in statistical shape analysis is establishing the correspondence of shape features across a population. While many solutions are easy to express using boundary representations, this has been a considerable challenge for medial representations. This paper uses a new 3-D medial model... | | 2007-01-01 |
| 83 |
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Gerig, Guido | Prenatal mild ventriculomegaly predicts abnormal development of the neonatal brain | Background: Many psychiatric and neurodevelopmental disorders are associated with mild enlargement of the lateral ventricles thought to have origins in prenatal brain development. Little is known about development of the lateral ventricles and the relationship of prenatal lateral ventricle enlargeme... | | 2008-01-01 |
| 84 |
 |
Gerig, Guido | Quality control of diffusion weighted images | Diffusion Tensor Imaging (DTI) has become an important MRI procedure to investigate the integrity of white matter in brain in vivo. DTI is estimated from a series of acquired Diffusion Weighted Imaging (DWI) volumes. DWI data suffers from inherent low SNR, overall long scanning time of multiple dire... | | 2010-01-01 |
| 85 |
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Gerig, Guido | Quantifying regional growth patterns through longitudinal analysis of distances between multimodal MR intensity distributions | Quantitative analysis of early brain development through imaging is critical for identifying pathological development, which may in turn affect treatment procedures. We propose a framework for analyzing spatiotemporal patterns of brain maturation by quantifying intensity changes in longitudinal MR i... | | 2012-01-01 |
| 86 |
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Gerig, Guido | Reduced relationship to cortical white matter volume revealed by Tractography-based segmentation of the corpus callosum in young children with developmental delay | Objective: The corpus callosum is the primary anatomical substrate for inter-hemispheric communication, which is important for a range of adaptive and cognitive behaviors in early development. Previous studies that have measured the corpus callosum in developmental populations have been limited by t... | | 2006-01-01 |
| 87 |
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Gerig, Guido | Regional gray matter growth, sexual dimorphism, and cerebral asymmetry in the Neonatal Brain | Although there has been recent interest in the study of childhood and adolescent brain development, very little is known about normal brain development in the first few months of life. In older children, there are regional differences in cortical gray matter development, whereas cortical gray and wh... | | 2007-01-01 |
| 88 |
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Gerig, Guido | Segmentation of serial MRI of TBI patients using personalized atlas construction and topological change estimation | Traumatic brain injury (TBI) due to falls, car accidents, and warfare affects millions of people annually. Determining personalized therapy and assessment of treatment efficacy can substantially benefit from longitudinal (4D) magnetic resonance imaging (MRI). In this paper, we propose a method for s... | | 2012-01-01 |
| 89 |
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Gerig, Guido | Semi-automated application for kidney motion correction and filtration analysis in MR renography | Altered renal function commonly affects patients with cirrhosis, a consequence of chronic liver disease. From lowdose contrast material-enhanced magnetic resonance (MR) renography, we can estimate the Glomerular Filtration Rate (GFR), an important parameter to assess renal function. Two-dimensional ... | | 2014-01-01 |
| 90 |
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Macleod, Robert S. | Sensitivity of epicardial electrical markers to acute ischemia detection | Introduction: We hypothesize that electrocardiographic measurements from the intramyocardial space contain more sensitive markers of ischemia than those detectable on the epicardium. The goal of this study was to evaluate different electrical markers for their potential to detect the earliest phases... | | 2014-01-01 |
| 91 |
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Gerig, Guido | Spatial intensity prior correction for tissue segmentation in the developing human brain | The degree of white matter (WM) myelination is rather inhomogeneous across the brain. As a consequence, white matter appears differently across the cortical lobes in MR images acquired during early postnatal development. At 1 year old specifically, the gray/white matter contrast of MR images in pref... | | 2011-01-01 |
| 92 |
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Gerig, Guido | Spatio-temporal analysis of early brain development | Analysis of human brain development is a crucial step for improved understanding of neurodevelopmental disorders. We focus on normal brain development as is observed in the multimodal longitudinal MRI/DTI data of neonates to two years of age. We present a spatio-temporal analysis framework using Gom... | | 2010-01-01 |
| 93 |
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Gerig, Guido | Spatiotemporal modeling of distribution-valued data applied to DTI tract evolution in infant neurodevelopment | This paper proposes a novel method that extends spatiotemporal growth modeling to distribution-valued data. The method relaxes assumptions on the underlying noise models by considering the data to be represented by the complete probability distributions rather than a representative, single-valued su... | | 2013-01-01 |
| 94 |
 |
Gerig, Guido | Statistical group differences in anatomical shape analysis using Hotelling T2 Metric | Shape analysis has become of increasing interest to the neuroimaging community due to its potential to precisely locate morphological changes between healthy and pathological structures. This manuscript presents a comprehensive set of tools for the computation of 3D structural statistical shape anal... | | 2007-01-01 |
| 95 |
 |
Gerig, Guido | Statistical growth modeling of longitudinal DT-MRI for regional characterization of early brain development | A population growth model that represents the growth trajectories of individual subjects is critical to study and understand neurodevelopment. This paper presents a framework for jointly estimating and modeling individual and population growth trajectories, and determining significant regional diffe... | | 2012-01-01 |
| 96 |
 |
Gerig, Guido | Statistical shape analysis of brain structures using spherical wavelets | We present a novel method of statistical surface-based morphometry based on the use of non-parametric permutation tests and a spherical wavelet (SWC) shape representation. As an application, we analyze two brain structures, the caudate nucleus and the hippocampus, and compare the results obtained to... | | 2007-01-01 |
| 97 |
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Gerig, Guido | Statistical shape analysis of Multi-Object complexes | An important goal of statistical shape analysis is the discrimination between populations of objects, exploring group differences in morphology not explained by standard volumetric analysis. Certain applications additionally require analysis of objects in their embedding context by joint statistical... | | 2007-01-01 |
| 98 |
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Gerig, Guido | Statistics of populations of images and its embedded objects: driving applications in neuroimaging | Work in progress towards modeling shape statistics of multi-object complexes is presented. Constraints defined by the set of objects such as a compact representation of object shape relationships and correlation of shape changes might have advantages for automatic segmentation and group discriminati... | | 2006-01-01 |
| 99 |
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Gerig, Guido | Structural integrity of the uncinate fasciculus in geriatric depression: relationship with age of onset | Background: The uncinate fasciculus connects limbic structures, such as the hippocampus and amygdala, with frontal regions. This study utilized diffusion tensor imaging to examine the structural integrity of the uncinate fasciculus in late-life depression. Method: 18 elderly depressed and 19 elderly... | | 2007-01-01 |
| 100 |
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Gerig, Guido | Subcortical structure segmentation using probabilistic atlas priors | The segmentation of the subcortical structures of the brain is required for many forms of quantitative neuroanatomic analysis. The volumetric and shape parameters of structures such as caudate are employed to characterize a disease or its evolution. This paper presents our fully automatic segmentati... | | 2007-01-01 |
