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| Creator | Title | Description | Subject | Date | ||
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Coley, Phyllis D.; Kursar, Thomas A. | Novel DNA-based microfluorimetric method to evaluate antimalarial drug activity | This paper describes the development of a novel microfluorimetric assay to measure the inhibition of Plasmodium falciparum based on the detection of parasitic DNA by intercalation with PicoGreen®. The method was used to determine parasite inhibition profiles and 50% inhibitory concentration values ... | Microfluorimetric assay; Plasmodium falciparum; Chloroquine; Drug discovery | 2004 |
| 2 |
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Coley, Phyllis D. | On turning green into gold | Anthropogenic effects on the climate and biodiversity of our planet are among the most troubling and perhaps irreversible threats facing scientists, policymakers, and citizens. Yet many scientists are reluctant or unsure of how to apply their expertise in basic science to these pressing real-world p... | Bioprospecting; Drug discovery; Active compounds; Panama | 2008 |
| 3 |
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Coley, Phyllis D.; Kursar, Thomas A. | Using ecological criteria to design plant collection strategies for drug discovery | Tropical forests are one of the most diverse and endangered habitats on earth. They have also been portrayed as a source of future pharmaceuticals, yet finding useful compounds can be both scientifically and politically challenging. Increasingly, over the past decade, the potential value of medicina... | Drug discovery; Biodiversity | 2003 |
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